Abdelhafeez Moshrif

Abdelhafeez Moshrif

Al-Azhar University

H-index: 10

Africa-Egypt

Abdelhafeez Moshrif Information

University

Al-Azhar University

Position

Assist.Professor of rheumatology Egypt

Citations(all)

394

Citations(since 2020)

383

Cited By

62

hIndex(all)

10

hIndex(since 2020)

10

i10Index(all)

11

i10Index(since 2020)

11

Email

University Profile Page

Al-Azhar University

Abdelhafeez Moshrif Skills & Research Interests

Rheumatology

Top articles of Abdelhafeez Moshrif

Clinical implications of seropositive and seronegative autoantibody status in rheumatoid arthritis patients: A comparative multicentre observational study

Background and Objectives Rheumatoid factor (RF) and anti-cyclic citrullinated protein (anti-CCP) have been used to improve the diagnosis and prognosis of rheumatoid arthritis (RA). However, their association with RA disease phenotypes, individually and in combination, is not well studied. The aim of the study was to compare patients’ and disease characteristics, activity and severity in double seronegative (DNRA), single seropositive RF, single seropositive anti-CCP and double seropositive (DPRA) patients. Methods Adults subjects with RA from Egyptian College of Rheumatology (ECR) database who had RF and anti-CCP results available were included. Demographic, clinical features, disease activity score 28 (DAS28), Health Assessment Questionnaire (HAQ) and laboratory data were collected and compared among different RA groups. Results 5268 RA patients with mean age of 44.9±11.6 years, and …

Authors

Nevin Hammam,Passant N El-Husseiny,Suzan S Al-Adle,Nermeen Samy,Nora Y Elsaid,Dina F El-Essawi,Eman F Mohamed,Samar M Fawzy,Samah A El Bakry,Maha Nassr,Samah I Nasef,Hanan M El-Saadany,Shereen Elwan,Nada M Gamal,Abdelhfeez Moshrif,Osman Hammam,Rawhya R El Shereef,Faten Ismail,Samar Tharwat,Doaa Mosad Mosa,Mervat I Abd Elazeem,Enas A Abdelaleem,Tamer A Gheita,Egyptian College of Rheumatology (ECR) Rheumatoid Arthritis (ECR-RA) Study Group

Journal

Rheumatology and Immunology Research

Published Date

2024/3/31

Clinical and ultrasonogrpahic evaluation of efficacy and safety of intralesional injection of autologous platelet-rich plasma in morphea: A comparative case series

ObjectiveTo evaluate the efficacy and safety of platelet-rich plasma to restore skin changes in morphea by ultrasound and Localized Scleroderma Cutaneous Assessment Tool.MethodsNine morphea patients (21 lesions) were diagnosed clinically and by histopathology. Intradermal platelet-rich plasma was injected into morphea lesion once weekly for 12 sessions. The disease severity and damage were evaluated at baseline, after the last session (3 months later), and at 6 months follow-up using the LoSCAT and a high-resolution ultrasound. The healthy corresponding side was considered as a control.ResultsThe Localized Scleroderma Cutaneous Assessment Tool score showed a significant improvement starting from 13 ± 7.28 up to 7.33 ± 6.82 after the therapeutic endpoint, reaching to 6.44 ± 7.09 after 6 months of follow-up with p value = 0.008 and 0.014, respectively. There was a significant positive …

Authors

Esraa Elnaquip,Mahmoud Makki,Mofreh Mansour,Abdelhfeez Moshrif

Journal

Journal of Scleroderma and Related Disorders

Published Date

2024

Evaluating the Effect of Delayed Diagnosis on Disease Outcome in Fibromyalgia: A Multi-Center Cross-Sectional Study

BackgroundThe impact of delayed diagnosis (DD) on fibromyalgia (FM) patients’ symptomatology and disease outcome has not yet been systematically studied.ObjectiveTo analyze the predictors of DD and the influence of DD on FM aggravation and disease evaluation measures.Methods370 FM patients were interviewed prospectively for this study. The following information was obtained: DD, widespread pain index (WPI), symptom severity scale (SSS), polysymptomatic distress scale (PDS) scale (SSS + WPI), and tender points. We identified three groups of patients: early diagnosis (ED: 2 years; 83 patients), late diagnosis (LD: > 2–7 years; 198 patients), and very late diagnosis (VLD: > 7 years; 89 patients).ResultsThe patients’ average age was 33.9 (9.8) years, and 79% were female. The SSS, PDS, and tender point means were 7.8 (1.6), 16.46 (4.1), and 14.31 (2.3), respectively. The correlation between DD and …

