Celia A Schiffer

Celia A Schiffer

University of Massachusetts Medical School

H-index: 65

North America-United States

About Celia A Schiffer

Celia A Schiffer, With an exceptional h-index of 65 and a recent h-index of 38 (since 2020), a distinguished researcher at University of Massachusetts Medical School,

His recent articles reflect a diverse array of research interests and contributions to the field:

Contributions of Hyperactive Mutations in Mpro from SARS-CoV-2 to Drug Resistance

Direct delivery of stabilized Cas-embedded base editors achieves efficient and accurate editing of clinically relevant targets

Structure-based Antiviral Design against HTLV-1 Protease

Crystal Structures of Inhibitor-Bound Main Protease from Delta-and Gamma-Coronaviruses

Antiviral Compounds

Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors

Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance

FruitFire: a luciferase based on a fruit fly metabolic enzyme

Celia A Schiffer Information

University

Position

Professor of Biochemistry and Molecular Pharmacology, University of Massachusetts

Citations(all)

12242

Citations(since 2020)

4733

Cited By

9162

hIndex(all)

65

hIndex(since 2020)

38

i10Index(all)

186

i10Index(since 2020)

136

Email

University Profile Page

University of Massachusetts Medical School

Google Scholar

View Google Scholar Profile

Top articles of Celia A Schiffer

Title

Journal

Author(s)

Publication Date

Contributions of Hyperactive Mutations in Mpro from SARS-CoV-2 to Drug Resistance

ACS Infectious Diseases

Julia M Flynn

Sarah N Zvornicanin

Tenzin Tsepal

Ala M Shaqra

Nese Kurt Yilmaz

...

2024/3/12

Direct delivery of stabilized Cas-embedded base editors achieves efficient and accurate editing of clinically relevant targets

bioRxiv

Jeong Min Lee

Jing Zeng

Pengpeng Liu

My Anh Nguyen

Diego Suchenski Loustaunau

...

2024

Structure-based Antiviral Design against HTLV-1 Protease

Journal of Biological Chemistry

Sarah Zvornicanin

Celia Schiffer

Nese KurtYilmaz

Ala Shaqra

Akbar Ali

...

2023/1/1

Crystal Structures of Inhibitor-Bound Main Protease from Delta-and Gamma-Coronaviruses

Viruses

Sarah N Zvornicanin

Ala M Shaqra

Qiuyu J Huang

Elizabeth Ornelas

Mallika Moghe

...

2023/3/18

Antiviral Compounds

2022/11/10

Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors

BioRxiv

COVID Moonshot Consortium

Hagit Achdout

Anthony Aimon

Dominic S Alonzi

Robert Arbon

...

2020/10/30

Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance

Elife

Ean Spielvogel

Sook-Kyung Lee

Shuntai Zhou

Gordon J Lockbaum

Mina Henes

...

2023/3/15

FruitFire: a luciferase based on a fruit fly metabolic enzyme

bioRxiv

Spencer T Adams Jr

Jacqueto Zephyr

Markus F Bohn

Celia A Schiffer

Stephen C Miller

2023/6/30

Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease

Bioorganic chemistry

Jacqueto Zephyr

Desaboini Nageswara Rao

Colby Johnson

Ala M Shaqra

Ellen A Nalivaika

...

2023/2/1

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

Science

Melissa L Boby

Daren Fearon

Matteo Ferla

Mihajlo Filep

Lizbé Koekemoer

...

2023/11/10

Systematic analyses of the resistance potential of drugs targeting SARS-CoV-2 main protease

ACS infectious diseases

Julia M Flynn

Qiu Yu J Huang

Sarah N Zvornicanin

Gila Schneider-Nachum

Ala M Shaqra

...

2023/6/30

Characterizing influenza virus entry using cryo-electron tomography and convolutional neural networks

Journal of Biological Chemistry

Qiu Yu Huang

Kangkang Song

James Munro

Celia Schiffer

Mohan Somasundaran

2023/1/1

Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans

Immunity

Nicholas D Peterson

Y Tse Samantha

Qiuyu Judy Huang

Khursheed A Wani

Celia A Schiffer

...

2023/4/11

Addressing the dNTP bottleneck restricting prime editing activity

bioRxiv

Karthikeyan Ponnienselvan

Pengpeng Liu

Thomas Nyalile

Sarah Oikemus

Anya T Joynt

...

2023/10/21

Pre-emptively Avoiding Drug Resistance: Lessons from viral proteases

Journal of Biological Chemistry

Celia Schiffer

2023

Hepatitis c virus ns3/4a protease inhibitors

2022/7/21

HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues

European Journal of Medicinal Chemistry

Gordon J Lockbaum

Linah N Rusere

Mina Henes

Klajdi Kosovrasti

Desaboini Nageswara Rao

...

2023/9/5

Quantitative structural analysis of influenza virus by cryo-electron tomography and convolutional neural networks

Structure

Qiuyu J Huang

Kangkang Song

Chen Xu

Daniel NA Bolon

Jennifer P Wang

...

2022/5/5

Bacterial pattern recognition in C. elegans by a nuclear hormone receptor

bioRxiv

Nicholas D Peterson

Samantha Y Tse

Qiuyu Judy Huang

Celia A Schiffer

Read Pukkila-Worley

2022/7/13

Identification of a Permissive Secondary Mutation That Restores the Enzymatic Activity of Oseltamivir Resistance Mutation H275Y

Journal of virology

Li Jiang

Neha Samant

Ping Liu

Mohan Somasundaran

Jeffrey D Jensen

...

2022/3/23

See List of Professors in Celia A Schiffer University(University of Massachusetts Medical School)

Co-Authors

H-index: 137
Katherine Fitzgerald

Katherine Fitzgerald

University of Massachusetts Medical School

H-index: 104
Robert M. Stroud

Robert M. Stroud

University of California, San Francisco

H-index: 92
Robert Shafer

Robert Shafer

Stanford University

H-index: 85
Michael K Gilson

Michael K Gilson

University of California, San Diego

H-index: 62
Piet Gros

Piet Gros

Universiteit Utrecht

H-index: 54
Jeffrey D. Jensen

Jeffrey D. Jensen

Arizona State University

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