Bruno Guigas

Bruno Guigas

Universiteit Leiden

H-index: 49

Europe-Netherlands

About Bruno Guigas

Bruno Guigas, With an exceptional h-index of 49 and a recent h-index of 34 (since 2020), a distinguished researcher at Universiteit Leiden, specializes in the field of Type 2 diabetes, Immunometabolism, Helminths, AMPK, Metformin.

His recent articles reflect a diverse array of research interests and contributions to the field:

A 30‐color spectral flow cytometry panel for comprehensive analysis of immune cell composition and macrophage subsets in mouse metabolic organs

A polyphenol-rich plant extract prevents hypercholesterolemia and modulates gut microbiota in western diet-fed mice

Combined glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonism attenuates atherosclerosis severity in APOE* 3-Leiden. CETP mice

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation

Metabolic sensor AMPK licenses CD103+ dendritic cells to induce Treg responses

Metformin: Update on mechanisms of action and repurposing potential

Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗ 3-Leiden. CETP mice

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

Bruno Guigas Information

University

Position

Leiden University Medical Center

Citations(all)

12273

Citations(since 2020)

5677

Cited By

8861

hIndex(all)

49

hIndex(since 2020)

34

i10Index(all)

86

i10Index(since 2020)

73

Email

University Profile Page

Universiteit Leiden

Google Scholar

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Bruno Guigas Skills & Research Interests

Type 2 diabetes

Immunometabolism

Helminths

AMPK

Metformin

Top articles of Bruno Guigas

Title

Journal

Author(s)

Publication Date

A 30‐color spectral flow cytometry panel for comprehensive analysis of immune cell composition and macrophage subsets in mouse metabolic organs

Cytometry Part A

Joost M Lambooij

Tamar Tak

Arnaud Zaldumbide

Bruno Guigas

2024/4/23

A polyphenol-rich plant extract prevents hypercholesterolemia and modulates gut microbiota in western diet-fed mice

Frontiers in Cardiovascular Medicine

Cédric Langhi

Marie Vallier

Auriane Bron

Yolanda F Otero

Maheva Maura

...

2024

Combined glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonism attenuates atherosclerosis severity in APOE* 3-Leiden. CETP mice

Atherosclerosis

Robin van Eenige

Zhixiong Ying

Naomi Tramper

Vera Wiebing

Zohor Siraj

...

2023/5/1

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation

EMBO Molecular Medicine

Enchen Zhou

Xiaoke Ge

Hiroyuki Nakashima

Rumei Li

Hendrik JP van der Zande

...

2023/8/7

Metabolic sensor AMPK licenses CD103+ dendritic cells to induce Treg responses

bioRxiv

Thiago A Patente

Eline C Brombacher

Graham A Heieis

Leonard R Pelgrom

Anna Zawistowska-Deniziak

...

2023/2/21

Metformin: Update on mechanisms of action and repurposing potential

Marc Foretz

Bruno Guigas

Benoit Viollet

2023/8

Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗ 3-Leiden. CETP mice

eBioMedicine

Zhixiong Ying

Robin van Eenige

Xiaoke Ge

Christy van Marwijk

Joost M Lambooij

...

2023/7/1

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

Elife

Cong Liu

Milena Schönke

Borah Spoorenberg

Joost M Lambooij

Hendrik JP van der Zande

...

2023/1/17

Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption

Nutrients

Cédric Langhi

Marie Vallier

Yolanda F Otero

Maheva Maura

Florian Le Joubioux

...

2023/12/9

Schistosoma mansoni egg-derived thioredoxin and Sm14 drive the development of IL-10 producing regulatory B cells

PLoS neglected tropical diseases

Mathilde AM Chayé

Thomas A Gasan

Arifa Ozir-Fazalalikhan

Maaike R Scheenstra

Anna Zawistowska-Deniziak

...

2023/6/26

AMPK activation induces RALDHhigh tolerogenic dendritic cells through rewiring of glucose and lipid metabolism

bioRxiv

Eline C Brombacher

Thiago A Patente

Alwin J van der Ham

Tijmen JA Moll

Frank Otto

...

2023

Early but Not Late Exercise Training in Mice Exacerbates Hepatic Inflammation in Developing Nonalcoholic Fatty Liver Disease

Journal of Clinical and Translational Hepatology

Artemiy Kovynev

Zhixiong Ying

Joost M Lambooij

Hendrik JP van der Zande

Bruno Guigas

...

2023/10/10

Dendritic cell–intrinsic LKB1-AMPK/SIK signaling controls metabolic homeostasis by limiting the hepatic Th17 response during obesity

JCI insight

JP Hendrik

Eline C Brombacher

Joost M Lambooij

Leonard R Pelgrom

Anna Zawistowska-Deniziak

...

2023/6/6

A novel polyphenol-rich combination of 5 plant extracts prevents high-fat diet-induced body weight gain by regulating intestinal macronutrient absorption in mice

Nutrition Research

Vivien Chavanelle

Cédric Langhi

Arnaud Michaux

Doriane Ripoche

Yolanda F Otero

...

2023/10/1

ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis

Frontiers in Endocrinology

Saurabh Vig

Joost M Lambooij

Mette C Dekkers

Frank Otto

Françoise Carlotti

...

2022/9/12

Immune Regulation of Metabolic Homeostasis

Frontiers in Endocrinology

Bruno Guigas

Tony Jourdan

Rinke Stienstra

2022/5/31

Fasciola hepatica Fatty Acid Binding Protein 1 Modulates T cell Polarization by Promoting Dendritic Cell Thrombospondin-1 Secretion Without Affecting Metabolic …

Frontiers in Immunology

Anna Zawistowska-Deniziak

Joost M Lambooij

Alicja Kalinowska

Thiago A Patente

Maciej Łapiński

...

2022/5/26

Direct AMPK activation corrects NASH in rodents through metabolic effects and direct action on inflammation and fibrogenesis

Hepatology Communications

Pascale Gluais‐Dagorn

Marc Foretz

Gregory R Steinberg

Battsetseg Batchuluun

Anna Zawistowska‐Deniziak

...

2022/1

TOTUM‐63, a plant‐based polyphenol‐rich extract, improves glycaemic control in subjects with prediabetes or early stage newly‐diagnosed type 2 diabetes in a randomized, double …

Diabetes, Obesity and Metabolism

Pascal Sirvent

Vivien Chavanelle

Yolanda F Otero

Maxime Bargetto

Florian Le Joubioux

...

2022/12

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes

Frontiers in immunology

Sanne GS Verberk

Hendrik JP van der Zande

Jeroen Baardman

Kyra E de Goede

Karl J Harber

...

2021/4/26

See List of Professors in Bruno Guigas University(Universiteit Leiden)

Co-Authors

H-index: 130
Michael Pollak

Michael Pollak

McGill University

H-index: 78
Ko Willems van Dijk

Ko Willems van Dijk

Universiteit Leiden

H-index: 76
Patrick Rensen

Patrick Rensen

Universiteit Leiden

H-index: 58
Bertrand Luc

Bertrand Luc

Université Catholique de Louvain

H-index: 51
Hermelijn H. Smits

Hermelijn H. Smits

Universiteit Leiden

H-index: 51
Christophe Beauloye

Christophe Beauloye

Université Catholique de Louvain

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