David DeNardo

David DeNardo

Washington University in St. Louis

H-index: 51

North America-United States

About David DeNardo

David DeNardo, With an exceptional h-index of 51 and a recent h-index of 45 (since 2020), a distinguished researcher at Washington University in St. Louis, specializes in the field of Tumor Microenviorment, Immunology, Pancreatic Cancer.

His recent articles reflect a diverse array of research interests and contributions to the field:

“RIPping” off Pancreas Cancer's Blockage of Immune Surveillance

Senescent CAFs Mediate Immunosuppression and Drive Breast Cancer Progression

Pancreatic Cancer's PD1-Roadblock: When T-Cell Reinvigoration Is Not Enough

Targeting IL-1β mitigates radiation induced MDSC expansion & improves survival in glioblastoma

Abstract C003: RAMP 205: A phase 1b/2a study of gemcitabine, nab-paclitaxel, avutometinib, and defactinib in untreated metastatic pancreatic ductal adenocarcinoma

Tumor-associated fibrosis leads to an increase in T-cell exhaustion and impairs tumor control in non-small cell lung cancer

Abstract A091: The RAF/MEK clamp avutometinib as the backbone of therapy for pancreatic cancer: Novel combinations with standard of care chemotherapy, FAK inhibitors, KRAS G12D …

Combined inhibition of RAF, MEK and FAK increases PDAC responsiveness to cytotoxic-and immune therapy

David DeNardo Information

University

Position

School of Medicine

Citations(all)

21739

Citations(since 2020)

14011

Cited By

12318

hIndex(all)

51

hIndex(since 2020)

45

i10Index(all)

83

i10Index(since 2020)

70

Email

University Profile Page

Washington University in St. Louis

Google Scholar

View Google Scholar Profile

David DeNardo Skills & Research Interests

Tumor Microenviorment

Immunology

Pancreatic Cancer

Top articles of David DeNardo

Title

Journal

Author(s)

Publication Date

“RIPping” off Pancreas Cancer's Blockage of Immune Surveillance

Cancer Discovery

Xiuting Liu

Blake E Sells

David G DeNardo

2024/2/8

Senescent CAFs Mediate Immunosuppression and Drive Breast Cancer Progression

Cancer discovery

Jiayu Ye

John M Baer

Douglas V Faget

Vasilios A Morikis

Qihao Ren

...

2024/4/17

Pancreatic Cancer's PD1-Roadblock: When T-Cell Reinvigoration Is Not Enough

Clinical Cancer Research

Varintra E Lander

David G DeNardo

2024/2/1

Targeting IL-1β mitigates radiation induced MDSC expansion & improves survival in glioblastoma

Cancer Research

Subhajit Ghosh

Jiayi Huang

David DeNardo

Dennis Hallahan

Jerry Jaboin

...

2024/3/22

Abstract C003: RAMP 205: A phase 1b/2a study of gemcitabine, nab-paclitaxel, avutometinib, and defactinib in untreated metastatic pancreatic ductal adenocarcinoma

Cancer Research

Kian-Haut Lim

Manuel Hidalgo

Mark H O'Hara

Kristen R Spencer

Ignacio Garrido-Laguna

...

2024/1/16

Tumor-associated fibrosis leads to an increase in T-cell exhaustion and impairs tumor control in non-small cell lung cancer

Cancer Research

Usman Y Panni

Varun Shenoy

Brett Knolhoff

Faiz Ahmed

Brett Herzog

...

2024/3/22

Abstract A091: The RAF/MEK clamp avutometinib as the backbone of therapy for pancreatic cancer: Novel combinations with standard of care chemotherapy, FAK inhibitors, KRAS G12D …

Cancer Research

Silvia Coma

Xiuting Liu

Noah L Pieper

Wen-Hsuan Chang

Kirsten L Bryant

...

2024/1/16

Combined inhibition of RAF, MEK and FAK increases PDAC responsiveness to cytotoxic-and immune therapy

Cancer Research

Xiuting Liu

John Baer

Brett Knolhoff

Graham Hogg

Faiz Ahmad

...

2024/3/22

Intratumoral T-cell receptor repertoire composition predicts overall survival in patients with pancreatic ductal adenocarcinoma

OncoImmunology

Vikram S Pothuri

Graham D Hogg

Leah Conant

Nicholas Borcherding

C Alston James

...

2024/12/31

sc2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data

PLoS computational biology

Jiarui Feng

S Peter Goedegebuure

Amanda Zeng

Ye Bi

Ting Wang

...

2024/1/5

Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer

Nature Communications

Ashenafi Bulle

Peng Liu

Kuljeet Seehra

Sapana Bansod

Yali Chen

...

2024/3/20

Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer

Cancer discovery

Jad I Belle

Devashish Sen

John M Baer

Xiuting Liu

Varintra E Lander

...

2024/4/29

Chemokine Receptor 2 Targeted PET/CT Imaging Distant Metastases in Pancreatic Ductal Adenocarcinoma

ACS Pharmacology & Translational Science

Xiaohui Zhang

Lisa Detering

Gyu Seong Heo

Deborah Sultan

Hannah Luehmann

...

2023/12/5

Abstract P3-06-07: Phase Ib/II study to evaluate safety and tolerability of cabiralizumab in combination with nivolumab and neoadjuvant chemotherapy in patients with localized …

Cancer Research

Andrew A Davis

Leonel Hernandez-Aya

Jingqin Luo

Mateusz Opyrchal

Foluso O Ademuyiwa

...

2023/3/1

Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer

Science translational medicine

Brett H Herzog

John M Baer

Nicholas Borcherding

Natalie L Kingston

Jad I Belle

...

2023/6/7

Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology

Cancer Immunology, Immunotherapy

Usman Y Panni

Michael Y Chen

Felicia Zhang

Darren R Cullinan

Lijin Li

...

2023/8

Correction: Defactinib, Pembrolizumab, and Gemcitabine in Patients with Advanced Treatment Refractory Pancreatic Cancer: a Phase I Dose Escalation and Expansion Study

Clinical Cancer Research

Andrea Wang-Gillam

Kian-Huat Lim

Robert McWilliams

Rama Suresh

Albert C Lockhart

...

2023/11/14

Radiation-induced circulating myeloid-derived suppressor cells induce systemic lymphopenia after chemoradiotherapy in patients with glioblastoma

Science translational medicine

Subhajit Ghosh

Jiayi Huang

Matthew Inkman

Jin Zhang

Sukrutha Thotala

...

2023/1/25

p38MAPKα stromal reprogramming sensitizes metastatic breast cancer to immunotherapy

Cancer discovery

Douglas V Faget

Xianmin Luo

Matthew J Inkman

Qihao Ren

Xinming Su

...

2023/6/2

Costimulatory domains direct distinct fates of CAR-driven T-cell dysfunction

Blood, The Journal of the American Society of Hematology

Mehmet Emrah Selli

Jack H Landmann

Marina Terekhova

John Lattin

Amanda Heard

...

2023/6/29

See List of Professors in David DeNardo University(Washington University in St. Louis)