Ching Chiek Koh, Gene
University of Cambridge
H-index: 18
Europe-United Kingdom
Top articles of Ching Chiek Koh, Gene
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Genetic interaction library screening with a next-generation dual guide CRISPR system | bioRxiv | Thomas Burgold Emre Karakoc Emanuel Goncalves Lisa Dwane Inigo Barrio-Hernandez | 2024 |
The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells | Nature Genetics | Gene Ching Chiek Koh Soraya Boushaki Salome Jingchen Zhao Andrew Marcel Pregnall Firas Sadiyah | 2024/1 |
A rare genetic disorder provides insights into mechanisms of early-onset neurodegeneration | medRxiv | Cherif Badja Sophie Momen Gene Ching Cheik Koh Soraya Boushaki Theodoros I Roumeliotis | 2023 |
Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells | Nature Genetics | Foad J Rouhani Xueqing Zou Petr Danecek Cherif Badja Tauanne Dias Amarante | 2022/9 |
All driven by energy demand? Integrative comparison of metabolism of Enterococcus faecalis wildtype and a glutamine synthase mutant | Microbiology Spectrum | Seyed Babak Loghmani Eric Zitzow Gene Ching Chiek Koh Andreas Ulmer Nadine Veith | 2022/4/27 |
Substitution mutational signatures in whole-genome–sequenced cancers in the UK population | Science | Andrea Degasperi Xueqing Zou Tauanne Dias Amarante Andrea Martinez-Martinez Gene Ching Chiek Koh | 2022/4/22 |
FANCD2-associated nuclease 1 partially compensates for the lack of exonuclease 1 in mismatch repair | Molecular and Cellular Biology | Katja Kratz Mariela Artola-Borán Saho Kobayashi-Era Gene Koh Goncalo Oliveira | 2021/9/1 |
Mutational signatures: emerging concepts, caveats and clinical applications | Gene Koh Andrea Degasperi Xueqing Zou Sophie Momen Serena Nik-Zainal | 2021/10 | |
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage | Nature cancer | Xueqing Zou Gene Ching Chiek Koh Arjun Scott Nanda Andrea Degasperi Katie Urgo | 2021/6 |
Dissecting mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage | BiorXiv | Xueqing Zou Gene Ching Chiek Koh Arjun Scott Nanda Andrea Degasperi Katie Urgo | 2020/8/6 |
Mutational signatures: experimental design and analytical framework | Gene Koh Xueqing Zou Serena Nik-Zainal | 2020/12 | |
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts | Nature communications | Ilias Georgakopoulos-Soares Gene Koh Sophie E Momen Josef Jiricny Martin Hemberg | 2020/4/24 |
Direct mutational consequences of CRISPR-cas9 gene-edited DNA repair genes | Cancer Research | Xueqing Zou Gene Koh Scott Nanda Andrea Degasperi Katie Urgo | 2020/8/15 |
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies | Nature cancer | Andrea Degasperi Tauanne Dias Amarante Jan Czarnecki Scott Shooter Xueqing Zou | 2020/2/14 |