Andy Z.X. Zhu

Andy Z.X. Zhu

University of Toronto

H-index: 24

North America-Canada

About Andy Z.X. Zhu

Andy Z.X. Zhu, With an exceptional h-index of 24 and a recent h-index of 18 (since 2020), a distinguished researcher at University of Toronto, specializes in the field of Pharmacology, Drug Metabolism.

His recent articles reflect a diverse array of research interests and contributions to the field:

S305: Phase 2 randomized, placebo-controlled, double-blind, multicenter study of recombinant ADAMTS13 in patients with immune-mediated thrombotic thrombocytopenic purpura

Population Pharmacokinetics and Exposure-Response Analyses to Demonstrate the Link of Causality between ADAMTS13 and the Clinical Effects of Recombinant ADAMTS13 Compared to …

Quantitative System Pharmacology Modeling of the Effect of Recombinant ADAMTS13 on Platelets in Patients with Congenital Thrombotic Thrombocytopenic Purpura

Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen-targeting bispecific T cell engagers for treatment of …

Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion‐aided smoking cessation in African Americans? A …

Applications of Quantitative System Pharmacology Modeling to Model-Informed Drug Development

Functional characterization of novel rare CYP2A6 variants and potential implications for

Physiologically‐based pharmacokinetic modeling in renal and hepatic impairment populations: a pharmaceutical industry perspective

Andy Z.X. Zhu Information

University

Position

___

Citations(all)

1433

Citations(since 2020)

796

Cited By

976

hIndex(all)

24

hIndex(since 2020)

18

i10Index(all)

30

i10Index(since 2020)

27

Email

University Profile Page

Google Scholar

Andy Z.X. Zhu Skills & Research Interests

Pharmacology

Drug Metabolism

Top articles of Andy Z.X. Zhu

Title

Journal

Author(s)

Publication Date

S305: Phase 2 randomized, placebo-controlled, double-blind, multicenter study of recombinant ADAMTS13 in patients with immune-mediated thrombotic thrombocytopenic purpura

HemaSphere

Marie Scully

Jovanna Baptista

Indranil Bhattacharya

Spero Cataland

Paul Coppo

...

2023/8/1

Population Pharmacokinetics and Exposure-Response Analyses to Demonstrate the Link of Causality between ADAMTS13 and the Clinical Effects of Recombinant ADAMTS13 Compared to …

CPT: Pharmacometrics & Systems Pharmacology

Jennifer E Sager

Asma El‐Zailik

Julie Passarell

Stefan Roepcke

Xiaobin Li

...

2023/6

Quantitative System Pharmacology Modeling of the Effect of Recombinant ADAMTS13 on Platelets in Patients with Congenital Thrombotic Thrombocytopenic Purpura

Blood

Cameron McBride

Jiaolong Jiang

Zhiwei Zhang

John Tolsma

Björn Mellgård

...

2023/11/28

Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen-targeting bispecific T cell engagers for treatment of …

PLoS Computational Biology

Tomoki Yoneyama

Mi-Sook Kim

Konstantin Piatkov

Haiqing Wang

Andy ZX Zhu

2022/7/15

Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion‐aided smoking cessation in African Americans? A …

Addiction

Meghan J Chenoweth

Annie R Peng

Andy ZX Zhu

Lisa Sanderson Cox

Nikki L Nollen

...

2022/6/1

Applications of Quantitative System Pharmacology Modeling to Model-Informed Drug Development

Andy ZX Zhu

Mark Rogge

2022/4/19

Functional characterization of novel rare CYP2A6 variants and potential implications for

Clinical and translational science

Ahmed El‐Boraie

Julie‐Anne Tanner

Andy ZX Zhu

Katrina G Claw

Bhagwat Prasad

...

2022/1

Physiologically‐based pharmacokinetic modeling in renal and hepatic impairment populations: a pharmaceutical industry perspective

Clinical Pharmacology & Therapeutics

Tycho Heimbach

Yuan Chen

Jun Chen

Vaishali Dixit

Neil Parrott

...

2021/8

Quantitative systems pharmacology approaches for immuno‐oncology: adding virtual patients to the development paradigm

Vijayalakshmi Chelliah

Georgia Lazarou

Sumit Bhatnagar

John P Gibbs

Marjoleen Nijsen

...

2021/3

Evaluation of normothermic machine perfusion of porcine livers as a novel preclinical model to predict biliary clearance and transporter-mediated drug-drug interactions using …

Drug Metabolism and Disposition

Lianne J Stevens

Andy ZX Zhu

Paresh P Chothe

Swapan K Chowdhury

Joanne M Donkers

...

2021/9/1

The role of quantitative modeling and simulation in translational science

Venkatesh Pilla Reddy

Andy ZX Zhu

2020/1/1

Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody–Drug Conjugate in Patient-derived Xenografts

Molecular Cancer Therapeutics

Adnan O Abu-Yousif

Donna Cvet

Melissa Gallery

Bret M Bannerman

Michelle L Ganno

...

2020/10/1

A Translational Physiologically Based Pharmacokinetics/Pharmacodynamics Framework of Target-Mediated Disposition, Target Inhibition and Drug–Drug Interactions of Bortezomib

The AAPS Journal

Shinji Iwasaki

Andy Zhu

Michael Hanley

Karthik Venkatakrishnan

Cindy Xia

2020/5

A minimal physiologically‐based pharmacokinetic model demonstrates role of the neonatal Fc receptor (FcRn) competition in drug–disease interactions with antibody therapy

CPT: Pharmacometrics & Systems Pharmacology

Kotaro Itohara

Ikuko Yano

Tetsunori Tsuzuki

Miwa Uesugi

Shunsaku Nakagawa

...

2019/8

See List of Professors in Andy Z.X. Zhu University(University of Toronto)

Co-Authors

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