Bart van de Sluis, PhD

Bart van de Sluis, PhD

Rijksuniversiteit Groningen

H-index: 47

Europe-Netherlands

About Bart van de Sluis, PhD

Bart van de Sluis, PhD, With an exceptional h-index of 47 and a recent h-index of 33 (since 2020), a distinguished researcher at Rijksuniversiteit Groningen, specializes in the field of Cholesterol metabolism, endosomal trafficking, inflammation, liver disease, gene-editing/CRISPR-Cas9 transgenic mouse technology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice

VLDL Biogenesis and Secretion: it takes a village

Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway

The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR …

The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes

Cargo-specific role for retriever subunit VPS26C in hepatocyte lipoprotein receptor recycling to control postprandial triglyceride-rich lipoproteins

Mitochondrial DNA methylation in metabolic associated fatty liver disease

Prevention of atherosclerosis and hepatic steatosis by combined, liver-specific deletion of GPR146 and ANGPTL3

Bart van de Sluis, PhD Information

University

Position

Tenure Track Professor of Molecular Genetics (Department of Pediatrics)

Citations(all)

14857

Citations(since 2020)

9323

Cited By

8952

hIndex(all)

47

hIndex(since 2020)

33

i10Index(all)

85

i10Index(since 2020)

75

Email

University Profile Page

Rijksuniversiteit Groningen

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Bart van de Sluis, PhD Skills & Research Interests

Cholesterol metabolism

endosomal trafficking

inflammation

liver disease

gene-editing/CRISPR-Cas9 transgenic mouse technology

Top articles of Bart van de Sluis, PhD

Title

Journal

Author(s)

Publication Date

Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice

Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

Andries Heida

Theo van Dijk

Marieke Smit

Martijn Koehorst

Mirjam Koster

...

2024/3/1

VLDL Biogenesis and Secretion: it takes a village

Willemien van Zwol

Bart van de Sluis

Henry N Ginsberg

Jan Albert Kuivenhoven

2024/1/19

Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway

Pharmacological research

Zhixiong Ying

Robin van Eenige

Rosa Beerepoot

Mariëtte R Boon

Niels J Kloosterhuis

...

2023/1/1

The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR …

Toxicology and Applied Pharmacology

Andrea C Postmus

Janine K Kruit

Roos E Eilers

Rick Havinga

Mirjam H Koster

...

2023/6/1

The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes

bioRxiv

Dyonne Y Vos

Markus G Barbosa

Andries H Heida

W Alfredo Rios-Ocampo

Joel J Tissink

...

2023/8/9

Cargo-specific role for retriever subunit VPS26C in hepatocyte lipoprotein receptor recycling to control postprandial triglyceride-rich lipoproteins

Arteriosclerosis, thrombosis, and vascular biology

Dyonne Y Vos

Melinde Wijers

Marieke Smit

Nicolette Huijkman

Niels J Kloosterhuis

...

2023/1

Mitochondrial DNA methylation in metabolic associated fatty liver disease

Frontiers in nutrition

Archibold Mposhi

Fabian Cortés-Mancera

Janette Heegsma

Vincent E De Meijer

Bart Van de Sluis

...

2023/5/25

Prevention of atherosclerosis and hepatic steatosis by combined, liver-specific deletion of GPR146 and ANGPTL3

Atherosclerosis

U Tharehalli Mathada

A Rimbert

B Zhang

N Kloosterhuis

N Huijkman

...

2023/8/1

Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia

Cancer & metabolism

Martijn GS Rutten

Yu Lei

Joanne H Hoogerland

Vincent W Bloks

Hong Yang

...

2023/4/21

GPR146 and HDL metabolism

Atherosclerosis

B Zhang

U Tharehalli Mathada

N Loaiza

L Martinez

N Huijkman

...

2023/8/1

Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet

International Journal of Molecular Sciences

Sebastiaan Lambooy

Andries Heida

Christian Joschko

Dalibor Nakladal

Azuwerus van Buiten

...

2023/4/10

Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain

Life science alliance

Esther Stroo

Leen Janssen

Olga Sin

Wytse Hogewerf

Mirjam Koster

...

2023/7/1

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology

Audrey Deprince

Nathalie Hennuyer

Sander Kooijman

Amanda CM Pronk

Eric Baugé

...

2023/4/1

Characterization of a novel bile salt export pump deficiency mouse model with the p. E297g mutation

Antonia Felzen

Milaine Hovingh

Rick Havinga

Niels Mulder

Martijn Koehorst

...

2023/6

Prevention of Triglyceridemia by (Non-) Anticoagulant Heparin (oids) Does Not Preclude Transplant Vasculopathy and Glomerulosclerosis

Frontiers in Cell and Developmental Biology

Pragyi Shrestha

Kirankumar Katta

Ditmer Talsma

Annamaria Naggi

Jan-Luuk Hillebrands

...

2022/3/7

The endosomal sorting protein VPS35 controls lipid homeostasis through regulating hepatic lysosomal function

Atherosclerosis

DY Vos

A Heida

M Koster

J Tissink

KB Kuentzel

...

2022/8/1

Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

Scientific reports

Maaike Blankestijn

Vincent W Bloks

Dicky Struik

Nicolette Huijkman

Niels Kloosterhuis

...

2022/2/15

Hepatic SMLR1 ablation fully protects against diet-induced atherosclerosis but causes hepatosteatosis via reduced VLDL secretion

Atherosclerosis

W Van Zwol

A Rimbert

JC Wolters

V Bloks

NJ Kloosterhuis

...

2022/8/1

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.

Hepatology (Baltimore, Md.)

Willemien van Zwol

Antoine Rimbert

Justina C Wolters

Marieke Smit

Vincent W Bloks

...

2022/10/12

Posttranscriptional regulation of the human LDL receptor by the U2-spliceosome

Circulation research

Paolo Zanoni

Grigorios Panteloglou

Alaa Othman

Joel T Haas

Roger Meier

...

2022/1/7

See List of Professors in Bart van de Sluis, PhD University(Rijksuniversiteit Groningen)

Co-Authors

H-index: 169
Cisca Wijmenga, PhD

Cisca Wijmenga, PhD

Rijksuniversiteit Groningen

H-index: 95
Marten Hofker

Marten Hofker

Rijksuniversiteit Groningen

H-index: 80
Derek Mann

Derek Mann

Newcastle University

H-index: 80
Peter Pearson

Peter Pearson

Universidade de São Paulo

H-index: 72
Jan Albert Kuivenhoven

Jan Albert Kuivenhoven

Rijksuniversiteit Groningen

H-index: 54
Harm van Bakel

Harm van Bakel

Icahn School of Medicine at Mount Sinai

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