Aleksander S. Popel
Johns Hopkins University
H-index: 84
North America-United States
Top articles of Aleksander S. Popel
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Signaling-biophysical modeling unravels mechanistic control of red blood cell phagocytosis by macrophages in sickle cell disease | PNAS Nexus | Yu Zhang Yuhao Qiang He Li Guansheng Li Lu Lu | 2024/1/20 |
Bi-level Graph Learning Unveils Prognosis-Relevant Tumor Microenvironment Patterns from Breast Multiplexed Digital Pathology | bioRxiv | Zhenzhen Wang Cesar A Santa-Maria Aleksander S Popel Jeremias Sulam | 2024 |
Eliciting the antitumor immune response with a conditionally activated PD‐L1 targeting antibody analyzed with a quantitative systems pharmacology model | CPT: Pharmacometrics & Systems Pharmacology | Alberto Ippolito Hanwen Wang Yu Zhang Vahideh Vakil Hojjat Bazzazi | 2024/1 |
Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth | Cell Death Discovery | Natsuki Furukawa Wendy Yang Alex R Chao Akash Patil Adam C Mirando | 2024/4/2 |
Integrating spatial multi-omics data with spatial quantitative pharmacology (spQSP) model to simulate human neoadjuvant immunotherapy clinical trial of hepatocellular carcinoma | Cancer Research | Shuming Zhang Atul Deshpande Babita K Verma Hanwen Wang Haoyang Mi | 2024/3/22 |
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling | arXiv preprint arXiv:2403.03335 | Hanwen Wang Theinmozhi Arulraj Alberto Ippolito Aleksander S Popel | 2024/3/5 |
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces | Cell systems | Atul Deshpande Melanie Loth Dimitrios N Sidiropoulos Shuming Zhang Long Yuan | 2023/4/19 |
Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager | Frontiers in Pharmacology | Samira Anbari Hanwen Wang Yu Zhang Jun Wang Minu Pilvankar | 2023/6/20 |
Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells | npj Systems Biology and Applications | Min Song Youli Wang Brian H Annex Aleksander S Popel | 2023/9/21 |
Combining multikinase tyrosine kinase inhibitors targeting the vascular endothelial growth factor and cluster of differentiation 47 signaling pathways is predicted to increase … | ACS Pharmacology & Translational Science | Yu Zhang Aleksander S Popel Hojjat Bazzazi | 2023/4/18 |
Methods for identifying and preparing pharmaceutical agents for activating Tie1 and/or Tie2 receptors | 2023/6/13 | ||
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence | Genome medicine | Shuming Zhang Long Yuan Ludmila Danilova Guanglan Mo Qingfeng Zhu | 2023/9/18 |
Predicting response to PD-L1 inhibition in NSCLC using a quantitative systems pharmacology model guided by immunogenomic data | Cancer Research | Hanwen Wang Theinmozhi Arulraj Aleksander S Popel | 2023/4/4 |
Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition | NPJ Precision Oncology | Hanwen Wang Theinmozhi Arulraj Holly Kimko Aleksander S Popel | 2023/6/8 |
Vascular phenotyping of the invasive front in breast cancer using a 3D angiogenesis atlas | Microvascular Research | Akanksha Bhargava Aleksander S Popel Arvind P Pathak | 2023/9/1 |
Anti-angiogenic collagen IV-derived peptide target engagement with αvβ3 and α5β1 in ocular neovascularization models | Iscience | Raquel Lima e Silva Adam C Mirando Stephany Y Tzeng Jordan J Green Aleksander S Popel | 2023/2/17 |
Quantifying Intratumoral Heterogeneity and Immunoarchitecture Generated In-Silico by a Spatial Quantitative Systems Pharmacology Model | Cancers | Mehdi Nikfar Haoyang Mi Chang Gong Holly Kimko Aleksander S Popel | 2023/5/13 |
Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial | bioRxiv | Shuming Zhang Atul Deshpande Babita K Verma Hanwen Wang Haoyang Mi | 2023/8/15 |
Gel-forming therapeutic peptide exhibits sustained delivery and efficacy in a mouse model of triple-negative breast cancer | Peptides | Akash Patil Adam C Mirando Ioanna Liatsou George Sgouros Aleksander S Popel | 2023/11/1 |
Spatial and Compositional Biomarkers in Tumor Microenvironment Predicts Clinical Outcomes in Triple-Negative Breast Cancer | bioRxiv | Haoyang Mi Ravi Varadhan Ashley M Cimino-Mathews Leisha A Emens Cesar A Santa-Maria | 2023 |
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