Aneel Aggarwal
Icahn School of Medicine at Mount Sinai
H-index: 67
North America-United States
Top articles of Aneel Aggarwal
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides | Nature Structural & Molecular Biology | Olga Rechkoblit Daniela Sciaky Dale F Kreitler Angeliki Buku Jithesh Kottur | 2024/2/6 |
Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation | bioRxiv | Richard Quintana-Feliciano Jithesh Kottur Mi Ni Rikhi Ghosh Leslie Salas-Estrada | 2024 |
Signal-induced enhancer activation requires Ku70 to read topoisomerase1–DNA covalent complexes | Nature structural & molecular biology | Yuliang Tan Lu Yao Amir Gamliel Sreejith J Nair Havilah Taylor | 2023/2 |
Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer | Journal of Medicinal Chemistry | Xufen Yu Dongxu Li Jithesh Kottur Huen Suk Kim Laura E Herring | 2023/11/29 |
Nucleic acid mediated activation of a short prokaryotic Argonaute immune system | bioRxiv | Jithesh Kottur Radhika Malik Aneel K Aggarwal | 2023/9/17 |
Sox11 inhibitors for treating mantle cell lymphoma | 2023/8/3 | ||
Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals | PLoS Pathogens | Jithesh Kottur Kris M White M Luis Rodriguez Olga Rechkoblit Richard Quintana-Feliciano | 2023/7/31 |
Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro | BioRxiv | Duc-Duy Vu Alessio Bonucci Manon Brenière Metztli Cisneros-Aguirre Philippe Pelupessy | 2023/7/13 |
High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development | Nature structural & molecular biology | Jithesh Kottur Olga Rechkoblit Richard Quintana-Feliciano Daniela Sciaky Aneel K Aggarwal | 2022/9 |
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic | Oncogene | Dongxu Li Xufen Yu Jithesh Kottur Weida Gong Zhao Zhang | 2022/6/10 |
Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch | Nature communications | Radhika Malik Robert E Johnson Louise Prakash Satya Prakash Iban Ubarretxena-Belandia | 2022/2/25 |
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks | Developmental cell | Richa B Shah Jennifer L Kernan Anya van Hoogstraten Kiyohiro Ando Yuanyuan Li | 2021/8/9 |
Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease | Nature Communications | Katsutoshi Sato Amol A Padgaonkar Stacey J Baker Stephen C Cosenza Olga Rechkoblit | 2021/8/3 |
Shape of promoter antisense RNAs regulates ligand-induced transcription activation | Nature | Fan Yang Bogdan Tanasa Rudi Micheletti Kenneth A Ohgi Aneel K Aggarwal | 2021/7/15 |
Genome-wide detection and quantitation of RNA distribution by ChIRC13a-seq | Fan Yang Bogdan Tanasa Rudi Micheletti Kenneth A Ohgi Aneel K Aggarwal | 2021/7/1 | |
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models | Science translational medicine | Xufen Yu Dongxu Li Jithesh Kottur Yudao Shen Huen Suk Kim | 2021/9/29 |
Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase | Nature communications | Olga Rechkoblit Robert E Johnson Yogesh K Gupta Louise Prakash Satya Prakash | 2021/6/29 |
SOX11 inhibitors are cytotoxic in mantle cell lymphoma | Clinical Cancer Research | Shashidhar S Jatiani Stephanie Christie Violetta V Leshchenko Rinku Jain Abhijeet Kapoor | 2021/8/15 |
A contaminant impurity, not rigosertib, is a tubulin binding agent | Molecular cell | Stacey J Baker Stephen C Cosenza Saikrishna Athuluri-Divakar MV Ramana Reddy Rodrigo Vasquez-Del Carpio | 2020/7/2 |
Role of Nuclear Receptor Condensates in Ligand Induced Co‐operative Gene Regulation | The FASEB Journal | Sreejith J Nair Lu Yang Dario Meluzzi Feng Yang Soohwan Oh | 2020/4 |