Authors

Abdelhfeez Moshrif,Ahmed Mosallam,Mohammed Hassan Abu-Zaid,Wesam Gouda

Journal

Journal of Pain Research

Published Date

2023/12/31

POS1347 EVALUATING THE EFFICACY OF LOCAL CORTICOSTEROID INJECTION, PLATELET-RICH PLASMA, AND EXTRACORPOREAL SHOCKWAVE THERAPY IN PATIENTS WITH PES ANSERINE BURSITIS: A PILOT …

Background Pes anserine bursitis is one of the causes of painful knee syndromes. It limits physical activity and impairs the quality of life of a patient. Obesity and osteoarthritis (OA) of the knee are common predisposing factors for pes anserine bursitis. It is treated with non-steroidal anti-inflammatory drugs (NSAIDs), physiotherapy, injections of local anesthetics, and corticosteroids. This study examines the efficacy of local corticosteroid injection, Platelet-rich plasma (PRP) injection, and extracorporeal shock wave therapy (ESWT) as different modalities to alleviate pain and improve function in patients with pes anserine bursitis.Objectives This study examines the efficacy of local corticosteroid injection, Platelet-rich plasma (PRP) injection, and extracorporeal shock wave therapy (ESWT) as different modalities to alleviate pain and improve function in patients with pes anserine bursitis.Methods This randomized …

Authors

WA Gouda,AS Abbas,TM Abdel-Aziz,MZ Shoaeir,A Moshrif,A Mosallam

Published Date

2023/6/1

Ultrasound abnormalities of the major salivary glands in Egyptian patients with systemic sclerosis

Introduction/objectivessystemic sclerosis (SSc) is an autoimmune disorder with multiple organs destruction. This study aimed to identify the ultrasonographic changes of major salivary glands in Egyptian scleroderma patients and to detect their association to different disease manifestations.MethodsForty-seven SSc patients and 43 apparent healthy volunteers were enrolled. Demographics, inflammatory markers, and autoimmune status were recorded. Ultrasound evaluation of salivary glands was performed. Salivary gland changes’ associations were statistically examined with SSc susceptibility and disease manifestations.ResultsThirty-one SSc patients exhibited glandular pathology (p < 0.0001), compared to controls. Of these abnormalities, SSc patients showed a total parotid gray scale of 2, total submandibular gray scale of 2, total glandular gray scale of 4, and total glandular Doppler signal of 1 at p < 0 …

Authors

Ahmed E Hafez,AlShaimaa M Taha,Abdelhfeez Moshrif,Hany M Aly,Rasha Abdel Noor,Mohamed Mortada,Radwa Elkhouli

Journal

Clinical Rheumatology

Published Date

2023/12

Efficacy of Autologous Platelet Rich Plasma on Morphea: A Comparative Clinical and Ultrasonographic Follow-up Study

Despite different modalities for morphea therapy used; it still has a great challenge. This study aimed to evaluate the efficacy and safety of intralesional Autologous Platelet Rich Plasma injection once weekly for 12 sessions to restore skin disfigurement (dyspigmentation, skin atrophy, and adnexal destruction) in nine patients (21 lesions) with a mean duration of 5.96±2.4 years. The disease severity and damage were evaluated by the Localized Scleroderma Cutaneous Assessment Tool (LoSCAT) score; the skin layer thickness and Echogenicity were evaluated by musculoskeletal ultrasound at baseline, 3-month, and 6 months intervals. The LoSCAT score showed a significant improvement with the mean reduction from 13±7.3 to 7.33±6.8 at the end of 3rd month and to 6.44±7.1 at the end of 6th month (p= 0.008 and 0.014) respectively, additionally, the ultrasound showed an increase in the thickness of skin layers from baseline to be nearly equal to normal control (p< 0.001), with transient adverse effects. The present study indicates that PRP is a good tool for the improvement of morphea lesions with a great aesthetic outcome.

