Claudiu Gradinaru

Claudiu Gradinaru

University of Toronto

H-index: 32

North America-Canada

About Claudiu Gradinaru

Claudiu Gradinaru, With an exceptional h-index of 32 and a recent h-index of 19 (since 2020), a distinguished researcher at University of Toronto, specializes in the field of biophysics, single-molecule fluorescence, intrinsically disordered proteins, G protein coupled receptors.

His recent articles reflect a diverse array of research interests and contributions to the field:

Diffusion and Oligomerization States of the Muscarinic M1 Receptor in Live Cells─The Impact of Ligands and Membrane Disruptors

PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins

Local disordered region sampling (LDRS) for ensemble modeling of proteins with experimentally undetermined or low confidence prediction segments

Delineating structural propensities of the 4E-BP2 protein via integrative modeling and clustering

Dissecting diffusion and oligomerization dynamics of GPCRs in live cells using single-particle tracking

Beyond disorder: An integrative investigation of the intrinsically disordered protein 4E-BP2

Multimodal interactions between a disordered protein and its folded target at single-molecule level

Multisite phosphorylation and binding alter conformational dynamics of the 4E-BP2 protein

Claudiu Gradinaru Information

University

Position

Professor of Physics

Citations(all)

3330

Citations(since 2020)

1228

Cited By

2574

hIndex(all)

32

hIndex(since 2020)

19

i10Index(all)

56

i10Index(since 2020)

32

Email

University Profile Page

University of Toronto

Google Scholar

View Google Scholar Profile

Claudiu Gradinaru Skills & Research Interests

biophysics

single-molecule fluorescence

intrinsically disordered proteins

G protein coupled receptors

Top articles of Claudiu Gradinaru

Title

Journal

Author(s)

Publication Date

Diffusion and Oligomerization States of the Muscarinic M1 Receptor in Live Cells─The Impact of Ligands and Membrane Disruptors

The Journal of Physical Chemistry B

Xiaohan Zhou

Horacio Septien-Gonzalez

Sami Husaini

Richard J Ward

Graeme Milligan

...

2024/3/18

PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins

Nucleic acids research

Hamidreza Ghafouri

Tamas Lazar

Alessio Del Conte

Luiggi G Tenorio Ku

Peter Tompa

...

2024/1/5

Local disordered region sampling (LDRS) for ensemble modeling of proteins with experimentally undetermined or low confidence prediction segments

Bioinformatics

Zi Hao Liu

João MC Teixeira

Oufan Zhang

Thomas E Tsangaris

Jie Li

...

2023/12/1

Delineating structural propensities of the 4E-BP2 protein via integrative modeling and clustering

The Journal of Physical Chemistry B

Thomas E Tsangaris

Spencer Smyth

Gregory-Neal W Gomes

Zi Hao Liu

Moses Milchberg

...

2023/8/18

Dissecting diffusion and oligomerization dynamics of GPCRs in live cells using single-particle tracking

Biophysical Journal

Xiaohan Zhou

Claudiu C Gradinaru

2023/2/10

Beyond disorder: An integrative investigation of the intrinsically disordered protein 4E-BP2

Biophysical Journal

Thomas E Tsangaris

Spencer Smyth

Greg W Gomes

Julie D Forman-Kay

Claudiu C Gradinaru

2023/2/10

Multimodal interactions between a disordered protein and its folded target at single-molecule level

Biophysical Journal

Spencer Smyth

Claudiu C Gradinaru

Julie D Forman-Kay

2023/2/10

Multisite phosphorylation and binding alter conformational dynamics of the 4E-BP2 protein

Biophysical Journal

Spencer Smyth

Zhenfu Zhang

Alaji Bah

Thomas E Tsangaris

Jennifer Dawson

...

2022/8/16

Integrative conformational ensembles of Sic1 using different initial pools and optimization methods

Frontiers in Molecular Biosciences

Gregory-Neal W Gomes

Ashley Namini

Claudiu C Gradinaru

2022/7/18

Protein dynamics to define and refine disordered protein ensembles

The Journal of Physical Chemistry B

Pavithra M Naullage

Mojtaba Haghighatlari

Ashley Namini

João MC Teixeira

Jie Li

...

2022/2/25

A research

Zahraa Saad Abd Ali

2022

Single-molecule counting applied to the study of GPCR oligomerization

Joshua N Milstein

Daniel F Nino

Xiaohan Zhou

Claudiu C Gradinaru

2022/9/6

Integrating NMR, SAXS and Single-Molecule FRET Data to Infer Conformational Ensembles of the Yeast Sic1 Protein

Biophysical Journal

Claudiu C Gradinaru

Gregory W Gomes

Tanja Mittag

Teresa L Head-Gordon

Julie D Forman-Kay

2021/2/12

Measuring Conformational Selection in G Protein-Coupled Receptors by Single-Molecule Förster Resonance Energy Transfer

Ivonne Lopez-Miranda

Dennis Fernandes

Omar Almurad

Yevgen Moskalenko

R Scott Prosser

...

2021/5/27

Single-Step, Single-Column Protein Purification and Labelling for Fluorescence Studies

Biophysical Journal

Arvi Puka

Adrian Rotaru

Spencer Smyth

Andrew Beharry

Claudiu C Gradinaru

2021/2/12

Multifunctional nanoparticles as theranostic agents for therapy and imaging of breast cancer

Journal of Photochemistry and Photobiology B: Biology

Donald A Fernandes

Dennis D Fernandes

Aimen Malik

Gregory-Neal W Gomes

Sila Appak-Baskoy

...

2021/5/1

PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins

Nucleic acids research

Tamas Lazar

Elizabeth Martínez-Pérez

Federica Quaglia

András Hatos

Lucía B Chemes

...

2021/1/8

Ligand modulation of the conformational dynamics of the A2A adenosine receptor revealed by single-molecule fluorescence

Scientific reports

Dennis D Fernandes

Chris Neale

Gregory-Neal W Gomes

Yuchong Li

Aimen Malik

...

2021/3/15

Modelling the Multifarious Conformations of the Intrinsically Disordered Protein 4E-BP2 with sm-FRET, SAXS & PRE Restraints

Biophysical Journal

Spencer Smyth

Thomas Tsangaris

Alaji Bah

Julie D Forman-Kay

Claudiu C Gradinaru

2021/2/12

Probing Allostery in Oligomeric M2 Receptors using smFRET

Biophysical Journal

Dennis D Fernandes

Aimen Malik

Claudiu C Gradinaru

2021/2/12

See List of Professors in Claudiu Gradinaru University(University of Toronto)

Co-Authors

H-index: 114
Rienk van Grondelle

Rienk van Grondelle

Vrije Universiteit Amsterdam

H-index: 91
Julie D Forman-Kay

Julie D Forman-Kay

University of Toronto

H-index: 83
Ivo HM van Stokkum

Ivo HM van Stokkum

Vrije Universiteit Amsterdam

H-index: 70
Herbert van Amerongen

Herbert van Amerongen

Wageningen Universiteit

H-index: 67
Hue Sun Chan

Hue Sun Chan

University of Toronto

H-index: 56
Erwin Peterman

Erwin Peterman

Vrije Universiteit Amsterdam

academic-engine