Ben Kleinstiver
Harvard University
H-index: 30
North America-United States
Top articles of Ben Kleinstiver
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Splice modulators target PMS1 to reduce somatic expansion of the Huntington’s disease-associated CAG repeat | Nature Communications | Zachariah L McLean Dadi Gao Kevin Correia Jennie CL Roy Shota Shibata | 2024/4/12 |
CRISPR-Cas Genome Editing in Ex Vivo Human Lungs | The Journal of Heart and Lung Transplantation | K Mesaki H Yamamoto S Juvet J Yeung Z Guan | 2024/4/1 |
Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy | Nature Biomedical Engineering | Christiano RR Alves Leillani L Ha Rebecca Yaworski Emma R Sutton Cicera R Lazzarotto | 2024/2 |
In situ architecture of Opa1-dependent mitochondrial cristae remodeling | The EMBO Journal | Michelle Y Fry Paula P Navarro Pusparanee Hakim Virly Y Ananda Xingping Qin | 2024/2/1 |
CRISPR-Cas9-AAV versus lentivector transduction for genome modification of X-linked severe combined immunodeficiency hematopoietic stem cells | Frontiers in Immunology | Julie Brault Taylor Liu Siyuan Liu Amanda Lawson Uimook Choi | 2023/1/4 |
A Preclinical Study of CRISPR Porcine Cell Gene Editing Combined with IL-10 Gene Delivery for Donor Lung Immunomodulation | The Journal of Heart and Lung Transplantation | N Yoshiyasu K Mesaki Z Guan S Juvet B Kleinstiver | 2023/4/1 |
Sniper2L is a high-fidelity Cas9 variant with high activity | Nature chemical biology | Young-hoon Kim Nahye Kim Ikenna Okafor Sungchul Choi Seonwoo Min | 2023/8 |
PAM-flexible genome editing with an engineered chimeric Cas9 | Nature Communications | Lin Zhao Sabrina RT Koseki Rachel A Silverstein Nadia Amrani Christina Peng | 2023/10/4 |
Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease | bioRxiv | Doo Eun Choi Jun Wan Shin Sophia Zeng Eun Pyo Hong Jae-Hyun Jang | 2023 |
SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia | Brain | Siddharth Srivastava Hagar Mor Shaked Kenneth Gable Sita D Gupta Xueyang Pan | 2023/4/3 |
PMS1 as a target for splice modulation to prevent somatic CAG repeat expansion in Huntington’s disease | bioRxiv | Zachariah L McLean Dadi Gao Kevin Correia Jennie CL Roy Shota Shibata | 2023/7/27 |
Immunomodulation of the donor lung with CRISPR-mediated activation of IL-10 expression | The Journal of Heart and Lung Transplantation | Kumi Mesaki Stephen Juvet Jonathan Yeung Zehong Guan Gavin W Wilson | 2023/10/1 |
Evolution of CRISPR-associated endonucleases as inferred from resurrected proteins | Nature Microbiology | Borja Alonso-Lerma Ylenia Jabalera Sara Samperio Matias Morin Almudena Fernandez | 2023/1 |
Multimodal CRISPR perturbations of GWAS loci associated with coronary artery disease in vascular endothelial cells | PLoS genetics | Florian Wünnemann Thierry Fotsing Tadjo Mélissa Beaudoin Simon Lalonde Ken Sin Lo | 2023/3/16 |
Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis | Immunity | Máté G Kiss John E Mindur Abi G Yates Donghoon Lee John F Fullard | 2023/7/11 |
Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases | bioRxiv | Joana Ferreira da Silva Connor J Tou Emily M King Madeline L Eller Linyuan Ma | 2023/9/13 |
Precise DNA cleavage using CRISPR-SpRYgests | Nature biotechnology | Kathleen A Christie Jimmy A Guo Rachel A Silverstein Roman M Doll Megumu Mabuchi | 2023/3 |
Precise cut-and-paste DNA insertion using engineered type VK CRISPR-associated transposases | Nature Biotechnology | Connor J Tou Benno Orr Benjamin P Kleinstiver | 2023/7 |
Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo | Nature Communications | Yong Tao Veronica Lamas Wan Du Wenliang Zhu Yiran Li | 2023/8/15 |
Base editing as a genetic treatment for spinal muscular atrophy | bioRxiv | Christiano RR Alves Leillani L Ha Rebecca Yaworski Cicera R Lazzarotto Kathleen A Christie | 2023/1/21 |
Co-Authors