Authors

Mahmoud Abdel Sabour Makki,Abdelhfeez Moshrif,Mofreh Mansour,Esraa Elnaquip

Published Date

2023/4/28

Comparing the Efficacy of Local Corticosteroid Injection, Platelet-Rich Plasma, and Extracorporeal Shockwave Therapy in the Treatment of Pes Anserine Bursitis: A Prospective …

Background. Pes anserine bursitis (PAB) is one of the most common causes of painful knee syndromes. This study aimed at examining the efficacy of local corticosteroid injection, platelet-rich plasma (PRP) injection, and extracorporeal shock wave therapy (ESWT) as different modalities to alleviate pain and enhance function in patients with pes anserine bursitis (PAB). Methods. A prospective, randomized, comparative study was conducted on 180 patients diagnosed with chronic PAB. They were equally divided into three groups as follows: Group I received a local corticosteroid injection of 40 mg of methylprednisolone acetate/1 ml; Group II received a PRP injection; and in Group III, ESWT was used. Outcome measures included the visual analog scale (VAS), Western Ontario and McMaster Universities (WOMAC) pain score, WOMAC physical function score, and Ritchie articular index (RAI) for tenderness, which were recorded at the baseline, after 1 week, and after 8 weeks. Results. Before the application of procedures, there was a statistically significant increase in the WOMAC pain score in the local corticosteroid group compared to the PRP group and the ESWT group (). After the application of procedures, there was a statistically significant improvement in the 1-week and 8-week WOMAC pain score, WOMAC physical function score, and VAS in the local corticosteroid group in comparison to the PRP group and the ESWT group. (). Moreover, RAI for tenderness shows statistically significant improvement at 8 weeks in the local corticosteroid groups compared to the PRP groups () and ESWT groups (). Similarly, a statistically significant …

Authors

Wesam Gouda,Awad S Abbas,Tarek M Abdel-Aziz,Mohamed Z Shoaeir,Walid Ahmed,Abdelhfeez Moshrif,Ahmed Mosallam,Mohamed Kamal

Journal

Advances in Orthopedics

Published Date

2023/9/30

Rheumatoid arthritis study of the Egyptian College of Rheumatology (ECR): nationwide presentation and worldwide stance

To depict the spectrum of rheumatoid arthritis (RA) in Egypt in relation to other universal studies to provide broad-based characteristics to this particular population. This work included 10,364 adult RA patients from 26 specialized Egyptian rheumatology centers representing 22 major cities all over the country. The demographic and clinical features as well as therapeutic data were assessed. The mean age of the patients was 44.8 ± 11.7 years, disease duration 6.4 ± 6 years, and age at onset 38.4 ± 11.6 years; 209 (2%) were juvenile-onset. They were 8750 females and 1614 males (F:M 5.4:1). 8% were diabetic and 11.5% hypertensive. Their disease activity score (DAS28) was 4.4 ± 1.4 and health assessment questionnaire (HAQ) 0.95 ± 0.64. The rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) were positive in 73.7% and 66.7% respectively. Methotrexate was the most used …

Authors

Tamer A Gheita,Hala A Raafat,Samah A El-Bakry,Ahmed Elsaman,Hanan M El-Saadany,Nevin Hammam,Iman I El-Gazzar,Nermeen Samy,Nora Y Elsaid,Suzan S Al-Adle,Samar Tharwat,Amira M Ibrahim,Samar M Fawzy,Nahla N Eesa,Rawhya El Shereef,Faten Ismail,Mervat I Abd Elazeem,Enas A Abdelaleem,Amany El-Bahnasawy,Zahraa I Selim,Nada M Gamal,Maha Nassr,Samah I Nasef,Abdel Hafeez Moshrif,Shereen Elwan,Yousra H Abdel-Fattah,Marwa A Amer,Doaa Mosad,Eman F Mohamed,Dina F El-Essawi,Hanan Taha,Mohamed N Salem,Rasha M Fawzy,Maha E Ibrahim,Asmaa Khalifa,Nouran M Abaza,Ahmed M Abdalla,Amany R El-Najjar,Noha A Azab,Hanan M Fathi,Khaled El-Hadidi,Tahsin El-Hadidi,Egyptian College of Rheumatology (ECR) Rheumatoid Arthritis Study Group

Journal

Rheumatology International

Published Date

2023/4

POS1262 ULTRASONOGRPHIC EVALUATION OF SALIVARY GLANDS IN PATIENTS WITH SYSTEMIC SCLEROSIS

Background Although dry mouth is a common symptom in systemic sclerosis (SSc), there is a lack of studies evaluating the salivary glands in this heterogenous systemic disease.Objectives To study the ultrasonographic changes of salivary glands in patients with systemic sclerosis and to correlate these changes with disease activity markers, clinical data and autoantibodies.Methods Forty-seven SSc patients and forty-three healthy age and sex matched controls were studied. Duration of illness, sicca symptoms, Schirmer’s test, joint symptoms, internal organ evaluation including interstial lung disease, pulmonary artery hypertension, Raynaud’s phenomenon, digital pitting scars and the modified Rodnan total skin score. Laboratory investigations included acute phase reactants, antinuclear antibody, Anti-Ro-60/SSA, anti-La/SSB, anti-Topoisomerase 1 (anti–topo I) and anticentromere (ACA). Salivary glands were …

