Christopher C. W. Hughes

Christopher C. W. Hughes

University of California, Irvine

H-index: 69

North America-United States

About Christopher C. W. Hughes

Christopher C. W. Hughes, With an exceptional h-index of 69 and a recent h-index of 46 (since 2020), a distinguished researcher at University of California, Irvine, specializes in the field of vascular biology, bioengineering, tumor microenvironment.

His recent articles reflect a diverse array of research interests and contributions to the field:

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction

SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system

Targeting tumor–stromal interactions in triple-negative breast cancer using a human vascularized micro-tumor model

A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions

CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo

Fundamental considerations for designing endothelialized in vitro models of thrombosis

Image analysis process of microphysiological systems

Microfluidic pressure regulator for robust hydrogel loading without bursting

Christopher C. W. Hughes Information

University

Position

___

Citations(all)

21767

Citations(since 2020)

7811

Cited By

16928

hIndex(all)

69

hIndex(since 2020)

46

i10Index(all)

121

i10Index(since 2020)

85

Email

University Profile Page

University of California, Irvine

Google Scholar

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Christopher C. W. Hughes Skills & Research Interests

vascular biology

bioengineering

tumor microenvironment

Top articles of Christopher C. W. Hughes

Title

Journal

Author(s)

Publication Date

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction

Biofabrication

R Hugh F Bender

Benjamen T O’Donnell

Bhupinder Shergill

Brittany Q Pham

Sima Tahmouresie

...

2024/1/11

SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system

Frontiers in Cardiovascular Medicine

Christopher J Hatch

Sebastian D Piombo

Jennifer S Fang

Johannes S Gach

Makena L Ewald

...

2024/3/21

Targeting tumor–stromal interactions in triple-negative breast cancer using a human vascularized micro-tumor model

Breast Cancer Research

Stephanie J Hachey

Christopher J Hatch

Daniela Gaebler

Aneela Mocherla

Kevin Nee

...

2024/1/5

A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions

bioRxiv

Jennifer Fang

Christopher J Hatch

Jillian Andrejecsk

William Van Trigt

Damie J Juat

...

2024/3/12

CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo

bioRxiv

Linh M Vuong

Stephanie J Hachey

Jessica Shiu

Danny Fei Xie

Noel Salvador

...

2024

Fundamental considerations for designing endothelialized in vitro models of thrombosis

Titus P Lemmens

Vanessa Bröker

Minke Rijpkema

Christopher CW Hughes

Leon J Schurgers

...

2024/3/5

Image analysis process of microphysiological systems

2024/2/22

Microfluidic pressure regulator for robust hydrogel loading without bursting

2024/2/13

Single-cell transcriptomic analysis of partial endothelial-to-mesenchymal transition in sprouting angiogenesis

Cancer Research

Kapil Thapa

Christopher J Hatch

Christopher Hughes

Jennifer S Fang

2024/3/22

Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research

JoVE (Journal of Visualized Experiments)

Stephanie J Hachey

Daniela Gaebler

Christopher CW Hughes

2023/9/15

Plasma exosome gene signature differentiates colon cancer from healthy controls

Annals of surgical oncology

Paul A Vallejos

Amber Gonda

Jingjing Yu

Brittany G Sullivan

Arsha Ostowari

...

2023/6

Establishing a physiologic human vascularized micro-tumor model for cancer research

JoVE (Journal of Visualized Experiments)

Stephanie J Hachey

Daniela Gaebler

Christopher CW Hughes

2023/9/15

A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease

Translational Research

Stephanie J Hachey

Agua Sobrino

John G Lee

Mehraneh D Jafari

Samuel J Klempner

...

2023/5/1

Ovarian Cancer Patient-Derived Organoid Models for Pre-Clinical Drug Testing

JoVE (Journal of Visualized Experiments)

Bisiayo E Fashemi

Lillian van Biljon

Jeimmy Rodriguez

Olivia Graham

Mary Mullen

...

2023/9/15

1.7-micron optical coherence tomography angiography (OCTA) for characterization of hereditary hemorrhagic telangiectasia (HHT) lesions

Raksha Sreeramachandra Murthy

Rachel Elsanadi

Yan Li

John Soliman

Li-Dek Chou

...

2023/3/9

OPEN ACCESS EDITED BY

Community Series-Extremophiles: Microbial Genomics and Taxogenomics, Volume II

José Luis Losada

Asier Gonzalez-Artetxe

Yousri Elghoul

Júlio A Costa

JA Costa

...

2023/11/22

Cx40 Suppresses Sprouting Angiogenesis In Vitro

Bioelectricity

Edward K Looker

Femke J Aan

Christopher J Hatch

Christopher CW Hughes

Michelle L Matter

...

2023/12/1

Exosomes as a source of biomarkers for gastrointestinal cancers

Jingjing Yu

Arsha Ostowari

Amber Gonda

Kiarash Mashayekhi

Farshid Dayyani

...

2023/2/16

ASO Visual Abstract: Plasma Exosome Gene Signature Differentiates Colon Cancer from Healthy Controls

Annals of surgical oncology

Paul A Vallejos

Amber Gonda

Jingjing Yu

Brittany G Sullivan

Arsha Ostowari

...

2023/6

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

The Lancet Diabetes & Endocrinology

O Abani

A Abbas

F Abbas

J Abbas

K Abbas

...

2023/12/1

See List of Professors in Christopher C. W. Hughes University(University of California, Irvine)