Alex S. Holehouse

Alex S. Holehouse

Washington University in St. Louis

H-index: 40

North America-United States

About Alex S. Holehouse

Alex S. Holehouse, With an exceptional h-index of 40 and a recent h-index of 37 (since 2020), a distinguished researcher at Washington University in St. Louis, specializes in the field of Disordered Proteins, Computational Biophysics, Unstructural Bioinformatics, Quantitative Cell.

His recent articles reflect a diverse array of research interests and contributions to the field:

Disordered proteins interact with the chemical environment to tune their protective function during drying

The molecular basis for cellular function of intrinsically disordered protein regions

Disordered clock protein interactions and charge blocks turn an hourglass into a persistent circadian oscillator

Helicity of a tardigrade disordered protein contributes to its protective function during desiccation

Phase transition of GvpU regulates gas vesicle clustering in bacteria

Structural biases in disordered proteins are prevalent in the cell

The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA

Wrapping of single-stranded DNA by Replication Protein A and modulation through phosphorylation

Alex S. Holehouse Information

University

Position

Assistant Professor

Citations(all)

9768

Citations(since 2020)

9144

Cited By

3461

hIndex(all)

40

hIndex(since 2020)

37

i10Index(all)

63

i10Index(since 2020)

60

Email

University Profile Page

Washington University in St. Louis

Google Scholar

View Google Scholar Profile

Alex S. Holehouse Skills & Research Interests

Disordered Proteins

Computational Biophysics

Unstructural Bioinformatics

Quantitative Cell

Top articles of Alex S. Holehouse

Title

Journal

Author(s)

Publication Date

Disordered proteins interact with the chemical environment to tune their protective function during drying

bioRxiv

Shraddha KC

Kenny H Nguyen

Vincent Nicholson

Annie Walgren

Tony Trent

...

2024

The molecular basis for cellular function of intrinsically disordered protein regions

Alex S Holehouse

Birthe B Kragelund

2024/3

Disordered clock protein interactions and charge blocks turn an hourglass into a persistent circadian oscillator

Nature Communications

Meaghan S Jankowski

Daniel Griffith

Divya G Shastry

Jacqueline F Pelham

Garrett M Ginell

...

2024/4/25

Helicity of a tardigrade disordered protein contributes to its protective function during desiccation

Protein Science

Sourav Biswas

Edith Gollub

Feng Yu

Garrett Ginell

Alex Holehouse

...

2024/2

Phase transition of GvpU regulates gas vesicle clustering in bacteria

Nature microbiology

Zongru Li

Qionghua Shen

Emery T Usher

Andrew P Anderson

Manuel Iburg

...

2024/3/29

Structural biases in disordered proteins are prevalent in the cell

Nature Structural & Molecular Biology

David Moses

Karina Guadalupe

Feng Yu

Eduardo Flores

Anthony R Perez

...

2024/1/4

The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA

Jasmine Cubuk

Jhullian J Alston

J Jeremías Incicco

Alex S Holehouse

Kathleen B Hall

...

2023

Wrapping of single-stranded DNA by Replication Protein A and modulation through phosphorylation

bioRxiv

Rahul Chadda

Vikas Kaushik

Iram Munir Ahmad

Jaigeeth Deveryshetty

Alex S Holehouse

...

2024

Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain

bioRxiv

James L Shepherdson

David M Granas

Jie Li

Zara Shariff

Stephen P Plassmeyer

...

2024

Direct prediction of intrinsically disordered protein conformational properties from sequence

Biophysical Journal

Jeffrey M Lotthammer

Garrett M Ginell

Daniel Griffith

Ryan Emenecker

Alex S Holehouse

2024/2/8

Helicity of a tardigrade disordered protein promotes desiccation tolerance

bioRxiv

Sourav Biswas

Edith Gollub

Feng Yu

Garrett Ginell

Alex S Holehouse

...

2023

FIREBALL: A tool to fit protein phase diagrams based on mean-field theories for polymer solutions

Biophysical Journal

Mina Farag

Alex S Holehouse

Xiangze Zeng

Rohit V Pappu

2023/6/20

Virus induced membraneless organelles and biomolecular condensates

Journal of Molecular Biology

Andrew J Mouland

Leslie Parent

Stephanie C Weber

Alex S Holehouse

2023/8/15

Stress granules offer first aid for leaky organelles

Stephen P Plassmeyer

Alex S Holehouse

2023/11/30

Labile assembly of a tardigrade protein induces biostasis

bioRxiv

Silvia Sanchez-Martinez

Kenny Nguyen

Sourav Biswas

Vincent Nicholson

Andrey V Romanyuk

...

2023

Poly (A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates

Molecular cell

Steven Boeynaems

Yanniv Dorone

Yanrong Zhuang

Victoria Shabardina

Guozhong Huang

...

2023/6/15

SHEPHARD: a modular and extensible software architecture for analyzing and annotating large protein datasets

Bioinformatics

Garrett M Ginell

Aidan J Flynn

Alex S Holehouse

2023/8/1

Dissecting the biophysics and biology of intrinsically disordered proteins

Priya R Banerjee

Alex S Holehouse

Richard Kriwacki

Paul Robustelli

Hao Jiang

...

2023/11/8

The analytical Flory random coil is a simple-to-use reference model for unfolded and disordered proteins

The Journal of Physical Chemistry B

Jhullian J Alston

Garrett M Ginell

Andrea Soranno

Alex S Holehouse

2023/5/18

SOURSOP: A Python package for the analysis of simulations of intrinsically disordered proteins

Journal of Chemical Theory and Computation

Jared M Lalmansingh

Alex T Keeley

Kiersten M Ruff

Rohit V Pappu

Alex S Holehouse

2023/7/18

See List of Professors in Alex S. Holehouse University(Washington University in St. Louis)

Co-Authors

H-index: 78
Rohit V. Pappu

Rohit V. Pappu

Washington University in St. Louis

H-index: 75
Michael Rosen

Michael Rosen

University of Texas Southwestern Medical Center

H-index: 62
Simon Alberti

Simon Alberti

Technische Universität Dresden

H-index: 24
Andreas Vitalis

Andreas Vitalis

Universität Zürich

H-index: 23
Andrea Soranno

Andrea Soranno

Washington University in St. Louis

H-index: 19
Shahar Sukenik

Shahar Sukenik

University of California, Merced

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