Authors

A Hafez,A Moshrif,H Aly,R Abdelnoor,MA Mortada,R Elkholi

Published Date

2023/6/1

Development of machine learning models for detection of vision threatening Behçet’s disease (BD) using Egyptian College of Rheumatology (ECR)–BD cohort

BackgroundEye lesions, occur in nearly half of patients with Behçet’s Disease (BD), can lead to irreversible damage and vision loss; however, limited studies are available on identifying risk factors for the development of vision-threatening BD (VTBD). Using an Egyptian college of rheumatology (ECR)-BD, a national cohort of BD patients, we examined the performance of machine-learning (ML) models in predicting VTBD compared to logistic regression (LR) analysis. We identified the risk factors for the development of VTBD.MethodsPatients with complete ocular data were included. VTBD was determined by the presence of any retinal disease, optic nerve involvement, or occurrence of blindness. Various ML-models were developed and examined for VTBD prediction. The Shapley additive explanation value was used for the interpretability of the predictors.ResultsA total of 1094 BD patients [71.5% were men, mean …

Authors

Nevin Hammam,Ali Bakhiet,Eiman Abd El-Latif,Iman I El-Gazzar,Nermeen Samy,Rasha A Abdel Noor,Emad El-Shebeiny,Amany R El-Najjar,Nahla N Eesa,Mohamed N Salem,Soha E Ibrahim,Dina F El-Essawi,Ahmed M Elsaman,Hanan M Fathi,Rehab A Sallam,Rawhya R El Shereef,Faten Ismail,Mervat I Abd-Elazeem,Emtethal A Said,Noha M Khalil,Dina Shahin,Hanan M El-Saadany,Marwa ElKhalifa,Samah I Nasef,Ahmed M Abdalla,Nermeen Noshy,Rasha M Fawzy,Ehab Saad,Abdelhafeez Moshrif,Amira T El-Shanawany,Yousra H Abdel-Fattah,Hossam M Khalil,Osman Hammam,Aly Ahmed Fathy,Tamer A Gheita

Journal

BMC Medical Informatics and Decision Making

Published Date

2023/2/17

OP0053 EFFICACY AND SAFETY OF BARICITINIB IN PATIENTS WITH ACTIVE LUPUS NEPHRITIS: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED PHASE 3 TRIAL

Background Baricitinib a selective Janus kinase (JAK) inhibitors 1&2 have been recognized as a potential therapeutic option in systemic lupus (SLE), also known Baricitinib, a JAK inhibitor, has demonstrated efficacy and safety in the treatment of dermatitis and arthritis 1; however, no JAK inhibitor studies have been conducted in lupus nephritis (LN) to dat.e.Objectives To assess the efficacy and safety of Baricitinib in patients (pts) with active LN.Methods The study is a randomized, double-blind, active competitor (cyclophosphamide)-controlled, phase 3 trial registered on clinicaltrials.com (NCT05432531), enrolled adults ≥18 years with a clinical diagnosis of LN (who also fulfilled classification criteria for LN grade III & IV), who had objective signs of active nephritis consistent with persistent proteinuria>0.5 g/day and/or cellular casts at screening, and who had SLEDAI-2K > 4 and patient assessment of anti-ds DNA …

Authors

M Hassanien,A Moshrif,H Hetta

Published Date

2023/6/1

AB0825 EFFICACY OF AUTOLOGOUS PLATELET RICH PLASMA ON MORPHEA: A COMPARATIVE CLINICAL AND ULTRASONOGRAPHIC FOLLOW UP STUDY

Background Morphea is a subtype of limited scleroderma characterized by atrophic changes. There are multiple treatment modalities for morphea, but all have limited success to restore atrophy.Objectives To evaluate the efficacy and safety of paltelet rich plasma (PRP) to restore skin changes in morphea such as (skin atrophy, dyspigmentation and adnexal destruction) by ultrasound and Localized Scleroderma Cutaneous Assessment Tool (LoSCAT).Methods Nine morphea patients (21 lesions) were diagnosed clinically and by histopathology. Intradermal PRP was injected into morphea lesion once weekly for 12 sessions. The disease severity and damage were evaluated at baseline, after the last session (3 months later) and at 6 months follow up using (LoSCAT). Echogenicity and skin layer thickness were measured by musculoskeletal ultrasound with high frequency linear probe.Results The mean age of our …

Authors

E Elnaquip,M Makki,M Mansour,A Moshrif

Published Date

2023/6/1

AB0876 Can ultrasonographic peripheral enthesitis mirror spinal radiographic abnormalities and other disease parameters in patients radiographic axial SpA?

