Brian O'Rourke

Brian O'Rourke

Johns Hopkins University

H-index: 94

North America-United States

About Brian O'Rourke

Brian O'Rourke, With an exceptional h-index of 94 and a recent h-index of 47 (since 2020), a distinguished researcher at Johns Hopkins University, specializes in the field of mitochondria, calcium, failure, arrhythmia, ROS.

His recent articles reflect a diverse array of research interests and contributions to the field:

Regulation of stress granules by O-GlcNAcylation in stressed and ischemic cardiomyocytes

Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19

Formaldehyde dehydrogenase-derived formate contributes to cardioprotection in the female heart

Oxidative stress in the mitochondrial matrix underlies ischemia/reperfusion-induced mitochondrial instability

Abstract P2189: Role Of Innate Immune Response And Mitochondrial Ros In The Cardiac And Pulmonary Sequelae Of Covid-19

Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity

Fractal dynamics of individual mitochondrial oscillators measure local inter-mitochondrial coupling

Abstract P3195: Mitochondrial CaMKII Drives Cardiometabolic Dysfunction In Heart Failure

Brian O'Rourke Information

University

Position

___

Citations(all)

30606

Citations(since 2020)

7418

Cited By

25808

hIndex(all)

94

hIndex(since 2020)

47

i10Index(all)

221

i10Index(since 2020)

166

Email

University Profile Page

Johns Hopkins University

Google Scholar

View Google Scholar Profile

Brian O'Rourke Skills & Research Interests

mitochondria

calcium

failure

arrhythmia

ROS

Top articles of Brian O'Rourke

Title

Journal

Author(s)

Publication Date

Regulation of stress granules by O-GlcNAcylation in stressed and ischemic cardiomyocytes

Biophysical Journal

Hannah C Swimm

Wenxi Zhang

Yashas Mallikarjun

Deepthi Ashok

D Brian Foster

...

2024/2/8

Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19

bioRxiv

Deepthi Ashok

Ting Liu

Joseph Criscione

Meghana Prakash

Byunggik Kim

...

2024/1/8

Formaldehyde dehydrogenase-derived formate contributes to cardioprotection in the female heart

Haley Garbus

Raihan Kabir

Obialunanma Ebenebe

Brian O'Rourke

Mark Kohr

2023/5/23

Oxidative stress in the mitochondrial matrix underlies ischemia/reperfusion-induced mitochondrial instability

Journal of Biological Chemistry

Soroosh Solhjoo

Ting Liu

Agnieszka Sidor

Dong I Lee

Brian O’Rourke

...

2023/1/1

Abstract P2189: Role Of Innate Immune Response And Mitochondrial Ros In The Cardiac And Pulmonary Sequelae Of Covid-19

Circulation Research

Ting Liu

Deepthi Ashok

Morgan Craney

Amanda Wong

DB Foster

...

2023/8/4

Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity

Cell Chemical Biology

Alexia Pearah

Balamurugan Ramatchandirin

Ting Liu

Risa M Wolf

Arisa Ikeda

...

2023/12/21

Fractal dynamics of individual mitochondrial oscillators measure local inter-mitochondrial coupling

Biophysical journal

Felix T Kurz

Miguel A Aon

Heinz-Peter Schlemmer

Johann ME Jende

Brian O’Rourke

...

2023/4/18

Abstract P3195: Mitochondrial CaMKII Drives Cardiometabolic Dysfunction In Heart Failure

Circulation Research

Kimberly Ferrero

Robert Cole

DB Foster

Jonathan Granger

Brian O'Rourke

...

2023/8/4

Sex Differences in the Phosphorylation of Argonaute 2 Result in Reduced Translocation of Micro RNA-181c Into the Mitochondria and Cardioprotection in Pre-Menopausal Females

Circulation

Diego T Quiroga

Barbara Roman

Haley Garbus

Obialunanma Ebenebe

Brian O'Rourke

...

2023/11/7

Inhibiting O-GlcNAcylation impacts p38 and Erk1/2 signaling and perturbs cardiomyocyte hypertrophy

Journal of Biological Chemistry

Kyriakos N Papanicolaou

Jessica Jung

Deepthi Ashok

Wenxi Zhang

Amir Modaressanavi

...

2023/3/1

Distinct Effects of Mitochondrial Na+/Ca2+ Exchanger Inhibition and Ca2+ Uniporter Activation on Ca2+ Sparks and Arrhythmogenesis in Diabetic Rats

Journal of the American Heart Association

Sathya Velmurugan

Ting Liu

Kuey C Chen

Florin Despa

Brian O'Rourke

...

2023/7/18

Decoding Angiotensin Receptors: TOMAHAQ‐Based Detection and Quantification of Angiotensin Type‐1 and Type‐2 Receptors

Journal of the American Heart Association

Caglar Cosarderelioglu

Simion Kreimer

Alma I Plaza‐Rodriguez

Pablo A Iglesias

C Conover Talbot Jr

...

2023/9/19

Growth Differentiation Factor‐15 Predicts Mortality and Heart Failure Exacerbation But Not Ventricular Arrhythmias in Patients With Cardiomyopathy

Journal of the American Heart Association

M Scott Binder

Lisa R Yanek

Wanjun Yang

Barbara Butcher

Sanaz Norgard

...

2023/2/7

Fidgetin-like 2 as a target to enhance skin graft healing

2023/6/29

Kir1. 1 and SUR1 are not implicated as subunits of an adenosine triphosphate-sensitive potassium channel involved in diazoxide cardioprotection

JTCVS open

Jie Wang

Kyriakos Papanicolaou

Robert Tryon

Janelle Sangalang

Ben Salazar

...

2023/9/1

Myocardial brain-derived neurotrophic factor regulates cardiac bioenergetics through the transcription factor Yin Yang 1

Cardiovascular research

Xue Yang

Manling Zhang

Bingxian Xie

Zishan Peng

Janet R Manning

...

2023/2/1

Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca2+ uptake

Journal of Biological Chemistry

Deepthi Ashok

Kyriakos Papanicolaou

Agnieszka Sidor

Michelle Wang

Soroosh Solhjoo

...

2023/6/1

Abstract P1166: O-GlcNAcylation Regulates Protein Synthesis In Cardiomyocytes Through Effects On The Translational Regulator Eif2α

Circulation Research

Kyriakos Papanicolaou

Jessica Jung

Wenxi Zhang

Deepthi Ashok

D Brian Foster

...

2023/8/4

Molecular and cellular mechanisms by which cardiac sympathetic denervation prevents heart failure and sudden cardiac arrest

bioRxiv

Deeptankar DeMazumder

Pooja Joshi

Brian O’Rourke

Shanea Estes

Swati Dey

2023/1/31

Mitochondrial creatine kinase attenuates pathologic remodeling in heart failure

Circulation research

Gizem Keceli

Ashish Gupta

Joevin Sourdon

Refaat Gabr

Michael Schär

...

2022/3/4

See List of Professors in Brian O'Rourke University(Johns Hopkins University)