Cheryl Arrowsmith
University of Toronto
H-index: 110
North America-Canada
Top articles of Cheryl Arrowsmith
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
A public-private partnership that supports the discovery of new medicines through open access research. | Target | SGC UNC | 2037 |
PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites | bioRxiv | MONA ALQAZZAZ Felipe Eduardo Ciamponi Sr Jolene Caifeng Ho Maxim I Maron Manisha Yadav | 2024 |
Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design | Nature Chemical Biology | Matthieu Schapira Levon Halabelian Cheryl H Arrowsmith Rachel J Harding | 2024/3/8 |
Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex | bioRxiv | Matthew ER Maitland Gabriel Onea Dominic DG Owens Brianna C Gonga-Cavé Xu Wang | 2024 |
Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations | Experimental Hematology | Mona A Alqazzaz Genna M Luciani Victoria Vu Raquel AC Machado Magdalena M Szewczyk | 2024/2/1 |
A resource to enable chemical biology and drug discovery of WDR Proteins | bioRxiv | Cheryl H Arrowsmith Suzanne Ackloo Fengling Li Magda Szewczyk Almagul Seitova | 2024 |
ChemRAP uncovers specific mRNA translation regulation via RNA 5′ phospho-methylation | EMBO reports | Hélène Ipas Ellen B Gouws Nathan S Abell Po-Chin Chiou Sravan K Devanathan | 2024/1/23 |
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor | Journal of medicinal chemistry | Yan Xiong Holger Greschik Catrine Johansson Ludwig Seifert Vicki Gamble | 2024/3/27 |
Huntingtin is an RNA-binding protein and participates in NEAT1-mediated paraspeckles | bioRxiv | Manisha Yadav Rachel J Harding Tiantian Li Xin Xu Terence Gall-Duncan | 2024 |
PRMT1 is a critical dependency in clear cell renal cell carcinoma with roles in post-transcriptional regulation and DNA damage response | bioRxiv | Joseph Walton Angel SN Ng Karen Arevalo Anthony Apostoli Jalna Meens | 2023 |
Therapeutic Discovery for Chromatin Complexes: Where Do We Stand? | Dominic DG Owens Matthew ER Maitland Cheryl H Arrowsmith Dalia Barsyte-Lovejoy | 2024/1/11 | |
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex | RSC Medicinal Chemistry | Aliakbar Khalili Yazdi Sumera Perveen Cheng Dong Xiaosheng Song Aiping Dong | 2024 |
Structure-guided drug discovery: back to the future | Nature Structural & Molecular Biology | Cheryl H Arrowsmith | 2024/3/14 |
RAS and PP2A activities converge on phosphoregulation of epigenetic complexes in cancer | Cancer Research | Mukund Sharma Anna Aakula Francesco Tabaro Henrik Honkanen Jesse Kamila | 2023/4/4 |
Detection of antibodies against the huntingtin protein in human plasma | Cellular and Molecular Life Sciences | Hélèna L Denis Melanie Alpaugh Claudia P Alvarez Alexis Fenyi Roger A Barker | 2023/2 |
Discovery of a novel DCAF1 ligand using a drug–target interaction prediction model: generalizing machine learning to new drug targets | Journal of Chemical Information and Modeling | Serah W Kimani Julie Owen Stuart R Green Fengling Li Yanjun Li | 2023/6/23 |
Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40 | Structure | Matthew G Alteen Justin C Deme Claudia P Alvarez Peter Loppnau Ashley Hutchinson | 2023/9/7 |
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition | Communications Biology | Serah W Kimani Sumera Perveen Magdalena Szewezyk Hong Zeng Aiping Dong | 2023/12/16 |
Targeting epigenetic regulation in clear cell renal cell carcinoma reveals PRMT1 as a novel target | Joseph Walton | 2023 | |
PBRM1, SETD2 and BAP1—the trinity of 3p in clear cell renal cell carcinoma | Joseph Walton Keith Lawson Panagiotis Prinos Antonio Finelli Cheryl Arrowsmith | 2023/2 |