Background Although enthesitis is the hallmark of spondyloarthritides, the association between peripheral enthesitis, radiographic spinal affection and disease assessment parameters is still underestimated.Objectives In this cross-sectional prospective study, we aimed to evaluate the relation of US pattern of peripheral enthesitis with the spinal radiographic changes and other disease parameters in patients with radiographic axial spondyloarthritis (SpA).Methods Fifty-eight patients with radiographic axial SpA (ASAS criteria) were studied for the presence and pattern of peripheral lower limb enthesitis according to the Outcome Measures in Rheumatology (OMERACT) US definitions: Achilles tendon, plantar fascia, proximal and distal patellar ligaments, and quadriceps tendon insertions. The findings then were correlated with the radiographic spinal abnormalities, Bath AS radiographic index (BASRI), Bath AS …

Authors

A Moshrif,MI Abdelkareem,S Rashad,A Negm,A Mosallam,H Bassiouni

Published Date

2022/6/1

AB1159 HYDROXYCHLOROQUINE SHORTAGE AND ITS RELATION TO ANXIETY LEVEL AND DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS DURING COVID-19 PANDEMIC

Background Concerns of hydroxychloroquine (HCQ) shortage for patients with rheumatic diseases are growing during the era of COVID-19 pandemic as it was assigned in some treatment protocols. Its nonavailability may impact the disease management especially in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).Objectives To evaluate the shortage of HCQ in patients with RA and SLE and its impact on patients anxiety and disease activity.Methods 219 RA patients (according to 2010 ACR/EULAR criteria) and 200 SLE patients (according to 2012 SLICC criteria) were recruited in the study. Demographic and clinical features of the patients together with the current disease activity parameters (CDAI and SELENA/SLEADI) were prospectively collected. previous disease activity measures were collected from the patients records before hydroxychloroquine shortage. Patient’s anxiety was …

Authors

MH Abu-Zaid,H Eitta,A Moshrif,D Abdeldaim,N EL Ghobashy

Published Date

2022/6/1

Computed tomography pulmonary angiography (CTPA) in Behçet’s disease patients: a remarkable gender gap and time to refine the treatment strategy

Objective The aim of the work was to delineate the computed tomography pulmonary angiography (CTPA) findings in Behçet’s disease (BD) patients with and without chest manifestations. Patients and methods The study included 122 BD adults recruited from 5 Teaching University Hospitals in Egypt of those who agreed to perform a CTPA. The Arabic version of BD current activity form (BDCAF) and BD damage index (BDI) were assessed. Detailed pulmonary manifestations, examination, plain radiology chest, and CTPA findings were recorded. Results The mean age of patients was 36.9 ± 11.3 years, male:female was 1.8:1, disease duration 9.6 ± 8.2 years, and age at onset 28.3 ± 8.6 years. Their mean BDCAF was 4.4 ± 2.2 and BDI 3.4 ± 1.8. There were chest manifestations in 51 (41.8%) and plain chest x-ray findings in …

Authors

Samar Tharwat,Suzan S ElAdle,Abdel Hafeez Moshrif,Faten Ismail,Rawhya El-Shereef,Esraa A Talaat,Sara Hassanein,Yousra Hisham,Tamer A Gheita,Egyptian College of Rheumatology (ECR) Behçet’s disease study groups

Journal

Clinical Rheumatology

Published Date

2022/1/1

Rheumatologists’ knowledge and perception of COVID-19 and related vaccines: the vaXurvey2 online survey

The study aimed to explore the experience of coronavirus disease-2019 (COVID-19) infection and vaccine adverse events (AEs) among rheumatologists. A validated questionnaire was distributed as a Google form to rheumatologists across the country via social networking sites from late December 2021 till early January 2022. The questionnaire included questions regarding participants' socio-demographic details, COVID-19 infection and vaccination details with special emphasis on AEs. Out of 246 responses, 228 were valid. 200 (81.3%) responders had received the vaccine. The mean age of the 228 participants was 37.9 ± 8.5 years, 196 were females and 32 males (F:M 6.1:1) from 18 governorates across the country. Comorbidities were present in 54 subjects (27%). There was a history of highly suspicious or confirmed COVID-19 infection in 66.7% that were all managed at home. The COVID-19 vaccine was …

