Alexandre ORTHWEIN
McGill University
H-index: 20
North America-Canada
Top articles of Alexandre ORTHWEIN
The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2
Molecular and Cellular Biology
2024/1/20
FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair
Science Advances
2023/8/9
Julien Dessapt
H-Index: 1
Jean-François Côté
H-Index: 5
Jean-Yves Masson
H-Index: 36
Alexandre Orthwein
H-Index: 16
The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma
Blood advances
2023/7/25
Remya Nair
H-Index: 9
John Heath
H-Index: 5
Ivan Topisirovic
H-Index: 42
Laura Hulea
H-Index: 15
Alexandre Orthwein
H-Index: 16
B cell-specific knockout of AID protects against atherosclerosis
Scientific Reports
2023/5/30
France Dierick
H-Index: 4
Alexandre Orthwein
H-Index: 16
EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax
Journal of Experimental & Clinical Cancer Research
2022/12/9
Systematic proximal mapping of the classical RAD51 paralogs unravel functionally and clinically relevant interactors for genome stability
PLoS Genetics
2022/11/14
Alexandre Orthwein
H-Index: 16
C1orf112 is a novel regulator of interstrand crosslink that decreases FIGNL1-RAD51 interaction
bioRxiv
2022/10/6
In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies
Blood Advances
2022/9/13
Multi-omics data integration analysis identifies the spliceosome as a key regulator of DNA double-strand break repair
NAR cancer
2022/6/1
Silencing PEX26 as an unconventional mode to kill drug-resistant cancer cells and forestall drug resistance
Autophagy
2022/3/4
A decade of RAD51C and RAD51D germline variants in cancer
2022/3
Alexandre Orthwein
H-Index: 16
Homologous recombination factors
2022/3/1
POGZ promotes homology‐directed DNA repair in an HP1‐dependent manner
EMBO reports
2022/1/5
John Heath
H-Index: 5
Martin Karam
H-Index: 5
Michael Witcher
H-Index: 16
Stéphane Richard
H-Index: 42
Alexandre Orthwein
H-Index: 16
GENOME-WIDE CRISPR SCREENING IDENTIFIES THE E3 UBIQUITIN LIGASE HERC1 AS A MODULATOR OF THE RESPONSE TO NUCLEOSIDE ANALOGS IN ACUTE MYELOID LEUKEMIA
Experimental Hematology
2022/9/4
William Wai Lam Poon
H-Index: 0
Alexandre Orthwein
H-Index: 16
3106–GENOME-WIDE CRISPR SCREENING IDENTIFIES THE E3 UBIQUITIN LIGASE HERC1 AS A MODULATOR OF THE RESPONSE TO NUCLEOSIDE ANALOGS IN ACUTE MYELOID LEUKEMIA
Experimental Hematology
2022/1/1
William Wai Lam Poon
H-Index: 0
Alexandre Orthwein
H-Index: 16
3157–GENOME-WIDE CRISPR SCREENING IDENTIFIES THE MITOCHONDRIAL PYRUVATE CARRIER AS A MODULATOR OF BORTEZOMIB IN MULTIPLE MYELOMA
Experimental Hematology
2022/1/1
Alexandre Orthwein
H-Index: 16
Current gene panels account for nearly all homologous recombination repair-associated multiple-case breast cancer families
NPJ Breast Cancer
2021/8/25
POGZ modulates the DNA damage response in a HP1-dependent manner
bioRxiv
2021/6/28
John Heath
H-Index: 5
Martin Karam
H-Index: 5
Michael Witcher
H-Index: 16
Stéphane Richard
H-Index: 42
Alexandre Orthwein
H-Index: 16
Common clonal origin of chronic myelomonocytic leukemia and B-cell acute lymphoblastic leukemia in a patient with a germline CHEK2 variant
Molecular Case Studies
2021/6/1
John Heath
H-Index: 5
Alexandre Orthwein
H-Index: 16
FHL2 Is Essential for Spleen T Cell–Dependent B Cell Activation and Antibody Response
ImmunoHorizons
2020/5/1
