Alex K. Shalek
Massachusetts Institute of Technology
H-index: 67
North America-United States
Top articles of Alex K. Shalek
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
B-cell-directed CAR-T cell therapy activates CD8+ cytotoxic CARneg bystander T-cells in non-human primates and patients | Blood | James Kaminski Ryan A Fleming Francesca Alvarez-Calderon Marlana B Winschel Connor McGuckin | 2024/4/3 |
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity | bioRxiv | Valerie Lensch Adele Gabba Robert Hincapie Sachin H Bhagchandani Ankit Basak | 2024 |
Pro-inflammatory feedback loops define immune responses to pathogenic Lentivirus infection | Genome Medicine | Aaron J Wilk Joshua O Marceau Samuel W Kazer Ira Fleming Vincent N Miao | 2024/2/5 |
A knockoff calibration method to avoid over-clustering in single-cell RNA-sequencing | bioRxiv | Alan DenAdel Michelle L Ramseier Andrew W Navia Alex K Shalek Srivatsan Raghavan | 2024 |
Dissecting acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma | Cancer Research | Julien Dilly Laleh Abbassi Connor J Hennessey Giselle A Uribe Brendan Parent | 2024/3/22 |
Abstract A078: Response and resistance to KRAS inhibition in PDAC mouse models | Cancer Research | Laleh Abbassi Jullien Dilly Annan Yang Giselle Uribe Branden Parent | 2024/1/16 |
Dissecting tumor-immune interaction in response and resistance to immune checkpoint blockade in metastatic melanoma | Cancer Research | Giuseppe Tarantino Yiwen He Priyanka Solanky Aaron Thorner Tyler Aprati | 2024/3/22 |
Epstein-Barr Virus Orchestrates Spatial Reorganization and Immunomodulation within the Classic Hodgkin Lymphoma Tumor Microenvironment | bioRxiv | Yao Yu Yeo Huaying Qiu Yunhao Bai Bokai Zhu Yuzhou Chang | 2024 |
Abstract C058: Identifying cell-intrinsic drivers of transcriptional plasticity in pancreatic cancer | Cancer Research | Yuzhou Evelyn Tong Walaa E Katan Alex Bott Julia Joung Alex K Shalek | 2024/1/16 |
B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles | Rob Krause Paul Ogongo Liku Tezera Mohamed Ahmed Ian Mbano | 2023/11/1 | |
A Spatial Multi-Modal Dissection of Host-Microbiome Interactions within the Colitis Tissue Microenvironment | bioRxiv | Bokai Zhu Yunhao Bai Yao Yu Yeo Xiaowei Lu Xavier Rovira-Clavé | 2024 |
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection | Microbiology Spectrum | Carly GK Ziegler Anna H Owings Michelle Galeas-Pena Samuel W Kazer Vincent N Miao | 2024/4/30 |
Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data | bioRxiv | Chibuikem Nwizu Madeline Hughes Michelle L Ramseier Andrew Navia Alex K Shalek | 2024 |
Comparative analysis of cell–cell communication at single-cell resolution | Nature Biotechnology | Aaron J Wilk Alex K Shalek Susan Holmes Catherine A Blish | 2024/3 |
Abstract A093: Deciphering acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma | Cancer Research | Julien Dilly Laleh Abbassi Connor J Hennessey Giselle A Uribe Brendan Parent | 2024/1/16 |
Methods of stratifying and treating coronavirus infection | 2024/4/25 | ||
Congenital T cell activation impairs transitional to follicular B cell maturation in humans | bioRxiv | Hugues Allard-Chamard Kirsty Hillier Michelle L Ramseier Alice Bertocchi Naoki Kaneko | 2024 |
Markers of active hiv reservoir | 2023/10/10 | ||
Compositions and methods for treating bacterial infections | 2024/1/9 | ||
Compressed phenotypic screens for complex multicellular models and high-content assays | bioRxiv | Benjamin E Mead Conner Kummerlowe Nuo Liu Walaa E Kattan Thomas Cheng | 2023/1/23 |