Authors

Hanan M Fathi,Iman I El Gazzar,Mervat I Abd Elazeem,Enas AboulKheir,Nada M Gamal,Faten Ismail,Rawhya R El Shereef,Samar Tharwat,Shereen Elwan,Nermeen Samy,Noha Abdel Baki,Nora Y Elsaid,Amany S El-Bahnasawy,Abdelhfeez Moshrif,Yousra Abdel Fattah,Marwa A Amer,Maha E Ibrahim,Noha M Khalil,Soha El-Dessouki,Nouran Abaza,Amira T El-Shanawany,Eman F Mohamed,Nehal El-Ghobashy,Neveen Ayoub,Othman Hammam,Samar Fawzy,Safaa Sayed,Tamer A Gheita,Nevin Hammam,Egyptian College of Rheumatology (ECR) COVID-19 Study Group

Journal

Rheumatology International

Published Date

2022/6

OP0046 EVALUATION OF THE EFFICACY OF TOPICALLY APPLIED TACROLIMUS IN THE TREATMENT OF ORAL ULCERS IN BEHCET’S DISEASE: A DOUBLE BLIND PLACEBO CONTROLLED STUDY

Background Treatment of Behcet disease (BD) associating oral ulcers is still challenging despite the advances in the systemic treatment modalities.Objectives We aimed to evaluate the clinical efficacy of topical Tacrolimus for treatment of BD.Methods In this double blind placebo controlled trial, forty BD patients with persistent active oral ulceration were equally randomized into group I (20 patients received oral colchicine plus topically applied tacrolimus) and group II (20 patients received oral colchicine plus placebo oral gel). All participants were evaluated based on Behcet’s Disease Current Activity Form (BDCAF), Ulcer Severity Score (USS) and visual analog scale (VAS) before treatment, and at four-time points post-treatment (15 days, 1st, 2nd, and 3rd months).Results VAS was significantly lower in group I after 2 weeks (p= 0.037) and 3 months (0.025) than in group II. USS was significantly lower in group I after …

Authors

M Hassanien,A Moshrif,M Galal,F Abuzaid,D Fathalla,E Talaat

Published Date

2022/6/1

Evaluating gender differences in Egyptian fibromyalgia patients using the 1990, 2011, and 2016 ACR criteria

BackgroundFibromyalgia (FM) is a common rheumatic illness distinguished by chronic pain, fatigue, cognitive problems, and functional disability. However, the differences between men and women have not yet been comprehensively studied, especially after the development of the last 2016 American College of Rheumatology (ACR) criteria. The aim of this study was to evaluate the gender differences in symptom characteristics, cognitive dysfunction, and disease severity in Egyptian FM patients considering both the ACR 1990, 2011, and the last 2016 ACR diagnostic criteria.MethodsThis is a prospective cross-sectional study that was carried out on 352 patients with FM in the Rheumatology Department, Al-Azhar University Hospital in Egypt, in the period between January 1, 2020, and June 1, 2021. In addition to the number of tender points (TPC), data was collected on age, gender, body mass index (BMI), marital …

Authors

Abdelhfeez Moshrif,Mohamed Z Shoaeir,Awad Saad Abbas,Tarek M Abdel-Aziz,Wesam Gouda

Journal

Open Access Rheumatology: Research and Reviews

Published Date

2022/4/23

AB1212 GENDER DIFFERENCES IN FIBROMYALGIA PATIENTS IN VIEW OF THE 1990, 2011, AND 2016 ACR CRITERIA

Background Fibromyalgia (FM) is a common rheumatic illness distinguished by chronic pain, headache, fatigue, cognitive problems, and functional disability. However, the differences between men and women have not yet been comprehensively studied, especially after the development of the last 2016 American College of Rheumatology (ACR) criteria.Objectives The aim of this study was to evaluate the gender differences in symptom characteristics, cognitive dysfunction, and disease severity in Egyptian FM patients considering both the ACR 1990, 2011, and the last 2016 ACR diagnostic criteriaMethods In this cross-sectional study, 352 individuals with fibromyalgia were interviewed from January 1, 2020, to June 1, 2021. In addition to the number of tender points (TPC), data was collected on age, gender, body mass index (BMI), marital status, disease onset, duration, and diagnostic delay. The Widespread Pain …

Authors

A Moshrif,MZ Shoaeir,AS Abbas,TM Abdel-Aziz,W Gouda

Published Date

2022/6/1

Aging and entheses: An ultrasonographic probing of degenerative enthesopathy in a cohort of 147 healthy subjects

