Caroline A. (Lewis) Chidley

Caroline A. (Lewis) Chidley

Massachusetts Institute of Technology

H-index: 39

North America-United States

About Caroline A. (Lewis) Chidley

Caroline A. (Lewis) Chidley, With an exceptional h-index of 39 and a recent h-index of 37 (since 2020), a distinguished researcher at Massachusetts Institute of Technology, specializes in the field of Metabolite Profiling.

His recent articles reflect a diverse array of research interests and contributions to the field:

Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization

Nucleotide imbalance decouples cell growth from cell proliferation

Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine

Caroline A. (Lewis) Chidley Information

University

Position

Whitehead Institute

Citations(all)

8599

Citations(since 2020)

7391

Cited By

3495

hIndex(all)

39

hIndex(since 2020)

37

i10Index(all)

50

i10Index(since 2020)

48

Email

University Profile Page

Massachusetts Institute of Technology

Google Scholar

View Google Scholar Profile

Caroline A. (Lewis) Chidley Skills & Research Interests

Metabolite Profiling

Top articles of Caroline A. (Lewis) Chidley

Title

Journal

Author(s)

Publication Date

Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells

Nature Metabolism

Samantha J Linder

Tiziano Bernasocchi

Bárbara Martínez-Pastor

Kelly D Sullivan

Matthew D Galbraith

...

2023/12

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

Cell chemical biology

Keene L Abbott

Ahmed Ali

Dominick Casalena

Brian T Do

Raphael Ferreira

...

2023/9/21

S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

Elife

Adwait A Godbole

Sneha Gopalan

Thien-Kim Nguyen

Alexander L Munden

Dominique S Lui

...

2023/2/9

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

bioRxiv

Keene L Abbott

Ahmed Ali

Bradley I Reinfeld

Amy Deik

Sonu Subudhi

...

2023/12/24

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Blood, The Journal of the American Society of Hematology

Anne C Wilke

Carmen Doebele

Alena Zindel

Kwang Seok Lee

Sara A Rieke

...

2022/1/27

Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization

Cell reports

Michael R MacArthur

Sarah J Mitchell

Katia S Chadaideh

J Humberto Treviño-Villarreal

Jonathan Jung

...

2022/8/16

Nucleotide imbalance decouples cell growth from cell proliferation

Nature cell biology

Frances F Diehl

Teemu P Miettinen

Ryan Elbashir

Christopher S Nabel

Alicia M Darnell

...

2022/8

Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine

Science

Andrew L Cangelosi

Anna M Puszynska

Justin M Roberts

Andrea Armani

Thao P Nguyen

...

2022/7/1

Author Correction: Histidine catabolism is a major determinant of methotrexate sensitivity

Nature

Naama Kanarek

Heather R Keys

Jason R Cantor

Caroline A Lewis

Sze Ham Chan

...

2022/2/3

CLN3 is required for the clearance of glycerophosphodiesters from lysosomes

Nature

Nouf N Laqtom

Wentao Dong

Uche N Medoh

Andrew L Cangelosi

Vimisha Dharamdasani

...

2022/9/29

Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy

Leukemia

Yana Pikman

Nicole Ocasio-Martinez

Gabriela Alexe

Boris Dimitrov

Samuel Kitara

...

2022/2

Cancer tissue of origin constrains the growth and metabolism of metastases

bioRxiv

Sharanya Sivanand

Yetis Gultekin

Peter S Winter

Sidney Y Vermeulen

Konstantine Tchourine

...

2022/8/18

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia

Science translational medicine

Grzegorz Sienski

Priyanka Narayan

Julia Maeve Bonner

Nora Kory

Sebastian Boland

...

2021/3/3

Fumarate is a terminal electron acceptor in the mammalian electron transport chain

Science

Jessica B Spinelli

Paul C Rosen

Hans-Georg Sprenger

Anna M Puszynska

Jessica L Mann

...

2021/12/3

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

Molecular cell

Alba Luengo

Zhaoqi Li

Dan Y Gui

Lucas B Sullivan

Maria Zagorulya

...

2021/2/18

Methionine synthase is essential for cancer cell proliferation in physiological folate environments

Nature metabolism

Mark R Sullivan

Alicia M Darnell

Montana F Reilly

Tenzin Kunchok

Lena Joesch-Cohen

...

2021/11

A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma

Nature metabolism

Jee-Eun Choi

Carlos Sebastian

Christina M Ferrer

Caroline A Lewis

Moshe Sade-Feldman

...

2021/2

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

Cell Reports

Miyeko D Mana

Amanda M Hussey

Constantine N Tzouanas

Shinya Imada

Yesenia Barrera Millan

...

2021/6/8

Identifying Cell‐Type‐Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Current protocols

Nadja Gebert

Shahadat Rahman

Caroline A Lewis

Alessandro Ori

Chia‐Wei Cheng

2021/9

Cell-programmed nutrient partitioning in the tumour microenvironment

Nature

Bradley I Reinfeld

Matthew Z Madden

Melissa M Wolf

Anna Chytil

Jackie E Bader

...

2021/5/13

See List of Professors in Caroline A. (Lewis) Chidley University(Massachusetts Institute of Technology)