Bernhard E. Flucher

Bernhard E. Flucher

Medizinische Universität Innsbruck

H-index: 47

Europe-Austria

About Bernhard E. Flucher

Bernhard E. Flucher, With an exceptional h-index of 47 and a recent h-index of 24 (since 2020), a distinguished researcher at Medizinische Universität Innsbruck, specializes in the field of Voltage-gated calcium channels, skeletal muscle EC-coupling, synaptogenesis.

His recent articles reflect a diverse array of research interests and contributions to the field:

Role of the charge transfer center as a bimodal regulator of voltage-dependence and kinetics of CaV voltage sensor action

Characterizing the role of voltage-sensing domains of CaV3. 3 determining gating properties

The extracellular S3-S4 loop of CaV1. 1 voltage-sensors as specific modulator of EC coupling and calcium currents

Asymmetric contribution of a selectivity filter gate in triggering inactivation of CaV1. 3 channels

Identifying the CaV1. 1 voltage-sensing domains involved in channel gating and excitation contraction coupling

Ionic interactions between gating charges and countercharges in voltage-sensing domain I independently regulate kinetics and voltage-dependence of Cav1. 1 gating

Voltage-dependent transitions between resting and activated states of the four Cav1. 1 voltage sensors observed in MD simulation

CaV3.3 Channelopathies

Bernhard E. Flucher Information

University

Position

Department of Physiology & Medical Physics

Citations(all)

5897

Citations(since 2020)

1642

Cited By

4784

hIndex(all)

47

hIndex(since 2020)

24

i10Index(all)

88

i10Index(since 2020)

62

Email

University Profile Page

Medizinische Universität Innsbruck

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Bernhard E. Flucher Skills & Research Interests

Voltage-gated calcium channels

skeletal muscle EC-coupling

synaptogenesis

Top articles of Bernhard E. Flucher

Title

Journal

Author(s)

Publication Date

Role of the charge transfer center as a bimodal regulator of voltage-dependence and kinetics of CaV voltage sensor action

Biophysical Journal

Martin C Heiss

Monica L Fernandez-Quintero

Simone Pelizzari

Yousra El Ghaleb

Marta Campiglio

...

2024/2/8

Characterizing the role of voltage-sensing domains of CaV3. 3 determining gating properties

Biophysical Journal

Anna-Lena M Fischer

Martin C Heiss

Yousra El Ghaleb

Johannes R Löffler

Klaus R Liedl

...

2024/2/8

The extracellular S3-S4 loop of CaV1. 1 voltage-sensors as specific modulator of EC coupling and calcium currents

Biophysical Journal

Simone Pelizzari

Monica L Fernandez-Quintero

Marta Campiglio

Martin C Heiss

Yousra El Ghaleb

...

2024/2/8

Asymmetric contribution of a selectivity filter gate in triggering inactivation of CaV1. 3 channels

Journal of General Physiology

Pedro J del Rivero Morfin

Audrey L Kochiss

Klaus R Liedl

Bernhard E Flucher

Monica LI Fernández-Quintero

...

2024/2/5

Identifying the CaV1. 1 voltage-sensing domains involved in channel gating and excitation contraction coupling

Biophysical Journal

Simone Pelizzari

Monica L Fernandez-Quintero

Marta Campiglio

Petronel Tuluc

Yousra El Ghaleb

...

2023/2/10

Ionic interactions between gating charges and countercharges in voltage-sensing domain I independently regulate kinetics and voltage-dependence of Cav1. 1 gating

Biophysical Journal

Martin C Heiss

Monica L Fernandez-Quintero

Simone Pelizzari

Yousra El Ghaleb

Marta Campiglio

...

2023/2/10

Voltage-dependent transitions between resting and activated states of the four Cav1. 1 voltage sensors observed in MD simulation

Biophysical Journal

Monica L Fernández-Quintero

Simone Pelizzari

Yousra El Ghaleb

Martin C Heiss

Klaus R Liedl

...

2023/2/10

CaV3.3 Channelopathies

Yousra El Ghaleb

Bernhard E Flucher

2023/1/3

Two newly identified CACNA1I variants linked to neurodevelopmental disorder and epilepsy differentially affect Cav3. 3 gating properties

Biophysical Journal

Yousra El Ghaleb

Monica L Fernandez-Quintero

Marta Campiglio

Klaus R Liedl

Astrid S Plomp

...

2023/2/10

Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1. 1

Biophysical Journal

Yousra El Ghaleb

Nadine J Ortner

Wilfried Posch

Monica L Fernández-Quintero

Wietske E Tuinte

...

2022/2/11

STAC3 determines the slow activation kinetics of CaV1.1 currents and inhibits its voltage‐dependent inactivation

Journal of Cellular Physiology

Wietske E Tuinte

Enikő Török

Irene Mahlknecht

Petronel Tuluc

Bernhard E Flucher

...

2022/11

Counteractive and cooperative actions of muscle β-catenin and CaV1. 1 during early neuromuscular synapse formation

Iscience

Mehmet Mahsum Kaplan

Bernhard E Flucher

2022/4/15

STAC proteins inhibit calcium and voltage dependent inactivation of L-type calcium channels

Biophysical Journal

Wietske E Tuinte

Petronel Tuluc

Bernhard E Flucher

Marta Campiglio

2022/2/11

Defining the roles of VSD II & III of Cav1. 1 in regulating calcium currents and EC-coupling

Biophysical Journal

Simone Pelizzari

Yousra El Ghaleb

Martin C Heiss

Monica L Fernández-Quintero

Petronel Tuluc

...

2022/2/11

Molecular mechanisms of disease-causing mutations in the first voltage-sensing domain of Cav1. 1

Biophysical Journal

Martin C Heiss

Monica L Fernandez-Quintero

Yousra El Ghaleb

Simone Pelizzari

Petronel Tuluc

...

2022/2/11

The Skeletal Muscle Calcium Channel

Bernhard E Flucher

Kurt G Beam

2022/11/8

Ion-pair interactions between voltage-sensing domain IV and pore domain I regulate CaV1. 1 gating

Biophysical Journal

Yousra El Ghaleb

Monica L Fernández-Quintero

Stefania Monteleone

Petronel Tuluc

Marta Campiglio

...

2021/10/19

CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders

Brain

Yousra El Ghaleb

Pauline E Schneeberger

Monica L Fernández-Quintero

Stefanie M Geisler

Simone Pelizzari

...

2021/7/1

Structural determinants of voltage-gating properties in calcium channels

Elife

Monica L Fernández-Quintero

Yousra El Ghaleb

Petronel Tuluc

Marta Campiglio

Klaus R Liedl

...

2021/3/30

Multiple sequence variants in STAC3 affect interactions with CaV1. 1 and excitation-contraction coupling

Structure

Britany Rufenach

Darren Christy

Bernhard E Flucher

Jennifer M Bui

Jörg Gsponer

...

2020/8/4

See List of Professors in Bernhard E. Flucher University(Medizinische Universität Innsbruck)