Aim To investigate the prevalence and features of degenerative enthesopathic changes in a large cohort of healthy individuals by musculoskeletal ultrasound (MSUS) and their relation to age and other demographic features. Methods In this cross‐sectional study, 147 healthy subjects (1470 entheses) were examined by MSUS according to the Outcome Measures in Rheumatology guidelines: Achilles tendon, plantar fascia, patellar, and quadriceps insertions of both lower limbs. Results The mean age (±SD) of the participants was 43.68 (±14.53) years and 57.1% were female. Enthesopathy has been detected in at least 1 area in 113 subjects (76.87%). Thickening (21.6%) and hypoechogenicity (15.3%) were the most frequent inflammatory findings while enthesophyte (10.13%) was the most prevalent structural one. Age and male gender were significantly correlating with inflammatory (rs = .341, P = .001/r = .310 …

Authors

Abdelhfeez Moshrif,Rasha Abdel Noor,Hany Aly,Mohamed Mortada,Ahmed Hafez

Journal

International Journal of Rheumatic Diseases

Published Date

2022/4

AB1231 ULTRASOUND-GUIDED INJECTION OF LOW MOLECULAR WEIGHT HYALURONIC ACID VERSUS STEROID FOR INFLAMMATORY AND DEGENERATIVE SACROILIITIS: A RANDOMIZED CONTROLLED TRIAL

Background Sacroiliitis may be degenerative (DSI) or inflammatory (ISI) and the latter is one of the clinical features of spondyloarthropathies.Objectives To determine the effect of hyaluronic acid versus corticosteroid injection for chronic sacroiliac joint arthropathy.Methods forty patients with sacroiliitis either degenerative (DSI: 20 patients) or inflammatory (ISI: 20 patients) based on the New York criteria. Each group was allocated into 2 subgroups; 10 patients received 2ml Betamethasone dipropionate plus 2 ml lidocaine 2% (A) and 10 patients received 2 ml hyaluronic acid plus 2 ml lidocaine 2% (B). All sacroiliac joint injections were done under ultrasonographic guidance using a 22-gauge needle. Visual analogue scale was used for pain assessment at base line, 1, 2 and 4 week post injection.Results there was no significant difference between main groups (ISI & DSI) regarding VAS score before injection, 1, 2 …

Authors

K Hosny,MI Abdelkareem,A Moshrif

Published Date

2022/6/1

Ultrasound-Guided Injection of Low Molecular Weight Hyaluronic Acid versus Steroid for Inflammatory and Degenerative Sacroiliitis: a Single-Blinded Randomized Controlled Trial

Background. Sacroiliitis may be degenerative (DSI) or inflammatory (ISI) and the latter is a clinical manifestation of spondyloarthropathies. Objective. To determine the effect of hyaluronic acid versus corticosteroid injection for chronic sacroiliac joint arthropathy.Methods. Forty patients with sacroiliitis either degenerative (DSI: 20 patients) or inflammatory (ISI: 20 patients) based on the New York criteria. Each group was allocated into 2 subgroups; 10 patients received 2 ml betamethasone dipropionate plus 2 ml lidocaine 2%(A) and 10 patients received 2 ml hyaluronic acid plus 2 ml lidocaine 2%(B). All sacroiliac joint injections were done under ultrasonographic guidance using a 22-gauge needle. Visual analogue scale (VAS) was used for pain assessment at base line, 1-, 2-and 4-week post injection.Results. No significant difference was observed between main groups (ISI and DSI) regarding VAS score before injection, 1-, 2-and 4-weeks post injection while a significant difference observed between subgroups A and B in ISI group at 2 and 4 weeks (p= 0.012 and 0.008, respectively). Also, there was a significant difference between subgroups A and B in DSI group at 1-, 2-and 4-weeks post injection (p= 0.04, 0.006 and 0.005, respectively). High significant difference before and after injection in the main groups and all subgroups was recorded. However, there was no significant difference between the subgroups of ISI and DSI. Conclusions. Both steroid and hyaluronic acid were effective in relieving pain in treatment of inflammatory and degenerative sacroiliitis, but steroid was more efficacious than the hyaluronic acid.Study registration. The trial …

Authors

M Abdelkreem,K Hussein,A Moshrif

Journal

Muscles, Ligaments and Tendons Journal

Published Date

2022

POS1292 ULTRASONOGRAPHIC GUIDED INTRA ARTICULAR STEROID AND HYALURONIC ACID IN ADHESIVE CAPSULITIS WITH AND WITHOUT SUPRASCAPULAR NERVE BLOCK

