Alan Smrcka

Alan Smrcka

University of Michigan

H-index: 63

North America-United States

About Alan Smrcka

Alan Smrcka, With an exceptional h-index of 63 and a recent h-index of 32 (since 2020), a distinguished researcher at University of Michigan, specializes in the field of Signal transduction, G proteins.

His recent articles reflect a diverse array of research interests and contributions to the field:

A PACAP-activated network for secretion requires coordination of Ca 2+ influx and Ca 2+ mobilization

Biophysical characterization of the CXC chemokine receptor 2 ligands

Stabilization of Interdomain Interactions in G protein α Subunits as a Determinant of Gαi Subtype Signaling Specificity

Phospholipase C epsilon-1 (PLCƐ1) mediates macrophage activation and protection against tuberculosis

Blockade of selective Gβγ signaling pathway by gallein decreases development of opioid tolerance

Phospholipase C‐ε defines a PACAP‐stimulated pathway for secretion in the chromaffin cell

A Small Contribution to a Large System: The Leptin Receptor Complex

Internalized β2-Adrenergic Receptors Inhibit Subcellular Phospholipase C-Dependent Cardiac Hypertrophic Signaling

Alan Smrcka Information

University

Position

Professor of Pharmacology

Citations(all)

14929

Citations(since 2020)

3159

Cited By

13389

hIndex(all)

63

hIndex(since 2020)

32

i10Index(all)

115

i10Index(since 2020)

79

Email

University Profile Page

University of Michigan

Google Scholar

View Google Scholar Profile

Alan Smrcka Skills & Research Interests

Signal transduction

G proteins

Top articles of Alan Smrcka

Title

Journal

Author(s)

Publication Date

A PACAP-activated network for secretion requires coordination of Ca 2+ influx and Ca 2+ mobilization

bioRxiv

Xiaohuan Chen

Nicole A Bell

Breanna L Coffman

Agustin A Rabino

Rafael Garcia-Mata

...

2024/1/3

Biophysical characterization of the CXC chemokine receptor 2 ligands

Plos one

Patrick Martin

Emily A Kurth

David Budean

Nathalie Momplaisir

Elaine Qu

...

2024/4/16

Stabilization of Interdomain Interactions in G protein α Subunits as a Determinant of Gαi Subtype Signaling Specificity

bioRxiv

Tyler J Lefevre

Wenyuan Wei

Elizaveta Mukhaleva

Sai Pranathi Meda Venkata

Naincy R Chandan

...

2023/4/6

Phospholipase C epsilon-1 (PLCƐ1) mediates macrophage activation and protection against tuberculosis

Infection and Immunity

Ananya Gupta

Shyamala Thirunavukkarasu

Javier Rangel-Moreno

Mushtaq Ahmed

Rosemary V Swanson

...

2024/3/7

Blockade of selective Gβγ signaling pathway by gallein decreases development of opioid tolerance

Alan V Smrcka

Gissell Sanchez

Emily MM Jutkiewicz

2023/6/1

Phospholipase C‐ε defines a PACAP‐stimulated pathway for secretion in the chromaffin cell

Journal of neuroendocrinology

Xiaohuan Chen

Breanna L Coffman

Rebecca L Brindley

Jason D Galpin

Christopher A Ahern

...

2023/11

A Small Contribution to a Large System: The Leptin Receptor Complex

The Journal of Physical Chemistry B

Jennifer M Simien

Grace E Orellana

Hoa TN Phan

Yao Hu

Emily A Kurth

...

2023/3/13

Internalized β2-Adrenergic Receptors Inhibit Subcellular Phospholipase C-Dependent Cardiac Hypertrophic Signaling

bioRxiv

Wenhui Wei

Alan V Smrcka

2023/6/9

Identification of a sequence of the activity-dependent neuroprotective protein (ADNP) that is necessary for its interaction with G?? i1

Nathalie Momplaisir

Naincy R Chandan

Alan V Smrcka

2023/6/1

SMARCD3: A Link Between G?? q and Chromatin Remodeling?

Joseph Loomis

Naincy R Chandan

Alan V Smrcka

2023/6/1

Opposing effects of ß2-ARs on ß1-ARs on phospholipase C-mediated cardiac hypertrophic signaling

Wenhui Wei

Alan V Smrcka

2023/6/1

A network of Gαi signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF

Science signaling

Naincy R Chandan

Saji Abraham

Shuvasree SenGupta

Carole A Parent

Alan V Smrcka

2022/1/18

Signaling, Physiology, and Targeting of GPCR‐Regulated Phospholipase C Enzymes

GPCRs as Therapeutic Targets

Naincy R Chandan

Alan V Smrcka

Hoa TN Phan

2022/11/1

Subcellular β-adrenergic receptor signaling in cardiac physiology and disease

Journal of cardiovascular pharmacology

Wenhui Wei

Alan V Smrcka

2022/9/1

A naturally occurring membrane-anchored Gαs variant, XLαs, activates phospholipase Cβ4

Journal of Biological Chemistry

Hoa TN Phan

Joseph Loomis

Saji Abraham

Qing He

Murat Bastepe

...

2022/8/1

PACAP and acetylcholine cause distinct Ca2+ signals and secretory responses in chromaffin cells

Journal of General Physiology

Alina Morales

Ramkumar Mohan

Xiaohuan Chen

Breanna L Coffman

Mounir Bendahmane

...

2022/12/20

Identification of the Activity‐Dependent Neuroprotective Protein (ADNP) as a Novel Effector of Gαi1

The FASEB Journal

Nathalie L Momplaisir

Naincy Chandan

Tyler Lefevre

Alan V Smrcka

2022/5

Phospholipase Cε insufficiency causes ascending aortic aneurysm and dissection

American Journal of Physiology-Heart and Circulatory Physiology

Douglas K Atchison

Christopher L O’Connor

Kimber Converso-Baran

Ingrid L Bergin

Hongyu Zhang

...

2022/12/1

Identifying Novel Signaling Mechanisms Downstream of Gq‐Coupled Receptors

The FASEB Journal

Joseph F Loomis

Naincy R Chandan

Matthew J Brody

Alan V Smrcka

2022/5

Coincident regulation of PLCβ signaling by Gq-coupled and μ-opioid receptors opposes opioid-mediated antinociception

Molecular pharmacology

Gissell A Sanchez

Emily M Jutkiewicz

Susan Ingram

Alan V Smrcka

2022/12/1

See List of Professors in Alan Smrcka University(University of Michigan)