Andreas Heger

In this Article, we reported genome sequencing data from five Sumatran and five Bornean orang-utans. In re-analysing these data, Banes et al. 1 found that eight of the ten samples were mislabelled, and we wish to correct the original publication according to their findings. In addition, Banes et al. 1 find that one of the orang-utans that we had labelled as a male Sumatran is in fact a female Tapanuli orang-utan (an orang-utan species that was unknown at the time of publication of our original Article and that was first reported in 2017 (ref. 2)). While we here correct the original tables to display the correct names and IDs of the individuals studied, we do not correct the analyses in the original paper since the Tapanuli species was discovered only after we had concluded our study. We refer the reader to Banes et al. 1 for further information. In the main text, the sentence “We also sequenced the genomes of 10 additional …

Genetic risk factors contribute to cardiovascular disease (CVD) risk and are imperfectly captured by family history. The development of integrated risk tools (IRT) that integrate polygenic risk scores (PRS) with conventional risk factors enables improved risk assessment. However, IRTs rely on accurate estimation of the genetic component across millions of genetic variants, either typed or imputed. To support two real-world implementations of CVD IRTs, we present analytical validation data for three biosample types (whole blood, saliva and buccal swab samples) and two genetic assay technologies (a custom-designed genotyping array (845,608 markers) and low pass whole genome sequencing (lpWGS) with 1.8x average read depth, both combined with computational imputation) across 48 ethnically-diverse donors. IRT measurements (range 4%-23%) were performed on the 10-year CVD risk percentage scale …

Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search PMC Full-Text Archive Search in PMC Advanced Search User Guide Journal List ISME J v.14(3); 2020 Mar PMC7058123 Other Formats PDF (205K) Actions Cite Collections Share Permalink Copy RESOURCES Similar articles Cited by other articles Links to NCBI Databases Journal List ISME J v.14(3); 2020 Mar PMC7058123 As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more: PMC Disclaimer | PMC Copyright Notice Logo of ismej ISME J. 2020 Mar; 14(3): 879. Published online 2019 Nov 20. doi: …