David Bartel

David Bartel

Massachusetts Institute of Technology

H-index: 129

North America-United States

About David Bartel

David Bartel, With an exceptional h-index of 129 and a recent h-index of 91 (since 2020), a distinguished researcher at Massachusetts Institute of Technology, specializes in the field of Biology, Gene Regulation, MicroRNAs, Noncoding RNA, Molecular Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Nuclear release of eIF1 globally increases stringency of start-codon selection to preserve mitotic arrest physiology

Control of poly (A)-tail length and translation in vertebrate oocytes and early embryos

ZSWIM8 destabilizes many murine microRNAs and is required for proper embryonic growth and development

A statistical approach for identifying primary substrates of ZSWIM8-mediated microRNA degradation in small-RNA sequencing data

The guide RNA sequence dictates the slicing kinetics and conformational dynamics of the Argonaute silencing complex

The widespread influence of ZSWIM8 on microRNAs during mouse embryonic development

Endogenous transcripts direct microRNA degradation in Drosophila, and this targeted degradation is required for proper embryonic development

The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability

David Bartel Information

University

Position

Professor of Biology HHMI Whitehead Institute

Citations(all)

237209

Citations(since 2020)

65909

Cited By

200486

hIndex(all)

129

hIndex(since 2020)

91

i10Index(all)

219

i10Index(since 2020)

185

Email

University Profile Page

Massachusetts Institute of Technology

Google Scholar

View Google Scholar Profile

David Bartel Skills & Research Interests

Biology

Gene Regulation

MicroRNAs

Noncoding RNA

Molecular Biology

Top articles of David Bartel

Title

Journal

Author(s)

Publication Date

Nuclear release of eIF1 globally increases stringency of start-codon selection to preserve mitotic arrest physiology

bioRxiv

Jimmy Ly

Kehui Xiang

Kuan-Chung Su

Gunter B Sissoko

David P Bartel

...

2024

Control of poly (A)-tail length and translation in vertebrate oocytes and early embryos

bioRxiv

Kehui Xiang

Jimmy Ly

David Bartel

2023

ZSWIM8 destabilizes many murine microRNAs and is required for proper embryonic growth and development

Genome Research

Charlie Y Shi

Lara E Elcavage

Raghu R Chivukula

Joanna Stefano

Benjamin Kleaveland

...

2023/9/1

A statistical approach for identifying primary substrates of ZSWIM8-mediated microRNA degradation in small-RNA sequencing data

BMC Bioinformatics

PY Wang

DP Bartel

2023/5/12

The guide RNA sequence dictates the slicing kinetics and conformational dynamics of the Argonaute silencing complex

bioRxiv

Peter Y Wang

David P Bartel

2023

The widespread influence of ZSWIM8 on microRNAs during mouse embryonic development

bioRxiv

Charlie Shi

Lara Elcavage

Raghu Chivukula

Joanna Stefano

Benjamin Kleaveland

...

2023

Endogenous transcripts direct microRNA degradation in Drosophila, and this targeted degradation is required for proper embryonic development

Molecular cell

Elena R Kingston

Lianne W Blodgett

David P Bartel

2022/10/20

The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability

Cell

Erinc Hallacli

Can Kayatekin

Sumaiya Nazeen

Xiou H Wang

Zoe Sheinkopf

...

2022/6/9

The interplay between translational efficiency, poly (A) tails, microRNAs, and neuronal activation

RNA

Timothy J Eisen

Jingyi Jessica Li

David P Bartel

2022/6/1

MicroRNA 3′-compensatory pairing occurs through two binding modes, with affinity shaped by nucleotide identity and position

eLife

Sean E McGeary

Namita Bisaria

Thy M Pham

Peter Y Wang

David P Bartel

2022/2/22

RNA: Author Index for Volume 28, 2022

RNA

B Addepalli

M Akeson

H Alalam

S Almeida

AN Amorello

...

2022

Increasing RNAi efficiency through single nucleotide mismatches

2021/12/28

RNA: Author Index for Volume 27, 2021

RNA

L Abdullahu

PL Abreu

F Aguilo

NS Ahmed

BM Akiyama

...

2021

Degradation of host translational machinery drives tRNA acquisition in viruses

Cell Systems

Joy Y Yang

Wenwen Fang

Fabiola Miranda-Sanchez

Julia M Brown

Kathryn M Kauffman

...

2021/8/18

The molecular basis of coupling between poly (A)-tail length and translational efficiency

Elife

Kehui Xiang

David P Bartel

2021/7/2

Ago2 protects Drosophila siRNAs and microRNAs from target-directed degradation, even in the absence of 2′-O-methylation

Rna

Elena R Kingston

David P Bartel

2021/6/1

Pairing to the microRNA 3′ region occurs through two alternative binding modes, with affinity shaped by nucleotide identity as well as pairing position

BioRxiv

Sean E McGeary

Namita Bisaria

David P Bartel

2021/4/14

MicroRNA clustering assists processing of suboptimal microRNA hairpins through the action of the ERH protein

Molecular Cell

Wenwen Fang

David P. Bartel

2020

MicroRNAs cause accelerated decay of short-tailed target mRNAs

Molecular Cell

Timothy J Eisen

Stephen W Eichhorn

Alexander O Subtelny

David P Bartel

2020/2/20

The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation

Science

Charlie Y Shi

Elena R Kingston

Benjamin Kleaveland

Daniel H Lin

Michael W Stubna

...

2020/12/18

See List of Professors in David Bartel University(Massachusetts Institute of Technology)