Brian Kobilka
Stanford University
H-index: 144
North America-United States
Top articles of Brian Kobilka
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Time-resolved cryo-EM of G-protein activation by a GPCR | bioRxiv | Makaía M Papasergi-Scott Guillermo Perez-Hernnadez Hossein Batebi Yang Gao Gozde Eskici | 2023 |
Stepwise activation of a metabotropic glutamate receptor | Nature | Kaavya Krishna Kumar Haoqing Wang Chris Habrian Naomi R Latorraca Jun Xu | 2024/4/17 |
Negative allosteric modulation of the µ-opioid receptor | Biophysical Journal | Evan S O'Brien Vipin A Rangari Amal El Daibani Shainnel O Eans Betsy White | 2024/2/8 |
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor | Nature | Jiawei Zhao Matthias Elgeti Evan S O’Brien Cecília P Sár Amal EI Daibani | 2024/4/10 |
Structure and dynamics determine G protein coupling specificity at a class A GPCR | bioRxiv | Marina Casiraghi Haoqing Wang Patrick Brennan Chris Habrian Harald Hübner | 2024/3/29 |
Molecular insights into G protein specificity and biased agonism at the β 2-adrenergic receptor | bioRxiv | Marina Casiraghi Haoqing Wang Patrick Brennan Chris Habrian Harald Hübner | 2024/3/29 |
Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof | 2022/3/31 | ||
Allosteric modulators of cannabinoid receptors and methods of treating neuropathic pain | 2023/2/16 | ||
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics | Nature communications | Xinyu Xu Jeremy Shonberg Jonas Kaindl Mary J Clark Anne Stößel | 2023/4/14 |
Structural basis of α1A-adrenergic receptor activation and recognition by an extracellular nanobody | Nature Communications | Yosuke Toyoda Angqi Zhu Fang Kong Sisi Shan Jiawei Zhao | 2023/6/20 |
Arrestin C-tail dynamics regulate activation and GPCR engagement | Biophysical Journal | John Janetzko Asuka Inoue Yuqi Shi Jonathan C Deutsch Korak Kumar Ray | 2023/2/10 |
Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor | Nature communications | Jie Heng Yunfei Hu Guillermo Pérez-Hernández Asuka Inoue Jiawei Zhao | 2023/4/10 |
Mechanistic insights into G protein association with a G protein-coupled receptor | Hossein Batebi Guillermo Pérez-Hernández Jesper Mathiesen Mingyu Shi Johanna KS Tiemann | 2023/6/13 | |
Structure-based design of bitopic ligands for the µ-opioid receptor | Nature | Abdelfattah Faouzi Haoqing Wang Saheem A Zaidi Jeffrey F DiBerto Tao Che | 2023/1/26 |
Insights into distinct signaling profiles of the µOR activated by diverse agonists | Nature chemical biology | Qianhui Qu Weijiao Huang Deniz Aydin Joseph M Paggi Alpay B Seven | 2023/4 |
Structure based approaches on fentanyl template to design novel mu opioid modulators | Rohini Ople Haoqing Wang Qiongyu Li Ben Polacco Sarah Bernhard | 2023/6/1 | |
Molecular determinants of ligand efficacy and potency in GPCR signaling | Science | Franziska M Heydenreich Maria Marti-Solano Manbir Sandhu Brian K Kobilka Michel Bouvier | 2023/12/22 |
Negative allosteric modulation of the glucagon receptor by RAMP2 | Cell | Kaavya Krishna Kumar Evan S O’Brien Chris H Habrian Naomi R Latorraca Haoqing Wang | 2023/3/30 |
Methods for quantifying ligand efficacy in G-protein coupled receptors using single-molecule fluorescence energy transfer | 2023/12/5 | ||
Structural basis for activation of CB1 by an endocannabinoid analog | Nature Communications | Kaavya Krishna Kumar Michael J Robertson Elina Thadhani Haoqing Wang Carl-Mikael Suomivuori | 2023/5/9 |
