Andrew Flyak

Andrew Flyak

California Institute of Technology

H-index: 22

North America-United States

About Andrew Flyak

Andrew Flyak, With an exceptional h-index of 22 and a recent h-index of 22 (since 2020), a distinguished researcher at California Institute of Technology, specializes in the field of Immunology, Structural virology, Vaccine development, Hepatitis C virus.

His recent articles reflect a diverse array of research interests and contributions to the field:

Nucleoside-modified mRNA-lipid nanoparticle lineage vaccine for hepatitis C virus

Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance

Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection

Hepatitis C virus gene sequences and methods of use therefor

Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency

Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals

Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization

B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection

Andrew Flyak Information

University

Position

___

Citations(all)

2347

Citations(since 2020)

1761

Cited By

1264

hIndex(all)

22

hIndex(since 2020)

22

i10Index(all)

29

i10Index(since 2020)

29

Email

University Profile Page

Google Scholar

Andrew Flyak Skills & Research Interests

Immunology

Structural virology

Vaccine development

Hepatitis C virus

Top articles of Andrew Flyak

Nucleoside-modified mRNA-lipid nanoparticle lineage vaccine for hepatitis C virus

2023/5/30

Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance

Immunity

2024/4/9

Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection

Immunity

2024/1/9

Hepatitis C virus gene sequences and methods of use therefor

2023/3/7

Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency

The Journal of Clinical Investigation

2022/8/1

Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals

2022/6/8

Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization

Immunity

2022/2/8

B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection

PloS pathogens

2022/1/6

Mechanisms of HCV resistance to broadly neutralizing antibodies

2021/10/1

Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations

Immunity

2021/8/10

Antibody-mediated neutralization of ebolaviruses

2021/7/6

Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies

Cell reports

2021/4/13

SARS-CoV-2 B cell receptor signatures in at-risk populations

The Journal of Clinical Investigation

2021/1/4

Antibody-mediated neutralization of marburg virus

2021/10/21

Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells

Proceedings of the National Academy of Sciences

2020/7/21

Antibody-mediated neutralization of Ebola viruses

2020/4/14

An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein

Elife

2020/3/3

See List of Professors in Andrew Flyak University(California Institute of Technology)