Brian M. Baker

Brian M. Baker

University of Notre Dame

H-index: 48

North America-United States

About Brian M. Baker

Brian M. Baker, With an exceptional h-index of 48 and a recent h-index of 32 (since 2020), a distinguished researcher at University of Notre Dame, specializes in the field of structural biology, T cells, molecular biophysics, immunology, signaling.

His recent articles reflect a diverse array of research interests and contributions to the field:

Quantification and prediction of T-cell cross-reactivity through experimental and computational methods

Accurate modeling of peptide-MHC structures with AlphaFold

Distinct sets of molecular characteristics define tumor-rejecting neoantigens

The impact of SARS-CoV-2 Spike mutation on peptide presentation is HLA allomorph-specific

Enhanced T cell receptor specificity through framework engineering

T cell receptor therapeutics: immunological targeting of the intracellular cancer proteome

CD8+ T Cell–Dependent Antitumor Activity In Vivo of a Mass Spectrometry–Identified Neoepitope despite Undetectable CD8+ Immunogenicity In Vitro

The energetic landscape of catch bonds in TCR interfaces

Brian M. Baker Information

University

Position

Department of Chemistry & Biochemistry

Citations(all)

6759

Citations(since 2020)

2684

Cited By

5112

hIndex(all)

48

hIndex(since 2020)

32

i10Index(all)

91

i10Index(since 2020)

71

Email

University Profile Page

University of Notre Dame

Google Scholar

View Google Scholar Profile

Brian M. Baker Skills & Research Interests

structural biology

T cells

molecular biophysics

immunology

signaling

Top articles of Brian M. Baker

Title

Journal

Author(s)

Publication Date

Quantification and prediction of T-cell cross-reactivity through experimental and computational methods

Frontiers in Immunology

Dinler A Antunes

Brian M Baker

Markus Cornberg

Liisa K Selin

2024/2/20

Accurate modeling of peptide-MHC structures with AlphaFold

Structure

Victor Mikhaylov

Chad A Brambley

Grant LJ Keller

Alyssa G Arbuiso

Laura I Weiss

...

2024/2/1

Distinct sets of molecular characteristics define tumor-rejecting neoantigens

bioRxiv

Anngela C Adams

Anne M Macy

Elizabeth S Borden

Lauren M Herrmann

Chad A Brambley

...

2024

The impact of SARS-CoV-2 Spike mutation on peptide presentation is HLA allomorph-specific

Current Research in Structural Biology

You Min Ahn

Janesha C Maddumage

Emma J Grant

Demetra SM Chatzileontiadou

WWJ Gihan Perera

...

2024/4/29

Enhanced T cell receptor specificity through framework engineering

Frontiers in Immunology

Aaron M Rosenberg

Cory M Ayres

Angélica V Medina-Cucurella

Timothy A Whitehead

Brian M Baker

2024/3/12

T cell receptor therapeutics: immunological targeting of the intracellular cancer proteome

Christopher A Klebanoff

Smita S Chandran

Brian M Baker

Sergio A Quezada

Antoni Ribas

2023/12

CD8+ T Cell–Dependent Antitumor Activity In Vivo of a Mass Spectrometry–Identified Neoepitope despite Undetectable CD8+ Immunogenicity In Vitro

The Journal of Immunology

Marc A Gillig

Cory A Brennick

Mariam M George

Jeremy L Balsbaugh

Tatiana V Shcheglova

...

2023/11/15

The energetic landscape of catch bonds in TCR interfaces

Cory M Ayres

Steve A Corcelli

Brian M Baker

2023/8/1

Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality

The Journal of clinical investigation

Tiffany Shi

Ashley R Burg

J Timothy Caldwell

Krishna M Roskin

Cyd M Castro-Rojas

...

2023/7/17

Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes

Proceedings of the National Academy of Sciences

Jean M Custodio

Cory M Ayres

Tatiana J Rosales

Chad A Brambley

Alyssa G Arbuiso

...

2023/12/19

CD8 T Cell− Dependent Antitumor Activity In Vivo of a Mass Spectrometry− Identified Neoepitope despite Undetectable CD8 Immunogenicity In Vitro

Marc A Gillig

Cory A Brennick

Mariam M George

Jeremy L Balsbaugh

Tatiana V Shcheglova

...

2023

Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts

Frontiers in Immunology

M Eyad Khorki

Tiffany Shi

Eileen E Cianciolo

Ashley R Burg

P Chukwunalu Chukwuma

...

2023/12/8

Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA

Nature medicine

Smita S Chandran

Jiaqi Ma

Martin G Klatt

Friederike Dündar

Chaitanya Bandlamudi

...

2022/5

Identification of immunologically protective neo-epitopes for the treatment of cancers

2022/8/11

Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes

Frontiers in Immunology

Grant LJ Keller

Laura I Weiss

Brian M Baker

2022/4/25

Chaperoning the dance of antigen presentation

Nature Chemical Biology

Tatiana J Rosales

Brian M Baker

2022/8

A previously unappreciated polymorphism in the beta chain of I-As expressed in autoimmunity-prone SJL mice: Combined impact on antibody, CD4 T cell recognition and MHC class II …

Molecular immunology

Katherine A Richards

Courtney Lavery

Grant LJ Keller

Jim Miller

Brian M Baker

...

2022/3/1

Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma

Scientific Reports

Chang Liu

Hong Liu

Moumita Dasgupta

Lance M Hellman

Xiaogang Zhang

...

2022/7/15

Predicting immunogenic peptides using structural and physical modeling

2022/2/17

Peptide-dependent tuning of major histocompatibility complex motional properties and the consequences for cellular immunity

Cory M Ayres

Brian M Baker

2022/6/1

See List of Professors in Brian M. Baker University(University of Notre Dame)

Co-Authors

H-index: 112
K. Christopher Garcia

K. Christopher Garcia

Stanford University

H-index: 111
George Coukos

George Coukos

Université de Lausanne

H-index: 86
Pramod K Srivastava PhD MD

Pramod K Srivastava PhD MD

University of Connecticut

H-index: 46
Brian G. Pierce

Brian G. Pierce

University of Maryland

H-index: 46
P* Rizkallah

P* Rizkallah

Cardiff University

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