Darrell J. Irvine

Darrell J. Irvine

Massachusetts Institute of Technology

H-index: 101

North America-United States

About Darrell J. Irvine

Darrell J. Irvine, With an exceptional h-index of 101 and a recent h-index of 74 (since 2020), a distinguished researcher at Massachusetts Institute of Technology, specializes in the field of Immune Engineering.

His recent articles reflect a diverse array of research interests and contributions to the field:

Glycan-costumed virus-like particles promote type 1 anti-tumor immunity

Compositions for chimeric antigen receptor t cell therapy and uses thereof

Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity

Synthetic oncolytic lnp-replicon rna and uses for cancer immunotherapy

LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing

Layer-by-layer nanoparticles for cytokine therapy in cancer treatment

Modulating antigen availability in lymphoid organs to shape the humoral immune response to vaccines

Methods and compositions for heterologous repRNA immunizations

Darrell J. Irvine Information

University

Position

___

Citations(all)

35824

Citations(since 2020)

19699

Cited By

23891

hIndex(all)

101

hIndex(since 2020)

74

i10Index(all)

254

i10Index(since 2020)

222

Email

University Profile Page

Massachusetts Institute of Technology

Google Scholar

View Google Scholar Profile

Darrell J. Irvine Skills & Research Interests

Immune Engineering

Top articles of Darrell J. Irvine

Title

Journal

Author(s)

Publication Date

Glycan-costumed virus-like particles promote type 1 anti-tumor immunity

bioRxiv

Valerie Lensch

Adele Gabba

Robert Hincapie

Sachin H Bhagchandani

Ankit Basak

...

2024

Compositions for chimeric antigen receptor t cell therapy and uses thereof

2020/7/29

Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity

bioRxiv

Luciano Santollani

Yiming J Zhang

Laura Maiorino

Joseph R Palmeri

Jordan A Stinson

...

2024

Synthetic oncolytic lnp-replicon rna and uses for cancer immunotherapy

2024/1/25

LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing

Nature Communications

Yonger Xue

Yuebao Zhang

Yichen Zhong

Shi Du

Xucheng Hou

...

2024/1/25

Layer-by-layer nanoparticles for cytokine therapy in cancer treatment

2023/6/29

Modulating antigen availability in lymphoid organs to shape the humoral immune response to vaccines

Aereas Aung

Darrell J Irvine

2024/1/15

Methods and compositions for heterologous repRNA immunizations

2022/4/14

Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells

bioRxiv

Leyuan Ma

Ranjani Ramasubramanian

Naveen Mehta

Benjamin Cossette

Duncan Morgan

...

2024

ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK. CAR-T cells

Cancer cell

Elisa Bergaggio

Wei-Tien Tai

Andrea Aroldi

Carmen Mecca

Elisa Landoni

...

2023/12/11

Elucidating Vaccine Trafficking Mechanisms using Multimodal Imaging

Brittany L Hartwell

Jacob Martin

Jason YH Chang

Sidath C Kumarapperuma

Ruth M Ruprecht

...

2023/8/1

Optimization of an alum-anchored clinical HIV vaccine candidate

npj Vaccines

Kristen A Rodrigues

Christopher A Cottrell

Jon M Steichen

Bettina Groschel

Wuhbet Abraham

...

2023/8/12

Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells

ACS Central Science

Nicholas L Truex

Aurélie Rondon

Simon L Rössler

Cameron C Hanna

Yehlin Cho

...

2023/9/14

Low protease activity in B cell follicles promotes retention of intact antigens after immunization

Science

Aereas Aung

Ang Cui

Laura Maiorino

Ava P Amini

Justin R Gregory

...

2023/1/27

A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates

Nature Communications

Ivy Phung

Kristen A Rodrigues

Ester Marina-Zárate

Laura Maiorino

Bapi Pahar

...

2023/11/4

Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors

Bioengineering & Translational Medicine

Antonio E Barberio

Sean G Smith

Ivan S Pires

Sonia Iyer

Ferenc Reinhardt

...

2023/3

Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation

Science Advances

Sachin H Bhagchandani

Farrukh Vohidov

Lauren E Milling

Evelyn Yuzhou Tong

Christopher M Brown

...

2023/4/19

Progress in vaccine development for infectious diseases—a Keystone Symposia report

Annals of the New York Academy of Sciences

Jennifer Cable

Barney S Graham

Richard A Koup

Robert A Seder

Katalin Karikó

...

2023/6

Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

Cell

Leyuan Ma

Alexander Hostetler

Duncan M Morgan

Laura Maiorino

Ina Sulkaj

...

2023/7/20

Albumin binding peptide conjugates and methods thereof

2023/8/10

See List of Professors in Darrell J. Irvine University(Massachusetts Institute of Technology)

Co-Authors

H-index: 96
Todd M. Allen

Todd M. Allen

Harvard University

H-index: 74
Francesco Stellacci

Francesco Stellacci

École Polytechnique Fédérale de Lausanne

H-index: 72
J. Christopher Love

J. Christopher Love

Massachusetts Institute of Technology

H-index: 63
Florencia Pereyra

Florencia Pereyra

Harvard University

H-index: 55
James Moon

James Moon

University of Michigan-Dearborn

academic-engine