Abdelkrim BENABBAS

Abdelkrim BENABBAS

North Eastern University

H-index: 15

Asia-Thailand

About Abdelkrim BENABBAS

Abdelkrim BENABBAS, With an exceptional h-index of 15 and a recent h-index of 9 (since 2020), a distinguished researcher at North Eastern University, specializes in the field of Computational Biophysics, Machine learning, Protein Dynamics, Algorithm design, Protein-DNA interactions.

His recent articles reflect a diverse array of research interests and contributions to the field:

Electrical unfolding of cytochrome c during translocation through a nanopore constriction

Proton Tunnelling and Proton-coupled Electron Transfer in Biological Systems: Theory and Experimental Analysis

All‐Optical Helicity‐Dependent Switching in Hybrid Metal–Ferromagnet Thin Films

Single Protein Trapping on Ultrathin Asymmetric Solid-State Nanopores

Abdelkrim BENABBAS Information

University

North Eastern University

Position

Senior Research Scientist

Citations(all)

714

Citations(since 2020)

311

Cited By

561

hIndex(all)

15

hIndex(since 2020)

9

i10Index(all)

21

i10Index(since 2020)

9

Email

University Profile Page

North Eastern University

Abdelkrim BENABBAS Skills & Research Interests

Computational Biophysics

Machine learning

Protein Dynamics

Algorithm design

Protein-DNA interactions

Top articles of Abdelkrim BENABBAS

Electrical unfolding of cytochrome c during translocation through a nanopore constriction

Authors

Prabhat Tripathi,Abdelkrim Benabbas,Behzad Mehrafrooz,Hirohito Yamazaki,Aleksei Aksimentiev,Paul M Champion,Meni Wanunu

Journal

Biophysical Journal

Published Date

2021/2/12

Many small proteins move across cellular compartments through narrow pores. In order to thread a protein through a constriction, free energy must be overcome to either deform or completely unfold the protein. In principle, the diameter of the pore, along with the effective driving force of transport, should be critical factors that govern whether protein translocation proceeds via squeezing, unfolding/threading, or both. To directly probe this, we studied the electric-field-driven translocation behavior of cytochrome c (cyt c) through ultrathin silicon nitride (SiNx) solid-state nanopores of diameters ranging from 1.5 to 5.5 nm. For a 2.5 nm diameter pore we find that in a threshold electric field regime of∼ 30-100 MV/m cyt c is able to squeeze into the pore. Further, as electric fields inside the pore further increase the unfolded state of cyt c is stabilized, facilitating translocation. In contrast, for 1.5 nm and 2 nm diameter pores …

Proton Tunnelling and Proton-coupled Electron Transfer in Biological Systems: Theory and Experimental Analysis

Authors

Paul M Champion,Abdelkrim Benabbas

Published Date

2020/9/22

This chapter discusses various aspects of proton tunnelling in biomolecules. Two experimental model systems are explored in detail: a “proton wire” in green fluorescent protein and proton-coupled electron transfer in the enzyme soybean lipoxygenase. These two systems demonstrate, respectively, the application of electronically adiabatic and electronically non-adiabatic analytic models of proton tunnelling that provide useful insight into methods of experimental data analysis. Surprisingly rapid (sub-nanosecond) time constants are found for the inherent ground-state tunnelling rates at 298 K and it is demonstrated how these absolute rates help to constrain other parameters, particularly for the electronically adiabatic reaction where the agreement between experiment and theory is found to be excellent. Approximations that are often made in analytical models, such as the Born–Oppenheimer separation of heavy …

All‐Optical Helicity‐Dependent Switching in Hybrid Metal–Ferromagnet Thin Films

Authors

Feng Cheng,Zhidong Du,Xinjun Wang,Ziqiang Cai,Lin Li,Chuangtang Wang,Abdelkrim Benabbas,Paul Champion,Nianxiang Sun,Liang Pan,Yongmin Liu

Journal

Advanced Optical Materials

Published Date

2020/7

Over the past decades, optical manipulation of magnetization by ultrafast laser pulses has attracted extensive interest. It not only shows intriguing fundamental science arising from the interactions between spins, electrons, phonons, and photons, but also manifests the potential to process and store data at a speed that is three orders of magnitude faster than the current technologies. In this paper, all‐optical helicity‐dependent switching (AO‐HDS) in hybrid metal–ferromagnet thin films, which consist of Co/Pt multilayers with perpendicular magnetic anisotropy and an Au film capping layer on the top, is experimentally demonstrated. The switching behaviors of the hybrid Co/Pt–Au material, with various laser repetition rates, scanning speeds, and fluencies, are systematically studied. In comparison with bare Co/Pt multilayers, the hybrid metal–ferromagnet thin films show pronounced AO‐HDS when the number of laser …

Single Protein Trapping on Ultrathin Asymmetric Solid-State Nanopores

Authors

Hirohito Yamazaki,Fanjun Li,Abdelkrim Benabbas,Benjamin Cressiot,Paul M Champion,Min Chen,Meni Wanunu

Journal

Biophysical Journal

Published Date

2020/2/7

156a Sunday, February 16, 2020 blockade currents indicate that the different current levels originate from variations in molecular size and trapping orientation. Furthermore, MBP with a chain of 10 aspartic acids (MBP10D), which is highly negatively charged, can be trapped at $250 milliseconds at 140 mV. When maltose is added and binds to MBP10D, the three blockade current levels converge to two, a dominant and a minor level. These levels are attributed to a maltose-bound and an open conformation of MBP. Our single protein trapping method aids in studying protein geometry, as well as studying substrate-induced conformational changes of proteins. 1. Yamazaki, H., R. Hu, Q. Zhao, and M. Wanunu. 2018. Photothermally Assisted Thinning of Silicon Nitride Membranes for Ultrathin Asymmetric Nanopores. ACS Nano 12 (12): 12472-12481.

See List of Professors in Abdelkrim BENABBAS University(North Eastern University)

Abdelkrim BENABBAS FAQs

What is Abdelkrim BENABBAS's h-index at North Eastern University?

The h-index of Abdelkrim BENABBAS has been 9 since 2020 and 15 in total.

What are Abdelkrim BENABBAS's top articles?

The articles with the titles of

Electrical unfolding of cytochrome c during translocation through a nanopore constriction

Proton Tunnelling and Proton-coupled Electron Transfer in Biological Systems: Theory and Experimental Analysis

All‐Optical Helicity‐Dependent Switching in Hybrid Metal–Ferromagnet Thin Films

Single Protein Trapping on Ultrathin Asymmetric Solid-State Nanopores

are the top articles of Abdelkrim BENABBAS at North Eastern University.

What are Abdelkrim BENABBAS's research interests?

The research interests of Abdelkrim BENABBAS are: Computational Biophysics, Machine learning, Protein Dynamics, Algorithm design, Protein-DNA interactions

What is Abdelkrim BENABBAS's total number of citations?

Abdelkrim BENABBAS has 714 citations in total.

What are the co-authors of Abdelkrim BENABBAS?

The co-authors of Abdelkrim BENABBAS are Thomas L. Poulos, Paul M. Champion, Meni Wanunu, Ilia Denisov.

    Co-Authors

    H-index: 98
    Thomas L. Poulos

    Thomas L. Poulos

    University of California, Irvine

    H-index: 62
    Paul M. Champion

    Paul M. Champion

    North Eastern University

    H-index: 48
    Meni Wanunu

    Meni Wanunu

    Northeastern University

    H-index: 43
    Ilia Denisov

    Ilia Denisov

    University of Illinois at Urbana-Champaign

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