Ching Chiek Koh, Gene

About Ching Chiek Koh, Gene

Ching Chiek Koh, Gene, With an exceptional h-index of 18 and a recent h-index of 17 (since 2020), a distinguished researcher at University of Cambridge, specializes in the field of Cancer Genomics, CRISPR/Cas9 gene/genome editing, Immunopeptidomics, Computational and Synthetic Biology, DNA/DSB repair.

His recent articles reflect a diverse array of research interests and contributions to the field:

Genetic interaction library screening with a next-generation dual guide CRISPR system

The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells

A rare genetic disorder provides insights into mechanisms of early-onset neurodegeneration

Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells

All driven by energy demand? Integrative comparison of metabolism of Enterococcus faecalis wildtype and a glutamine synthase mutant

Substitution mutational signatures in whole-genome–sequenced cancers in the UK population

FANCD2-associated nuclease 1 partially compensates for the lack of exonuclease 1 in mismatch repair

Mutational signatures: emerging concepts, caveats and clinical applications

Ching Chiek Koh, Gene Information

University

Position

Wellcome Trust Sanger Institute

Citations(all)

2418

Citations(since 2020)

1863

Cited By

1110

hIndex(all)

18

hIndex(since 2020)

17

i10Index(all)

20

i10Index(since 2020)

20

Email

University Profile Page

Google Scholar

Ching Chiek Koh, Gene Skills & Research Interests

Cancer Genomics

CRISPR/Cas9 gene/genome editing

Immunopeptidomics

Computational and Synthetic Biology

DNA/DSB repair

Top articles of Ching Chiek Koh, Gene

Title

Journal

Author(s)

Publication Date

Genetic interaction library screening with a next-generation dual guide CRISPR system

bioRxiv

Thomas Burgold

Emre Karakoc

Emanuel Goncalves

Lisa Dwane

Inigo Barrio-Hernandez

...

2024

The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells

Nature Genetics

Gene Ching Chiek Koh

Soraya Boushaki

Salome Jingchen Zhao

Andrew Marcel Pregnall

Firas Sadiyah

...

2024/1

A rare genetic disorder provides insights into mechanisms of early-onset neurodegeneration

medRxiv

Cherif Badja

Sophie Momen

Gene Ching Cheik Koh

Soraya Boushaki

Theodoros I Roumeliotis

...

2023

Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells

Nature Genetics

Foad J Rouhani

Xueqing Zou

Petr Danecek

Cherif Badja

Tauanne Dias Amarante

...

2022/9

All driven by energy demand? Integrative comparison of metabolism of Enterococcus faecalis wildtype and a glutamine synthase mutant

Microbiology Spectrum

Seyed Babak Loghmani

Eric Zitzow

Gene Ching Chiek Koh

Andreas Ulmer

Nadine Veith

...

2022/4/27

Substitution mutational signatures in whole-genome–sequenced cancers in the UK population

Science

Andrea Degasperi

Xueqing Zou

Tauanne Dias Amarante

Andrea Martinez-Martinez

Gene Ching Chiek Koh

...

2022/4/22

FANCD2-associated nuclease 1 partially compensates for the lack of exonuclease 1 in mismatch repair

Molecular and Cellular Biology

Katja Kratz

Mariela Artola-Borán

Saho Kobayashi-Era

Gene Koh

Goncalo Oliveira

...

2021/9/1

Mutational signatures: emerging concepts, caveats and clinical applications

Gene Koh

Andrea Degasperi

Xueqing Zou

Sophie Momen

Serena Nik-Zainal

2021/10

A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

Nature cancer

Xueqing Zou

Gene Ching Chiek Koh

Arjun Scott Nanda

Andrea Degasperi

Katie Urgo

...

2021/6

Dissecting mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

BiorXiv

Xueqing Zou

Gene Ching Chiek Koh

Arjun Scott Nanda

Andrea Degasperi

Katie Urgo

...

2020/8/6

Mutational signatures: experimental design and analytical framework

Gene Koh

Xueqing Zou

Serena Nik-Zainal

2020/12

Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts

Nature communications

Ilias Georgakopoulos-Soares

Gene Koh

Sophie E Momen

Josef Jiricny

Martin Hemberg

...

2020/4/24

Direct mutational consequences of CRISPR-cas9 gene-edited DNA repair genes

Cancer Research

Xueqing Zou

Gene Koh

Scott Nanda

Andrea Degasperi

Katie Urgo

...

2020/8/15

A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies

Nature cancer

Andrea Degasperi

Tauanne Dias Amarante

Jan Czarnecki

Scott Shooter

Xueqing Zou

...

2020/2/14

See List of Professors in Ching Chiek Koh, Gene University(University of Cambridge)

Co-Authors

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