David C. Linehan
University of Rochester
H-index: 67
North America-United States
Top articles of David C. Linehan
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
A phase 1b/2 trial of pepinemab and avelumab as second line therapy for patients with metastatic pancreatic adenocarcinoma. | Bailey Hilty Luis I Ruffolo Brian A Belt Matthew Byrne Yatee A Dave | 2024/1/20 | |
Abstract A035: Stromal composition, fibroblast heterogeneity and spatial organization in pancreatic adenocarcinoma | Cancer Research | Dalia Elganainy Andressa Dias Costa Alexander Jordan Suryun Kim Sara A Väyrynen | 2024/1/16 |
Smad4 restricts injury-provoked biliary proliferation and carcinogenesis | Disease Models & Mechanisms | William B Alexander Wenjia Wang Margaret A Hill Michael R O'Dell Luis I Ruffolo | 2024/6/1 |
Determination of permissive and restraining cancer-associated fibroblast (DeCAF) subtypes | Cancer Research | Xianlu Laura Peng Elena Kharitonova Joseph Kearney Yi Xu Priscilla Chan | 2024/3/22 |
Cd73 and PD-L1 dual blockade Amplifies antitumor efficacy of SBRT in murine PDAC models | Journal for Immunotherapy of Cancer | Jian Ye Nicholas W Gavras David C Keeley Angela L Hughson Gary Hannon | 2023 |
Phase 1b/2 trial of pepinemab plus avelumab as second line combination immunotherapy for patients with metastatic pancreatic adenocarcinoma. | Luis I Ruffolo Terrence Lee Fisher Elizabeth E Evans Crystal L Mallow Megan Boise | 2023/6/1 | |
Predictors of opioid-free discharge after laparoscopic cholecystectomy | The American Journal of Surgery | Alexa D Melucci Yatee A Dave Olivia F Lynch Shawn Hsu Mariah R Erlick | 2023/1/1 |
Radiation therapy exacerbates tumor-promoting innervation and nerve signaling in rectal cancer | International Journal of Radiation Oncology* Biology* Physics | Taylor P Uccello Maggie L Lesch Nicholas A Ullman Sarah A Kintzel Lauren B Gradzewicz | 2023/3/1 |
Spatially resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intratumoral heterogeneity | Cancer research | Hannah L Williams Andressa Dias Costa Jinming Zhang Srivatsan Raghavan Peter S Winter | 2023/2/3 |
Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer | bioRxiv | Angela L Hughson Gary Hannon Noah A Salama Tara G Vrooman Caroline A Stockwell | 2023/11/2 |
The divergent role of the GM-CSF/GM-CSFR signaling pathway in cholangiocarcinoma and pancreatic ductal adenocarcinoma. | Yatee A Dave Paul R Burchard Luis I Ruffolo Nicholas A Ullman Mary Georger | 2023/2/1 | |
New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy | Cell Death & Disease | Taylor P Uccello Maggie L Lesch Sarah A Kintzel Lauren B Gradzewicz Lillia Lamrous | 2023/7/26 |
Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1 | Cancers | Negar Khazan Emily R Quarato Niloy A Singh Cameron WA Snyder Taylor Moore | 2023/6/30 |
A phase 1B/2 trial of avelumab and pepinemab as second line for metastatic pancreatic adenocarcinoma | HPB | LI Ruffolo KM Jackson NA Ullman PR Burchard M Georger | 2023/1/1 |
Early Postoperative ERAS Compliance is Associated with Decreased Length of Stay and Complications Following Liver Resection | HPB | P Burchard Y Dave A Loria N Parikh K Pineda-Solis | 2022/1/1 |
Abstract PO025: GM-CSF neutralization enhances the efficacy of chemotherapy in an orthotopic murine model of cholangiocarcinoma | Clinical Cancer Research | Yatee A Dave Paul R Burchard Nicholas A Ullman Mary Georger Luis I Ruffolo | 2022/9/1 |
GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity | Gut | Luis I Ruffolo Katherine M Jackson Peyton C Kuhlers Benjamin S Dale Nathania M Figueroa Guilliani | 2022/7/1 |
Cyclooxygenase-2 Inhibition with Celecoxib Delays Tumor Growth in an Orthotopic Murine Model of Cholangiocarcinoma–A Novel Therapeutic Strategy for Cholangiocarcinoma | HPB | Y Dave P Burchard A Chacon L Ruffolo N Ullman | 2022/1/1 |
Intrathecal morphine and effect on opioid consumption and functional recovery after pancreaticoduodenectomy | Journal of the American College of Surgeons | Paul R Burchard Alexa D Melucci Olivia Lynch Anthony Loria Yatee A Dave | 2022/9/1 |
" Reverse abscopal effect": Immunologically cold tumors alter systemic immunity and confer PD-1 resistance to immunologically hot tumors in synchronous melanoma | Cancer Research | Shuyang S Qin Booyeon J Han Alexander C Chacon Alexa D Melucci Alyssa R Williams | 2022/6/15 |
