Andrew Fry
University of Leicester
H-index: 59
Europe-United Kingdom
Top articles of Andrew Fry
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
The mesenchymal morphology of cells expressing the EML4-ALK V3 oncogene is dependent on phosphorylation of Eg5 by NEK7 | Journal of Biological Chemistry | Sarah L Pashley Savvas Papageorgiou Laura O’Regan Giancarlo Barone Susan W Robinson | 2024/3/6 |
Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation | bioRxiv | Mohammad Zeeshan Ravish Rashpa David J Ferguson George Mckeown Raushan Nugmanova | 2024 |
BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms | Oncogene | Anita Singh Sara Busacca Aarti Gaba Michael Sheaff Charlotte Poile | 2023/2/17 |
Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells | bioRxiv | Naushin L Hindul Lauren R Abbott Sumaya MD Adan Kornelis R Straatman Andrew M Fry | 2023 |
Alternative treatment options to ALK inhibitor monotherapy for EML4-ALK-driven lung cancer | Savvas Papageorgiou Sarah L Pashley Laura O’Regan Sam Khan Richard Bayliss | 2022/7/15 | |
EML4-ALK variant 3 promotes mitotic errors and spindle assembly checkpoint deficiency leading to increased microtubule poison sensitivity | Molecular Cancer Research | Kellie Lucken Laura O'Regan Jene Choi Josephina Sampson Sarah L Pashley | 2022/6/3 |
Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes | Biology Open | Naushin L Hindul Amarjot Jhita Daiana G Oprea Tasnim Alamgir Hussain Oksana Gonchar | 2022/2/15 |
A polytherapy strategy using vincristine and ALK inhibitors to sensitise EML4-ALK-positive NSCLC | Cancers | Josephina Sampson Hyun-min Ju Ji-young Song Andrew M Fry Richard Bayliss | 2022/2/2 |
Cdk1-mediated threonine phosphorylation of Sam68 modulates its RNA binding, alternative splicing activity and cellular functions | Nucleic Acids Research | Idir Malki Inara Liepina Nora Kogelnik Hollie Watmuff Sue Robinson | 2022/12/9 |
BRCA1/MAD2L1 deficiency disrupts the spindle assembly checkpoint to confer vinorelbine resistance in mesothelioma | Molecular cancer therapeutics | Sara Busacca Laura O'Regan Anita Singh Annabel J Sharkey Alan G Dawson | 2021/2/1 |
Phase‐separated foci of EML4‐ALK facilitate signalling and depend upon an active kinase conformation | EMBO reports | Josephina Sampson Mark W Richards Jene Choi Andrew M Fry Richard Bayliss | 2021/12/6 |
EML4–ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7 | Journal of cell science | Laura O'Regan Giancarlo Barone Rozita Adib Chang Gok Woo Hui Jeong Jeong | 2020/5/1 |
Loss of BAP1/BRCA1 counteracts spindle assembly checkpoint activation by the anti-mesothelin antibody drug-conjugate anetumab ravtansine | Cancer Research | Anita Singh Jin-li Luo Sara Busacca Alan Dawson Krishna Kalyan Kolluri | 2020/8/15 |
EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilisation and accelerated migration through NEK9 and NEK7 | Andrew Fry Laura O'Regan G Barone R Adib CG Woo | 2020/3/17 | |
Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface | Proceedings of the National Academy of Sciences | Uddhav K Shigdel Seung-Joo Lee Mathew E Sowa Brian R Bowman Keith Robison | 2020/7/21 |
2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase | RSC Medicinal Chemistry | Christopher J Matheson Christopher R Coxon Richard Bayliss Kathy Boxall Benoit Carbain | 2020 |
The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure | Nature communications | Robert E Turnbull Louise Fairall Almutasem Saleh Emma Kelsall Kyle L Morris | 2020/6/26 |
Phase-separation of EML4-ALK variant 3 is dependent upon an active ALK conformation | BioRxiv | Josephina Sampson Mark W Richards Jene Choi Andrew M Fry Richard Bayliss | 2020/6/11 |
Genomic discovery of an evolved, genetically programmable modality for selective small-molecule targeting of an intractable protein surface | Andrew Fry | 2020/6/5 |
