Amedeo Caflisch

Amedeo Caflisch

Universität Zürich

H-index: 85

Europe-Switzerland

About Amedeo Caflisch

Amedeo Caflisch, With an exceptional h-index of 85 and a recent h-index of 42 (since 2020), a distinguished researcher at Universität Zürich, specializes in the field of Molecular dynamics, drug design.

His recent articles reflect a diverse array of research interests and contributions to the field:

AI is a viable alternative to high throughput screening: a 318-target study

Structure-based Design of CBP/EP300 Degraders: When Coopera-tivity Overcomes Affinity

Development of a novel class of CBP/EP300 bromodomain inhibitors which block TNF-α induced NFκB signaling

The catalytic mechanism of the RNA methyltransferase METTL3

Proteolysis Targeting Chimera Degraders of the METTL3–14 m6A-RNA Methyltransferase

Small-molecule inhibitors of the m7G-RNA writer METTL1

Structure-based design of a potent and selective YTHDC1 ligand

Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors

Amedeo Caflisch Information

University

Position

Department of Biochemistry

Citations(all)

28555

Citations(since 2020)

9742

Cited By

22659

hIndex(all)

85

hIndex(since 2020)

42

i10Index(all)

238

i10Index(since 2020)

142

Email

University Profile Page

Google Scholar

Amedeo Caflisch Skills & Research Interests

Molecular dynamics

drug design

Top articles of Amedeo Caflisch

AI is a viable alternative to high throughput screening: a 318-target study

Scientific Reports

2024/4/2

Structure-based Design of CBP/EP300 Degraders: When Coopera-tivity Overcomes Affinity

2024/3/26

Development of a novel class of CBP/EP300 bromodomain inhibitors which block TNF-α induced NFκB signaling

2024/3/26

Vlad Pascanu
Vlad Pascanu

H-Index: 11

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

The catalytic mechanism of the RNA methyltransferase METTL3

eLife

2023/11/30

Proteolysis Targeting Chimera Degraders of the METTL3–14 m6A-RNA Methyltransferase

JACS Au

2024/2/12

Valeria Romanucci
Valeria Romanucci

H-Index: 13

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Small-molecule inhibitors of the m7G-RNA writer METTL1

ACS Bio & Med Chem Au

2023/12/12

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Structure-based design of a potent and selective YTHDC1 ligand

2023/11/29

Yaozong Li
Yaozong Li

H-Index: 10

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors

J. Chem. Inf. Model.

2023/10/6

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Matteo Salvalaglio
Matteo Salvalaglio

H-Index: 19

Reevaluation of bromodomain ligands targeting BAZ2A

Protein Science

2023/9

Andrea Unzue
Andrea Unzue

H-Index: 6

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Disrupting dimeric β-amyloid by electric fields

ACS Physical Chemistry Au

2023/7/12

Yang Zhang
Yang Zhang

H-Index: 3

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Optimized reaction coordinates for analysis of enhanced sampling

The Journal of Chemical Physics

2023/7/7

Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3

ACS bio & med chem Au

2023/6/14

Yaozong Li
Yaozong Li

H-Index: 10

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Decrypting Integrins by Mixed-Solvent Molecular Dynamics Simulations

Journal of Chemical Information and Modeling

2023/6/13

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity

Brain Pathology

2023/3

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Adriano Aguzzi
Adriano Aguzzi

H-Index: 65

Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay

International journal of biological macromolecules

2023/1/31

Antibody binding increases the flexibility of the prion protein

Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics

2022/11/1

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Spiking burstiness and working memory in the human medial temporal lobe

Cerebral Cortex Communications

2022/10/1

Andreas Vitalis
Andreas Vitalis

H-Index: 18

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Interactions of Curcumin’s Degradation Products with the Aβ42 Dimer: A Computational Study

The Journal of Physical Chemistry B

2022/9/23

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Domino effect in allosteric signaling of peptide binding

Journal of Molecular Biology

2022/9/15

Amedeo Caflisch
Amedeo Caflisch

H-Index: 43

Identification of BAZ2A bromodomain hit compounds

Acta Crystallographica Section A: Foundations and Advances

2022/8/23

See List of Professors in Amedeo Caflisch University(Universität Zürich)

Co-Authors

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