Andrew L Lee

About Andrew L Lee

Andrew L Lee, With an exceptional h-index of 36 and a recent h-index of 17 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of proteins, dynamics, allostery, NMR.

His recent articles reflect a diverse array of research interests and contributions to the field:

Mixed, nonclassical behavior in a classic allosteric protein

Allosteric inactivation of an engineered optogenetic GTPase

Dynamic allostery in substrate binding by human thymidylate synthase

Visualizing an allosteric intermediate using cuaac stabilization of an NMR mixed labeled dimer

CuAAC stabilization of an NMR mixed labeled dimer

Backbone and ILVM methyl resonance assignments of human thymidylate synthase in apo and substrate bound forms

Mapping allosteric communications within individual proteins

Drugging Protein-Protein Interfaces of a Supramolecular Assembly as a Means to Overcome Resistance to Active Site Thymidylate Synthase Inhibitors

Andrew L Lee Information

University

Position

Professor of Chemical Biology and Medicinal Chemistry

Citations(all)

4481

Citations(since 2020)

963

Cited By

2171

hIndex(all)

36

hIndex(since 2020)

17

i10Index(all)

53

i10Index(since 2020)

31

Email

University Profile Page

Google Scholar

Andrew L Lee Skills & Research Interests

proteins

dynamics

allostery

NMR

Top articles of Andrew L Lee

Title

Journal

Author(s)

Publication Date

Mixed, nonclassical behavior in a classic allosteric protein

Proceedings of the National Academy of Sciences

Paul J Sapienza

Jeffrey P Bonin

HP Dinusha Jinasena

Kelin Li

Henry Dieckhaus

...

2023/9/19

Allosteric inactivation of an engineered optogenetic GTPase

Proceedings of the National Academy of Sciences

Abha Jain

Nikolay V Dokholyan

Andrew L Lee

2023/4/4

Dynamic allostery in substrate binding by human thymidylate synthase

Elife

Jeffrey P Bonin

Paul J Sapienza

Andrew L Lee

2022/10/6

Visualizing an allosteric intermediate using cuaac stabilization of an NMR mixed labeled dimer

ACS chemical biology

Paul J Sapienza

Michelle M Currie

Noah M Lancaster

Kelin Li

Jeffrey Aubé

...

2021/11/16

CuAAC stabilization of an NMR mixed labeled dimer

bioRxiv

Paul J Sapienza

Michelle M Currie

Kelin Li

Jeffrey Aubé

Andrew L Lee

2021/5/25

Backbone and ILVM methyl resonance assignments of human thymidylate synthase in apo and substrate bound forms

Biomolecular NMR assignments

Jeffrey P Bonin

Andrew L Lee

2021/4

Mapping allosteric communications within individual proteins

Nature communications

Jian Wang

Abha Jain

Leanna R McDonald

Craig Gambogi

Andrew L Lee

...

2020/7/31

Drugging Protein-Protein Interfaces of a Supramolecular Assembly as a Means to Overcome Resistance to Active Site Thymidylate Synthase Inhibitors

Biophysical Journal

Tigran M Abramyan

Alexander Tropsha

Andrew L Lee

Paul J Sapienza

2020/2/7

See List of Professors in Andrew L Lee University(University of North Carolina at Chapel Hill)