Andy Z.X. Zhu
University of Toronto
H-index: 24
North America-Canada
Top articles of Andy Z.X. Zhu
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
S305: Phase 2 randomized, placebo-controlled, double-blind, multicenter study of recombinant ADAMTS13 in patients with immune-mediated thrombotic thrombocytopenic purpura | HemaSphere | Marie Scully Jovanna Baptista Indranil Bhattacharya Spero Cataland Paul Coppo | 2023/8/1 |
Population Pharmacokinetics and Exposure-Response Analyses to Demonstrate the Link of Causality between ADAMTS13 and the Clinical Effects of Recombinant ADAMTS13 Compared to … | CPT: Pharmacometrics & Systems Pharmacology | Jennifer E Sager Asma El‐Zailik Julie Passarell Stefan Roepcke Xiaobin Li | 2023/6 |
Quantitative System Pharmacology Modeling of the Effect of Recombinant ADAMTS13 on Platelets in Patients with Congenital Thrombotic Thrombocytopenic Purpura | Blood | Cameron McBride Jiaolong Jiang Zhiwei Zhang John Tolsma Björn Mellgård | 2023/11/28 |
Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen-targeting bispecific T cell engagers for treatment of … | PLoS Computational Biology | Tomoki Yoneyama Mi-Sook Kim Konstantin Piatkov Haiqing Wang Andy ZX Zhu | 2022/7/15 |
Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion‐aided smoking cessation in African Americans? A … | Addiction | Meghan J Chenoweth Annie R Peng Andy ZX Zhu Lisa Sanderson Cox Nikki L Nollen | 2022/6/1 |
Applications of Quantitative System Pharmacology Modeling to Model-Informed Drug Development | Andy ZX Zhu Mark Rogge | 2022/4/19 | |
Functional characterization of novel rare CYP2A6 variants and potential implications for | Clinical and translational science | Ahmed El‐Boraie Julie‐Anne Tanner Andy ZX Zhu Katrina G Claw Bhagwat Prasad | 2022/1 |
Physiologically‐based pharmacokinetic modeling in renal and hepatic impairment populations: a pharmaceutical industry perspective | Clinical Pharmacology & Therapeutics | Tycho Heimbach Yuan Chen Jun Chen Vaishali Dixit Neil Parrott | 2021/8 |
Quantitative systems pharmacology approaches for immuno‐oncology: adding virtual patients to the development paradigm | Vijayalakshmi Chelliah Georgia Lazarou Sumit Bhatnagar John P Gibbs Marjoleen Nijsen | 2021/3 | |
Evaluation of normothermic machine perfusion of porcine livers as a novel preclinical model to predict biliary clearance and transporter-mediated drug-drug interactions using … | Drug Metabolism and Disposition | Lianne J Stevens Andy ZX Zhu Paresh P Chothe Swapan K Chowdhury Joanne M Donkers | 2021/9/1 |
The role of quantitative modeling and simulation in translational science | Venkatesh Pilla Reddy Andy ZX Zhu | 2020/1/1 | |
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody–Drug Conjugate in Patient-derived Xenografts | Molecular Cancer Therapeutics | Adnan O Abu-Yousif Donna Cvet Melissa Gallery Bret M Bannerman Michelle L Ganno | 2020/10/1 |
A Translational Physiologically Based Pharmacokinetics/Pharmacodynamics Framework of Target-Mediated Disposition, Target Inhibition and Drug–Drug Interactions of Bortezomib | The AAPS Journal | Shinji Iwasaki Andy Zhu Michael Hanley Karthik Venkatakrishnan Cindy Xia | 2020/5 |
A minimal physiologically‐based pharmacokinetic model demonstrates role of the neonatal Fc receptor (FcRn) competition in drug–disease interactions with antibody therapy | CPT: Pharmacometrics & Systems Pharmacology | Kotaro Itohara Ikuko Yano Tetsunori Tsuzuki Miwa Uesugi Shunsaku Nakagawa | 2019/8 |