Daniel P. Flaherty

Daniel P. Flaherty

Purdue University

H-index: 18

North America-United States

About Daniel P. Flaherty

Daniel P. Flaherty, With an exceptional h-index of 18 and a recent h-index of 16 (since 2020), a distinguished researcher at Purdue University, specializes in the field of Medicinal Chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Biochemical pharmacology of adenylyl cyclases in cancer

Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1

Novel scaffold of adenylyl cyclase inhibitors for chronic pain and opioid dependence

Altered Protein Dynamics and a More Reactive Catalytic Cysteine in a Neurodegeneration-associated UCHL1 Mutant

Discovery and Validation of a Novel Inhibitor of HYPE-mediated AMPylation

Genetic Determinants of Acinetobacter baumannii Serum-Associated Adaptive Efflux-Mediated Antibiotic Resistance

Protomer selectivity of type II RAF inhibitors within the RAS/RAF complex

Scaffold of adenylyl cyclase inhibitors for chronic pain and opioid dependence

Daniel P. Flaherty Information

University

Position

___

Citations(all)

1044

Citations(since 2020)

771

Cited By

456

hIndex(all)

18

hIndex(since 2020)

16

i10Index(all)

29

i10Index(since 2020)

22

Email

University Profile Page

Purdue University

Google Scholar

View Google Scholar Profile

Daniel P. Flaherty Skills & Research Interests

Medicinal Chemistry

Top articles of Daniel P. Flaherty

Title

Journal

Author(s)

Publication Date

Biochemical pharmacology of adenylyl cyclases in cancer

Bikash Chandra Jena

Daniel P Flaherty

Valerie P O'Brien

Val J Watts

2024/3/24

Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1

Journal of Medicinal Chemistry

Ryan D Imhoff

Rishi Patel

Muhammad Hassan Safdar

Hannah BL Jones

Adan Pinto-Fernandez

...

2024/3/15

Novel scaffold of adenylyl cyclase inhibitors for chronic pain and opioid dependence

2024/3/14

Altered Protein Dynamics and a More Reactive Catalytic Cysteine in a Neurodegeneration-associated UCHL1 Mutant

Journal of Molecular Biology

Sebastian Kenny

Chih-Hsuan Lai

Tsung-Sheng Chiang

Kwame Brown

Chad S Hewitt

...

2024/2/15

Discovery and Validation of a Novel Inhibitor of HYPE-mediated AMPylation

Cell Stress and Chaperones

Ali Camara

Heerak Chugh

Alyssa George

Lukas Dolidze

Kevin Ryu

...

2024/4/9

Genetic Determinants of Acinetobacter baumannii Serum-Associated Adaptive Efflux-Mediated Antibiotic Resistance

Antibiotics

Mikaeel Young

Michaelle Chojnacki

Catlyn Blanchard

Xufeng Cao

William L Johnson

...

2023/7/11

Protomer selectivity of type II RAF inhibitors within the RAS/RAF complex

Cell Chemical Biology

James D Vasta

Ani Michaud

Chad A Zimprich

Michael T Beck

Matthew R Swiatnicki

...

2023/11/16

Scaffold of adenylyl cyclase inhibitors for chronic pain and opioid dependence

2023/6/6

Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate

Cell Chemical Biology

Amanda L Graboski

Mark E Kowalewski

Joshua B Simpson

Xufeng Cao

Mary Ha

...

2023/11/16

Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension

SA Morrisroe

A Gupta

H Tang

T-H Schwantes-An

G Gupta

...

2021/5

Identification of covalent fragment inhibitors for Plasmodium falciparum UCHL3 with anti-malarial efficacy

Bioorganic & Medicinal Chemistry Letters

Ryan D Imhoff

Melissa R Rosenthal

Kutub Ashraf

Purnima Bhanot

Caroline L Ng

...

2023/10/1

Evaluation of 1, 3, 4-thiadiazole carbonic anhydrase inhibitors for gut decolonization of vancomycin-resistant enterococci

ACS Medicinal Chemistry Letters

Nader S Abutaleb

Annadka Shrinidhi

Aloka B Bandara

Mohamed N Seleem

Daniel P Flaherty

2023/3/21

Pyrazolyl pyrimidinone compounds and the uses thereof

2023/8/10

Carbonic Anhydrase Inhibition as a Target for Antibiotic Synergy in Enterococci

Microbiology spectrum

Gayatri Shankar Chilambi

Yu-Hao Wang

Nathan R Wallace

Chetachukwu Obiwuma

Kirsten M Evans

...

2023/8/17

Inhibition of pathogenic bacterial carbonic anhydrases by monothiocarbamates

Journal of Enzyme Inhibition and Medicinal Chemistry

Simone Giovannuzzi

Anil Kumar Marapaka

Nader S Abutaleb

Fabrizio Carta

Hsin-Wen Liang

...

2023/12/31

Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype

Frontiers in pharmacology

Tiffany S Dwyer

Joseph B O’Brien

Christopher P Ptak

Justin E LaVigne

Daniel P Flaherty

...

2022/9/6

Inhibition studies of bacterial α-carbonic anhydrases with phenols

Journal of Enzyme Inhibition and Medicinal Chemistry

Simone Giovannuzzi

Chad S Hewitt

Alessio Nocentini

Clemente Capasso

Gabriele Costantino

...

2022/12/31

Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3

Biomolecules

Chad S Hewitt

Chittaranjan Das

Daniel P Flaherty

2022/1/1

Carbonic anhydrase inhibitors for treatment of neisseria gonorrhoeae infection

2022/7/7

Coumarins effectively inhibit bacterial α-carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry

Simone Giovannuzzi

Chad S Hewitt

Alessio Nocentini

Clemente Capasso

Daniel P Flaherty

...

2022/12/31

See List of Professors in Daniel P. Flaherty University(Purdue University)