David Holtzman
Washington University in St. Louis
H-index: 205
North America-United States
Top articles of David Holtzman
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins | Neuron | Michael R Strickland Michael J Rau Brock Summers Katherine Basore John Wulf | 2024/1/13 |
Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner | Molecular Neurodegeneration | Megan E Bosch Hemraj B Dodiya Julia Michalkiewicz Choonghee Lee Shabana M Shaik | 2024/2/17 |
Use of a Blood Biomarker Test Improves Economic Utility in the Evaluation of Older Patients Presenting with Cognitive Impairment | Population Health Management | William J Canestaro Randall J Bateman David M Holtzman Mark Monane Joel B Braunstein | 2024/3/28 |
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model | bioRxiv | Gillian K Carling Li Fan Nessa R Foxe Kendra Norman Pearly Ye | 2024 |
Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study | The Lancet Neurology | Julie K Wisch Nicole S McKay Anna H Boerwinkle James Kennedy Shaney Flores | 2024/5/1 |
Baseline levels and longitudinal rates of change in plasma Aβ42/40 among self-identified Black/African American and White individuals | Chengjie Xiong Suzanne Schindler Jingqin Luo John Morris Randall Bateman | 2024/1/8 | |
Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease. | Carlos Cruchaga Muhammad Ali Yuanyuan Shen Anh Do Lihua Wang | 2024/2/16 | |
Disease staging of Alzheimer’s disease using a CSF-based biomarker model | Nature Aging | Gemma Salvadó Kanta Horie Nicolas R Barthélemy Jacob W Vogel Alexa Pichet Binette | 2024/3/21 |
Mapping sleep's oscillatory events as a biomarker of Alzheimer's disease | Alzheimer's & Dementia | Rachelle L Pulver Eugene Kronberg Lindsey M Medenblik Vitaly O Kheyfets Alberto R Ramos | 2024/1 |
Midpoint of Sleep is Associated with Sleep Quality in Older Adults with and without Symptomatic Alzheimer’s Disease | Sleep Advances | Scott C Sauers Cristina D Toedebusch Rachel Richardson Adam P Spira John C Morris | 2024/4/15 |
Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's … | Jeffery M Vance Lindsay A Farrer Yadong Huang Carlos Cruchaga Bradley T Hyman | 2024/1/5 | |
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist | Neuron | Alexandra Litvinchuk Jung H Suh Jing L Guo Karin Lin Sonnet S Davis | 2024/2/7 |
Clinical validation of the PrecivityAD2 blood test: A mass spectrometry‐based test with algorithm combining% p‐tau217 and Aβ42/40 ratio to identify presence of brain amyloid | Alzheimer's & Dementia | Matthew R Meyer Kristopher M Kirmess Stephanie Eastwood Traci L Wente‐Roth Faith Irvin | 2024/3/16 |
CSF biomarkers of immune activation and Alzheimer’s disease for predicting cognitive impairment risk in the elderly | Science Advances | Francis Shue Launia J White Rachel Hendrix Jason Ulrich Rachel L Henson | 2024/4/3 |
Current understanding of the Alzheimer’s disease-associated microbiome and therapeutic strategies | Dong-oh Seo David M Holtzman | 2024/1/4 | |
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread | Cell | Yun Chen Sihui Song Samira Parhizkar Jennifer Lord Yiyang Zhu | 2024/1/18 |
Anti-ApoE antibodies | 2024/3/12 | ||
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model | Science Translational Medicine | Jinchao Hou Yun Chen Zhangying Cai Gyu Seong Heo Carla M Yuede | 2024/4/3 |
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial | JAMA neurology | Olivia Wagemann Haiyan Liu Guoqiao Wang Xinyu Shi Tobias Bittner | 2024 |
Aducanumab anti-amyloid immunotherapy induces sustained microglial and immune alterations | Journal of Experimental Medicine | Mika P Cadiz Katelin A Gibson Kennedi T Todd David G Nascari Nashali Massa | 2024/1/16 |
