AbdelKhalek Samy

AbdelKhalek Samy

Assiut University

H-index: 2

Africa-Egypt

About AbdelKhalek Samy

AbdelKhalek Samy, With an exceptional h-index of 2 and a recent h-index of 2 (since 2020), a distinguished researcher at Assiut University, specializes in the field of Veterinary Sciences, Animal Surgery, Anesthesiology, Radiology.

AbdelKhalek Samy Information

University

Assiut University

Position

Research Fellow

Citations(all)

14

Citations(since 2020)

14

Cited By

0

hIndex(all)

2

hIndex(since 2020)

2

i10Index(all)

0

i10Index(since 2020)

0

Email

University Profile Page

Assiut University

AbdelKhalek Samy Skills & Research Interests

Veterinary Sciences

Animal Surgery

Anesthesiology

Radiology

Top articles of AbdelKhalek Samy

Validation of a new rat model of urethral sphincter injury and leak point pressure measurements

AimsIn vivo experiments were performed to establish and validate a rat model of urethral sphincter injury and to develop a method for leak point pressure (LPP) measurements performed repeatedly in the same animal.MethodsTwenty-four Sprague-Dawley female rats underwent bladder and epidural catheter implantation. Five days later, cystometry was performed using continuous infusion. Anesthesia with isoflurane, ketamine-xylazine (KX) or fentanyl-fluanisone-midazolam (FFM) was used. After three micturition cycles, intrathecal bupivacaine was administered leading to the suppression of reflex bladder contractions. LPP measurements were performed using vertical tilt. After the initial LPP measurement, animals underwent partial resection of the striated urethral sphincter. The effect was evaluated 6 weeks after surgery, by repeating the LPP measurement in the same animal.ResultsTen out of 19 animals …

Authors

Abdelkhalek Samy Abdelkhalek,Patrick D Clarke,Matthew A Sommers,Tyler Oe,Thomas M Andersen,Chrissie T Andersen,Eva Kildall Hejbøl,Henrik Daa Schrøder,Peter Zvara

Journal

Scandinavian Journal of Urology

Published Date

2021/11/2

Anesthetic protocols for urodynamic studies of the lower urinary tract in small rodents—A systematic review

Urodynamic studies in rats and mice are broadly used to examine pathomechnisms of disease and identify and test therapeutic targets. This review aims to highlight the effects of the anesthetics on the lower urinary tract function and seeks to identify protocols that allow recovery from anesthesia and repeated measurements while preserving the function which is being studied. All studies published in English language, which compared the data obtained under various types of anesthesia and the urodynamics performed in awake animals were included. It appears that urethane, an anesthetic recommended extensively for the investigation of lower urinary tract function, is appropriate for acute urodynamic studies only. Major advantages of urethane are its stability and ability to preserve the micturition reflex. Due to its toxicity and carcinogenicity, urethane anesthesia should not be used for recovery procedures. This review evaluated available alternatives including propofol, isoflurane and combinations of urethane, ketamine/xylazine, ketamine/medetomidine, and/or fentanyl/fluanisone/midazolam. Different effects have been demonstrated among these drugs on the urinary bladder, the urethral sphincter, as well as on their neuroregulation. The lowest incidence of adverse effects was observed with the use of a combination of ketamine and xylazine. Although the variations in the reviewed study protocols represent a limitation, we believe that this summary will help in standardizing and optimizing future experiments.

Authors

Abdelkhalek Samy Abdelkhalek,Haroun Ali Youssef,Ahmed Sayed Saleh,Peter Bollen,Peter Zvara

Published Date

2021/6/24

AbdelKhalek Samy FAQs

What is AbdelKhalek Samy's h-index at Assiut University?

The h-index of AbdelKhalek Samy has been 2 since 2020 and 2 in total.

What are AbdelKhalek Samy's top articles?

The articles with the titles of

Validation of a new rat model of urethral sphincter injury and leak point pressure measurements

Anesthetic protocols for urodynamic studies of the lower urinary tract in small rodents—A systematic review

are the top articles of AbdelKhalek Samy at Assiut University.

What are AbdelKhalek Samy's research interests?

The research interests of AbdelKhalek Samy are: Veterinary Sciences, Animal Surgery, Anesthesiology, Radiology

What is AbdelKhalek Samy's total number of citations?

AbdelKhalek Samy has 14 citations in total.

What are the co-authors of AbdelKhalek Samy?

The co-authors of AbdelKhalek Samy are Hamdy F. F. Mahmoud, Prof. Magda Mahmoud Ali Omar.

    Co-Authors

    H-index: 5
    Hamdy F. F. Mahmoud

    Hamdy F. F. Mahmoud

    Virginia Polytechnic Institute and State University

    H-index: 2
    Prof. Magda Mahmoud Ali Omar

    Prof. Magda Mahmoud Ali Omar

    Assiut University

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