Craig A. Townsend

Craig A. Townsend

Johns Hopkins University

H-index: 68

North America-United States

About Craig A. Townsend

Craig A. Townsend, With an exceptional h-index of 68 and a recent h-index of 33 (since 2020), a distinguished researcher at Johns Hopkins University, specializes in the field of Bioorganic Chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

The dabABC operon is a marker of C4-alkylated monobactam biosynthesis and responsible for (2S, 3R)-diaminobutyrate production

The structure of the monobactam-producing thioesterase domain of SulM forms a unique complex with the upstream carrier protein domain

Synthesis of functionalized 2, 3-diaminopropionates and their potential for directed monobactam biosynthesis

Dynemicin A Derivatives as Potential Cancer Chemotherapeutics by Mutasynthesis

Targeted Discovery of Cryptic Enediyne Natural Products via FRET-Coupled High-Throughput Elicitor Screening

Normal and Aberrant Methyltransferase Activities Give Insights into the Final Steps of Dynemicin A Biosynthesis

Colorimetric determination of adenylation domain activity in nonribosomal peptide synthetases by using chrome azurol s

Examining Heterodimerization by Aryl C–N Coupling in Dynemicin Biosynthesis

Craig A. Townsend Information

University

Position

A. H. Corwin Professor of Chemistry

Citations(all)

17522

Citations(since 2020)

3897

Cited By

14923

hIndex(all)

68

hIndex(since 2020)

33

i10Index(all)

235

i10Index(since 2020)

100

Email

University Profile Page

Johns Hopkins University

Google Scholar

View Google Scholar Profile

Craig A. Townsend Skills & Research Interests

Bioorganic Chemistry

Top articles of Craig A. Townsend

Title

Journal

Author(s)

Publication Date

The dabABC operon is a marker of C4-alkylated monobactam biosynthesis and responsible for (2S, 3R)-diaminobutyrate production

iScience

Rongfeng Li

Michael S Lichstrahl

Trevor A Zandi

Lukas Kahlert

Craig A Townsend

2024/2/12

The structure of the monobactam-producing thioesterase domain of SulM forms a unique complex with the upstream carrier protein domain

bioRxiv

Ketan D Patel

Ryan A Oliver

Michael S Lichstrahl

Rongfeng Li

Craig A Townsend

...

2024

Synthesis of functionalized 2, 3-diaminopropionates and their potential for directed monobactam biosynthesis

Chemical Science

Michael S Lichstrahl

Lukas Kahlert

Rongfeng Li

Trevor A Zandi

Jerry Yang

...

2023

Dynemicin A Derivatives as Potential Cancer Chemotherapeutics by Mutasynthesis

Helvetica Chimica Acta

Paramita Pal

Jamie R Alley

Douglas R Cohen

Craig A Townsend

2023/12

Targeted Discovery of Cryptic Enediyne Natural Products via FRET-Coupled High-Throughput Elicitor Screening

ACS chemical biology

Esther J Han

Seoung Rak Lee

Craig A Townsend

Mohammad R Seyedsayamdost

2023/7/18

Normal and Aberrant Methyltransferase Activities Give Insights into the Final Steps of Dynemicin A Biosynthesis

Journal of the American Chemical Society

Paramita Pal

Serena ML Wessely

Craig A Townsend

2023/6/5

Colorimetric determination of adenylation domain activity in nonribosomal peptide synthetases by using chrome azurol s

ChemBioChem

Lukas Kahlert

Michael S Lichstrahl

Craig A Townsend

2023/3/1

Examining Heterodimerization by Aryl C–N Coupling in Dynemicin Biosynthesis

ACS Chemical Biology

Paramita Pal

Jamie R Alley

Craig A Townsend

2023/1/25

Sea Urchin polyketide synthase SpPks1 produces the naphthalene precursor to echinoderm pigments

Journal of the American Chemical Society

Feng Li

Zhenjian Lin

Joshua P Torres

Eric A Hill

Dehai Li

...

2022/5/19

ThnL, a B12-dependent radical S-adenosylmethionine enzyme, catalyzes thioether bond formation in carbapenem biosynthesis

Proceedings of the National Academy of Sciences

Erica K Sinner

Rongfeng Li

Daniel R Marous

Craig A Townsend

2022/8/23

Penicillin binding proteins and β-lactamases of Mycobacterium tuberculosis: reexamination of the historical paradigm

MSphere

Gaurav Kumar

Christos Galanis

Hunter R Batchelder

Craig A Townsend

Gyanu Lamichhane

2022/2/23

Structure–Activity Relationship of Penem Antibiotic Side Chains Used against Mycobacteria Reveals Highly Active Compounds

ACS infectious diseases

Hunter R Batchelder

Trevor A Zandi

Amit Kaushik

Akul Naik

Elizabeth Story-Roller

...

2022/8/2

Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis

Nature

Hayley L Knox

Erica K Sinner

Craig A Townsend

Amie K Boal

Squire J Booker

2022/2/10

Stereochemical course of cobalamin-dependent radical SAM methylation by TokK and ThnK

RSC Chemical Biology

Michael S Lichstrahl

Craig A Townsend

Erica K Sinner

2022

Accurate Substrate-Like Probes for Trapping Late-Stage Intermediates in Nonribosomal Peptide Synthetase Condensation Domains

ACS chemical biology

Michael J Wheadon

Craig A Townsend

2022/8/1

Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in carbapenem β-lactam antibiotic biosynthesis

Erica K Sinner

Craig A Townsend

2022/1/1

T405, a New Penem, Exhibits In Vivo Efficacy against M. abscessus and Synergy with β-Lactams Imipenem and Cefditoren

Antimicrobial agents and chemotherapy

Binayak Rimal

Hunter R Batchelder

Elizabeth Story-Roller

Chandra M Panthi

Chavis Tabor

...

2022/6/21

Acyl donor stringency and dehydroaminoacyl intermediates in β-lactam formation by a non-ribosomal peptide synthetase

ACS chemical biology

Darcie H Long

Craig A Townsend

2021/4/13

Evolution of methods for the study of Cobalamin-dependent radical SAM enzymes

ACS bio & med chem Au

Erica K Sinner

Daniel R Marous

Craig A Townsend

2021/10/13

Direct Deoxygenative Intramolecular Acylation of Biarylcarboxylic Acids

Synlett

Yantao Li

Wentao Xu

Chengjian Zhu

Jin Xie

2021/3

See List of Professors in Craig A. Townsend University(Johns Hopkins University)