Chang-Ching Lin

About Chang-Ching Lin

Chang-Ching Lin, With an exceptional h-index of 13 and a recent h-index of 10 (since 2020), a distinguished researcher at University of Texas Southwestern Medical Center, specializes in the field of Cancer research.

His recent articles reflect a diverse array of research interests and contributions to the field:

Abstract PS17-09: An FGFR1/2 degrader overcomes antiestrogen resistance in ER+/FGFR1-amplified breast cancer

Abstract PO1-23-09: A bedside-to-bench translational analysis demonstrates that NF1 alterations promote CDK4/6 inhibitor (CDK4/6i) resistance in hormone receptor-positive (HR+ …

Abstract PO3-23-09: ESR1 mutations drive resistance to CDK4/6 inhibitors in ER+ Breast Cancer

Abstract PS03-04: Tumor immune microenvironment modulates resistance to estrogen suppression in ER+ breast cancer

Combined inhibition of CDK4/6 and AKT is highly active against the luminal androgen receptor (LAR) subtype of triple negative breast cancer (TNBC)

PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

PRMT5 is an actionable target in CDK4/6 inhibitor-resistant ER+/Rb-deficient breast cancer

Chang-Ching Lin Information

University

Position

___

Citations(all)

428

Citations(since 2020)

321

Cited By

200

hIndex(all)

13

hIndex(since 2020)

10

i10Index(all)

14

i10Index(since 2020)

10

Email

University Profile Page

Google Scholar

Chang-Ching Lin Skills & Research Interests

Cancer research

Top articles of Chang-Ching Lin

Abstract PS17-09: An FGFR1/2 degrader overcomes antiestrogen resistance in ER+/FGFR1-amplified breast cancer

Cancer Research

2024/5/2

Abstract PO1-23-09: A bedside-to-bench translational analysis demonstrates that NF1 alterations promote CDK4/6 inhibitor (CDK4/6i) resistance in hormone receptor-positive (HR+ …

Cancer Research

2024/5/2

Abstract PO3-23-09: ESR1 mutations drive resistance to CDK4/6 inhibitors in ER+ Breast Cancer

Cancer Research

2024/5/2

Abstract PS03-04: Tumor immune microenvironment modulates resistance to estrogen suppression in ER+ breast cancer

Cancer Research

2024/5/2

Combined inhibition of CDK4/6 and AKT is highly active against the luminal androgen receptor (LAR) subtype of triple negative breast cancer (TNBC)

Cancer Research

2023/4/4

PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

Nature communications

2024/3/13

Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

Research Square

2023/7/10

PRMT5 is an actionable target in CDK4/6 inhibitor-resistant ER+/Rb-deficient breast cancer

Cancer Research

2023/4/4

Immune cells infiltration and activation are higher in breast cancers resistant to antiestrogen therapy

Cancer Research

2023/4/4

Abstract P5-02-02: Genomic Landscape of ER+/HER2-metastatic breast cancer as a function of prior treatment with a CDK4/6 inhibitor

Cancer Research

2023/3/1

Chang-Ching Lin
Chang-Ching Lin

H-Index: 7

Ariella Hanker
Ariella Hanker

H-Index: 13

Epigenetic repression of STING by MYC promotes immune evasion and resistance to immune checkpoint inhibitors in triple-negative breast cancer

Cancer immunology research

2022/7/1

Abstract GS3-09: Loss of ASXL1 tumor suppressor promotes resistance to CDK4/6 inhibitors in ER+ breast cancer

Cancer Research

2022/2/15

Abstract P5-17-09: A genome-wide CRISPR screen identifies PRMT5 as a novel therapeutic target in ER+/RB1-deficient breast cancer

Cancer Research

2022/2/15

Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

Cancer cell

2021/8/9

Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer

Clinical Cancer Research

2021/8/1

Abstract GS1-06: FGFR1 associates with gene promoters and regulates gene transcription: Implications for endocrine resistance in ER+/FGFR1-amplified breast cancer

Cancer Research

2021/2/15

Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer

Nature communications

2020/10/30

Combined p53-and PTEN-deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer

Journal of Biological Chemistry

2020/8/21

Corrigendum to “Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer”[Canc. Lett. 438 (2018, Dec 1) 165–173](Cancer Letters (2018) 438 (165–173 …

Cancer Letters

2020/6/28

Abstract GS6-04: Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, breast cancer progression, and HER2 inhibitor sensitivity

Cancer Research

2020/2/15

Dan Ye
Dan Ye

H-Index: 6

Chang-Ching Lin
Chang-Ching Lin

H-Index: 7

Jie He
Jie He

H-Index: 12

See List of Professors in Chang-Ching Lin University(University of Texas Southwestern Medical Center)