Daniel Siegwart
University of Texas Southwestern Medical Center
H-index: 48
North America-United States
Top articles of Daniel Siegwart
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Unsaturated dendrimers compositions, related formulations, and methods of use thereof | 2024/4/18 | ||
Lipocationic dendrimers and uses thereof | 2024/2/8 | ||
Compositions and methods for modulating gene or gene product in cells | 2024/1/2 | ||
In vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration | Hepatology | Yu-Hsuan Lin Qiyu Zeng Yuemeng Jia Zixi Wang Lin Li | 2023/10/1 |
Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs | Sean A Dilliard Daniel J Siegwart | 2023/4 | |
Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models | Nature communications | Tuo Wei Yehui Sun Qiang Cheng Sumanta Chatterjee Zachary Traylor | 2023/11/11 |
Compositions and methods for organ specific delivery of nucleic acids | 2023/9/26 | ||
Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery | Xu Wang Shuai Liu Yehui Sun Xueliang Yu Sang M Lee | 2023/1 | |
Compositions and methods for targeted delivery to cells | 2023/10/26 | ||
The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles | Journal of Controlled Release | Sean A Dilliard Yehui Sun Madeline O Brown Yun-Chieh Sung Sumanta Chatterjee | 2023/9/1 |
Spleen SORT LNP Generated in situ CAR T Cells Extend Survival in a Mouse Model of Lymphoreplete B Cell Lymphoma | Angewandte Chemie | Ester Álvarez‐Benedicto Zeru Tian Sumanta Chatterjee Domenico Orlando Minjeong Kim | 2023/10/26 |
Nanotechnology-based mRNA vaccines | Shuying Chen Xiangang Huang Yonger Xue Ester Álvarez-Benedicto Yesi Shi | 2023/8/17 | |
Modular design of biodegradable ionizable lipids for improved mRNA delivery and precise cancer metastasis delineation in vivo | Journal of the American Chemical Society | Zhaoming Chen Yang Tian Jieyu Yang Fapu Wu Senyao Liu | 2023/10/19 |
Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | 2023/6/27 | ||
Functional ionizable phospholipids | 2023/10/12 | ||
In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma | Proceedings of the National Academy of Sciences | Qiang Cheng Lukas Farbiak Amogh Vaidya Erick Guerrero Eunice E Lee | 2023/12/26 |
Disrupting off-target Cas9 activity in the liver | Nature Biomedical Engineering | Sean A Dilliard Daniel J Siegwart | 2022/2 |
Next-Generation Diprovocims with Potent Human and Murine TLR1/TLR2 Agonist Activity That Activate the Innate and Adaptive Immune Response | Journal of medicinal chemistry | Ming-Hsiu Yang Jamie L Russell Yuto Mifune Ying Wang Hexin Shi | 2022/6/29 |
Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA) | Biomaterials science | Ester Álvarez-Benedicto Lukas Farbiak Martha Márquez Ramírez Xu Wang Lindsay T Johnson | 2022 |
An mRNA-Based Therapy to Treat Primary Ciliary Dyskinesia: Aerosol Delivery, Biodistribution and Tolerability | A62 Cystic fibrosis and NON-CF bronchiectasis: mechanistic insights, American Thoracic Society | David Liston Mirko Hennig Daniella Ishimaru Jackson K Eby Shaheen Ahmed | 2022/5/1 |
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