Daniel Merk

Daniel Merk

Goethe-Universität Frankfurt am Main

H-index: 30

Europe-Germany

About Daniel Merk

Daniel Merk, With an exceptional h-index of 30 and a recent h-index of 28 (since 2020), a distinguished researcher at Goethe-Universität Frankfurt am Main,

His recent articles reflect a diverse array of research interests and contributions to the field:

Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties

Dual soluble epoxide hydrolase inhibitor–farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis

Functionally-instructed modifiers of response to ATR inhibition in experimental glioma

Rational design and virtual screening identify mimetics of the RXR agonist valerenic acid

A Fluorescence-Based Reporter Gene Assay to Characterize Nuclear Receptor Modulators

Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system

Structural Modification of the Natural Product Valerenic Acid Tunes RXR Homodimer Agonism

De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime

Daniel Merk Information

University

Position

ETH Zurich Switzerland; Germany

Citations(all)

3142

Citations(since 2020)

2734

Cited By

1263

hIndex(all)

30

hIndex(since 2020)

28

i10Index(all)

72

i10Index(since 2020)

64

Email

University Profile Page

Goethe-Universität Frankfurt am Main

Google Scholar

View Google Scholar Profile

Top articles of Daniel Merk

Title

Journal

Author(s)

Publication Date

Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties

Journal of Medicinal Chemistry

Max Lewandowski

Melania Carmina

Loris Knümann

Minh Sai

Sabine Willems

...

2024/1/18

Dual soluble epoxide hydrolase inhibitor–farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis

Frontiers in Immunology

Md Abdul Hye Khan

Benjamin Nolan

Anna Stavniichuk

Daniel Merk

John D Imig

2024/1/3

Functionally-instructed modifiers of response to ATR inhibition in experimental glioma

Journal of Experimental & Clinical Cancer Research

Bianca Walter

Sophie Hirsch

Laurence Kuhlburger

Aaron Stahl

Leonard Schnabel

...

2024/12

Rational design and virtual screening identify mimetics of the RXR agonist valerenic acid

ChemMedChem

Laura Isigkeit

Annette Kärcher

Gustave Adouvi

Silvia Arifi

Daniel Merk

2024/1/18

A Fluorescence-Based Reporter Gene Assay to Characterize Nuclear Receptor Modulators

Espen Schallmayer

Daniel Merk

2023/8/10

Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system

Neuro-Oncology Advances

Mirjam Renovanz

Sylvia C Kurz

Johannes Rieger

Bianca Walter

Hannes Becker

...

2023/1/1

Structural Modification of the Natural Product Valerenic Acid Tunes RXR Homodimer Agonism

ChemMedChem

Daniel Zaienne

Laura Isigkeit

Julian A Marschner

Silke Duensing‐Kropp

Georg Höfner

...

2023/11/2

De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime

Journal of Medicinal Chemistry

Marco Ballarotto

Sabine Willems

Tanja Stiller

Felix Nawa

Julian A Marschner

...

2023/5/31

Check for updates

Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries: 8th International Workshop, BrainLes 2022, Held in Conjunction with MICCAI 2022, Singapore, September 18, 2022, Revised Selected Papers

Segmentation Framework via Optimal

Mass Transportation Pre-processing

Jia-Wei Liao¹

Tsung-Ming Huang

Tiexiang Li

...

2023/7/17

An Introduction to Chemogenomics

Apirat Chaikuad

Daniel Merk

2023/8/10

State-of-the-art methodological investigation of carotenoid activity and metabolism–from organic synthesis via metabolism to biological activity–exemplified by a novel retinoid …

Torsten Bohn

Angel R de Lera

Jean-Francois Landrier

Harald Carlsen

Daniel Merk

...

2023

Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole

Journal of Medicinal Chemistry

Minh Sai

Jan Vietor

Moritz Kornmayer

Markus Egner

Úrsula López-García

...

2023/9/26

Illuminating the druggable genome through patent bioactivity data

PeerJ

Maria P Magariños

Anna Gaulton

Eloy Félix

Tevfik Kiziloren

Ricardo Arcila

...

2023/5/2

Check Chapter 3 updates

Xylem: Methods and Protocols

Alex Tavkhelidze

Gerhard Buck-Sorlin

Winfried Kurth

2023/10/28

Compilation of Custom Compound/Bioactivity Datasets from Public Repositories

Laura Isigkeit

Daniel Merk

2023/8/10

Development of a Potent Nurr1 Agonist Tool for in Vivo Applications

Journal of Medicinal Chemistry

Jan Vietor

Christian Gege

Tanja Stiller

Romy Busch

Espen Schallmayer

...

2023/4/26

Deep interactome learning for de novo drug design

Kenneth Atz

Leandro Cotos Muñoz

Clemens Isert

Maria Håkansson

Dorota Focht

...

2023/9/19

Light-controlled inhibition of the circadian regulator RORγ

Martin Reynders

Sabine Willems

Julian A Marschner

Thomas Wein

Daniel Merk

...

2023/7/31

Structure-guided design of a highly potent RXR agonist with superior physicochemical properties

Max Lewandowski

Melania Carmina

Loris Knümann

Minh Sai

Sabine Willems

...

2023/12/12

P10. 25. A ATR INHIBITION IN EXPERIMENTAL GLIOMA: DISCOVERY AND VALIDATION OF MOLECULAR TARGETS FOR FUNCTIONALLY-INSTRUCTED COMBINATION THERAPIES

Neuro-Oncology

B Walter

S Hirsch

L Kuhlburger

A Stahl

L Schnabel

...

2023/9/1

See List of Professors in Daniel Merk University(Goethe-Universität Frankfurt am Main)