Christian Brendel
Harvard University
H-index: 27
North America-United States
Top articles of Christian Brendel
A Novel High-Titer, Bifunctional Lentiviral Vector for Autologous Hematopoietic Stem Cell Gene Therapy of Sickle Cell Disease
Molecular Therapy Methods & Clinical Development
2024/4/24
Boya Liu
H-Index: 0
Christian Brendel
H-Index: 19
Abstract NG05: Epitope editing enables targeted immunotherapy of acute myeloid leukemia
Cancer Research
2024/4/5
Jing Zeng
H-Index: 21
Christian Brendel
H-Index: 19
Alessandro Rambaldi
H-Index: 71
Jerome Ritz
H-Index: 65
Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia
Blood
2023/11/28
Jing Zeng
H-Index: 21
Scott Ficarro
H-Index: 40
Christian Brendel
H-Index: 19
Alessandro Rambaldi
H-Index: 71
Jerome Ritz
H-Index: 65
UM171 Enhances Fitness and Engraftment of Gene Modified Hematopoietic Stem Cells from Sickle Cells Disease Patients
Blood
2023/11/28
Epitope Edited Hematopoietic Stem Cells Allow Immune-Based In Vivo Selection of Genome-Engineered Cells
Blood
2023/11/28
Jing Zeng
H-Index: 21
Christian Brendel
H-Index: 19
237 Epitope engineered hematopoietic stem cells to enable multi-specificity CAR-T cells for acute myeloid leukemia
2023/11/1
Jing Zeng
H-Index: 21
Christian Brendel
H-Index: 19
Jerome Ritz
H-Index: 65
Scott Ficarro
H-Index: 40
Daniel Bauer
H-Index: 1
Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling
Nature Communications
2023/9/20
Epitope editing enables targeted immunotherapy of acute myeloid leukaemia
Nature
2023/9/14
Jing Zeng
H-Index: 21
Christian Brendel
H-Index: 19
Alessandro Rambaldi
H-Index: 71
Jerome Ritz
H-Index: 65
Swapping the serotype: A novel helper-dependent adenoviral vector platform for in vivo HSC gene therapy
Molecular Therapy-Methods & Clinical Development
2023/9/14
Christian Brendel
H-Index: 19
Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells
BioRxiv
2023
Deletion of murine Rhoh leads to de-repression of Bcl-6 via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma
Small GTPases
2022/12/31
Felicia Ciuculescu
H-Index: 7
Qiuming Yao
H-Index: 16
Chad Harris
H-Index: 2
Christian Brendel
H-Index: 19
Roberto Chiarle
H-Index: 32
Targeting a Putative Intronic Splicing Silencer Salvages Expression from the Recurrent SBDS C. 258+ 2T> C Mutant Allele in Shwachman-Diamond Syndrome Patient Cells and Mouse Model
Blood
2022/11/15
Therapeutic Gene Editing of HSCs Ex Vivo without in Vitro Culture Avoids Genotoxicity, Simplifies Procedures, and Preserves Efficiency and Stemness
Blood
2022/11/15
Jing Zeng
H-Index: 21
Linda Yingqi Lin
H-Index: 2
Archana Verma
H-Index: 3
Christian Brendel
H-Index: 19
Luca Pinello
H-Index: 32
Combining the Anti-Sickling βAS3-Globin Gene with BCL11A and ZNF410 Double Shmirs for the Treatment of Sickle Cell Disease
Blood
2022/11/15
Boya Liu
H-Index: 0
Christian Brendel
H-Index: 19
Induction of fetal hemoglobin and reduction of clinical manifestations in patients with severe sickle cell disease treated with shmir-based lentiviral gene therapy for post …
Blood
2022/11/15
Epitope Engineered Hematopoietic Stem and Progenitor Cells to Enable CAR-T Cell Immunotherapy for Acute Myeloid Leukemia
American Society of Hematology Annual Meeting
2022/11/15
Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies
Molecular Therapy
2022/8/3
Boya Liu
H-Index: 0
Christian Brendel
H-Index: 19
Divya S Vinjamur
H-Index: 8
Yu Zhou
H-Index: 21
Chad Harris
H-Index: 2
Hematopoietic Stem/Progenitor Cells and Engineering: FROM HARMFUL TO USEFUL: EXPLOITING A LEUKEMIC TRANSCRIPTION FACTOR FOR LARGE-SCALE EX VIVO MANUFACTURE OF HUMAN MACROPHAGES
Cytotherapy
2022/5/1
Combined+ 58 and+ 55 BCL11A enhancer editing Yields exceptional efficiency, specificity and HbF induction in human and NHP preclinical models
Blood
2021/11/23
Restored macrophage function ameliorates disease pathophysiology in a mouse model for IL10 receptor-deficient very early onset inflammatory bowel disease
Journal of Crohn's and Colitis
2021/9/1
Christian Brendel
H-Index: 19
