Anup Ramachandran

Anup Ramachandran

University of Kansas

H-index: 56

North America-United States

About Anup Ramachandran

Anup Ramachandran, With an exceptional h-index of 56 and a recent h-index of 43 (since 2020), a distinguished researcher at University of Kansas,

His recent articles reflect a diverse array of research interests and contributions to the field:

Acetaminophen hepatotoxicity: Paradigm for understanding mechanisms of drug-induced liver injury

The p21+ perinecrotic hepatocytes produce the chemokine CXCL14 after a severe acetaminophen overdose promoting hepatocyte injury and delaying regeneration

The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice

Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure

Comments on: Unveiling the therapeutic promise of natural products in alleviating drug-induced liver injury: Present advancements and future prospects.

Spatial analysis of renal acetaminophen metabolism and its modulation by 4-methylpyrazole with DESI mass spectrometry imaging

Central mechanisms of acetaminophen hepatotoxicity: Mitochondrial dysfunction by protein adducts and oxidant stress

Cxcl14 as predictive biomarker for acute liver failure and death

Anup Ramachandran Information

University

Position

University of Kansas Medical Center

Citations(all)

14364

Citations(since 2020)

7484

Cited By

9509

hIndex(all)

56

hIndex(since 2020)

43

i10Index(all)

110

i10Index(since 2020)

86

Email

University Profile Page

Google Scholar

Top articles of Anup Ramachandran

Title

Journal

Author(s)

Publication Date

Acetaminophen hepatotoxicity: Paradigm for understanding mechanisms of drug-induced liver injury

Hartmut Jaeschke

Anup Ramachandran

2024/1/24

The p21+ perinecrotic hepatocytes produce the chemokine CXCL14 after a severe acetaminophen overdose promoting hepatocyte injury and delaying regeneration

Toxicology

David S Umbaugh

Nga T Nguyen

Sawyer H Smith

Anup Ramachandran

Hartmut Jaeschke

2024/4/12

The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice

Archives of Toxicology

Olamide B Adelusi

Jephte Y Akakpo

Gary Eichenbaum

Ejaz Sadaff

Anup Ramachandran

...

2024/3/29

Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure

Anup Ramachandran

Jephte Y Akakpo

Steven C Curry

Barry H Rumack

Hartmut Jaeschke

2024/2/10

Comments on: Unveiling the therapeutic promise of natural products in alleviating drug-induced liver injury: Present advancements and future prospects.

Phytotherapy Research: PTR

Hartmut Jaeschke

Anup Ramachandran

2024/2/5

Spatial analysis of renal acetaminophen metabolism and its modulation by 4-methylpyrazole with DESI mass spectrometry imaging

Toxicological Sciences

Jephte Yao Akakpo

Hernando Olivos

Bindesh Shrestha

Anthony Midey

Hartmut Jaeschke

...

2024/1/30

Central mechanisms of acetaminophen hepatotoxicity: Mitochondrial dysfunction by protein adducts and oxidant stress

Hartmut Jaeschke

Anup Ramachandran

2023/1/1

Cxcl14 as predictive biomarker for acute liver failure and death

2023/9/21

Hepatocyte Senescence is Initiated through a Klf6-p21 Mechanism which mediates the Production of Cxcl14, a Novel Prognostic Biomarker of Acute Liver Failure

David Umbaugh

Nga Nguyen

Giselle Sanchez Guerrero

Cecilia Villanueva

Bruno Hagenbuch

...

2023/6/1

Translocation of Adenosine A2B Receptor to Mitochondria Influences Cytochrome P450 2E1 Activity after Acetaminophen Overdose

Livers

Giselle Sanchez-Guerrero

David S Umbaugh

Abhay A Ramachandran

Antonio Artigues

Hartmut Jaeschke

...

2023/12/26

Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice

Archives of Toxicology

Nga T Nguyen

David S Umbaugh

Sawyer Smith

Olamide B Adelusi

Giselle Sanchez-Guerrero

...

2023/5

Lack of mitochondrial Cyp2E1 drives acetaminophen-induced ER stress-mediated apoptosis in mouse and human kidneys: Inhibition by 4-methylpyrazole but not N-acetylcysteine

Toxicology

Jephte Y Akakpo

Anup Ramachandran

Barry H Rumack

Darren P Wallace

Hartmut Jaeschke

2023/12/1

Mitochondria in acetaminophen-induced liver injury and recovery: a concise review

Anup Ramachandran

Hartmut Jaeschke

2023/4/10

Nrf2 as a therapeutic target in acetaminophen hepatotoxicity: A case study with sulforaphane

Journal of Biochemical and Molecular Toxicology

Yasaman Etemadi

Jephte Y Akakpo

Anup Ramachandran

Hartmut Jaeschke

2023/12

Putative Effects of an Orally Administered Anti-TLR4 Antibody on Gut Microbiota and Acetaminophen Hepatotoxicity in Mice

Microbiology Spectrum

Hartmut Jaeschke

Anup Ramachandran

2023/2/14

The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure

Hepatology

David S Umbaugh

Nga T Nguyen

Steven C Curry

Jody A Rule

William M Lee

...

2023/11/1

The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice

Toxicology and applied pharmacology

Olamide B Adelusi

Anup Ramachandran

John J Lemasters

Hartmut Jaeschke

2022/6/15

Activation of the adenosine A2B receptor even beyond the therapeutic window of N-acetylcysteine accelerates liver recovery after an acetaminophen overdose

Food and Chemical Toxicology

Luqi Duan

Giselle Sanchez-Guerrero

Hartmut Jaeschke

Anup Ramachandran

2022/5/1

Role of pyroptosis in acetaminophen-induced hepatotoxicity

Hartmut Jaeschke

David S Umbaugh

Anup Ramachandran

2022/12/13

Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose

Jephte Y Akakpo

Anup Ramachandran

Steven C Curry

Barry H Rumack

Hartmut Jaeschke

2022/2

See List of Professors in Anup Ramachandran University(University of Kansas)