Background Adhesive capsulitis (AC), often known as frozen shoulder, is a common musculoskeletal condition characterised by shoulder pain and reduced active and passive mobility. Intra-articular injections is an effective treatment option and provide faster pain relief in patients with ACObjectives Compare the effictiveness of intra articular injection (IAI) of steroid and HA with or without Suprascapular nerve block (SSNB) in the management of AC.Methods Randomized control trial involved 80 patients (62 women and 18 men) clinically diagnosed as having adhesive capsulitis divided into 2 main groups; intra articular injection with SSNB (40 cases) and without SSNB (40 cases), each group divided into 2 subgroups; Twenty patients were treated with ultrasound guided intra articular injection of steroid (4ml of 2% lidocaine and 2 ml of 40 mg/ml triamcinolone) and another twenty patients were treated with …

Authors

E Mohamed,A Metwaly,A Moshrif,M Elwan

Published Date

2022/6/1

Hydroxychloroquine non-availability during COVID-19 pandemic and its relation to anxiety level and disease activity in rheumatoid arthritis and lupus patients: a cross …

BackgroundDuring COVID-19 disease era, there is an accelerated demand for hydroxychloroquine since it was suggested by some centers as potential therapy for COVID-19 which has led to diminished supplies for patients with rheumatic disease and which carried unexpected risk for disease flare particularly in patients with systemic lupus erythematosus and rheumatoid arthritis. The purpose of the work is to detect the effect of HCQ shortage in patients with RA and SLE on anxiety and disease activity.ResultsA total of 320 patients were divided into two groups: group 1—216RA patients with mean age 45.5 ± 9.59 years, disease duration 43.4 ± 25.6 months with female predominance (62.5%). Group 2—104 SLE patients with mean33.4 ± 7.9 age years, disease duration 52.1 ± 34.6 months with female predominance (85.6%). HCQ shortage occurred in 174 RA patients (80.5%) and 76 lupus patients (73.1%). Despite …

Authors

Mohammed Hassan Abu-Zaid,Hany M Aly,Abdelhafeez Moshrif,Doaa E Abdeldaim,Nehal El-Ghobashy

Journal

Egyptian Rheumatology and Rehabilitation

Published Date

2022/12

Ultrasonographic Guided Intra Articular Steroid versus Hyaluroni c Acid in Adhesive Capsulitis with and without Suprascapula r Nerve Block: a Randomized Controlled Trial

Objective. To compare the effictiveness of intra articular injection (IAI) of steroid and HA with or without Suprascapular nerve block (SSNB) in the management of AC. Patients and methods. Randomized controlled trial involved 80 patients (62 women and 18 men) clinically diagnosed as having adhesive capsulitis divided into 2 main groups: intra articular injection with SSNB (40 cases) and without SSNB (40 cases), each group divided into 2 subgroups. Twenty patients were treated with ultrasound guided intra articular injection of steroid (4 ml of 2% lidocaine and 2 ml of 40 mg/ml triamcinolone) and another twenty patients were treated with ultrasound guided intra articular injection of hyaluronic acid (4 ml of 2% lidocaine and 2 ml hyaluronic acid). Results. Intra articular shoulder injection with SSNB has higher significant visual analogue scale (VAS) score at baseline and lower significant VAS score at 1st and 3rd week (p< 0.001). However, there was no significance between both groups regarding disability score at 3rd week (p= 0.316). In contrast, there was a high significance between them considering disability score at baseline, 1st, 6th week (p< 0.001 and 0.008, respectively).Conclusions. In patients with adhesive capsulitis, both a combination an IAI alone or with SSNB dramatically improved pain and functional results. The use of an SSNB in conjunction with an IAI especially with steroid enhanced therapeutic effectiveness. Study registration. Our study achieved retrospectively the pan African clinical trial registry acceptance No. PACTRA202111695655746.

Authors

M Elwan Sayed,E Mohammed Hussein,A Moslaem Ebrahim,A Moshrif

Journal

Muscles, Ligaments and Tendons Journal

Published Date

2022

knowledge, attitude and misconceptions about osteoporosis among patients with musculoskeletal health problems

Purpose/Introduction: To determine the level of awareness and knowledge about osteoporosis among a sample of patients with musculoskeletal diseases.Methods: Through a cross-sectional study on patients with musculoskeletal disorders either degenerative or inflammatory (aged 18-62 years), 1200 participants were interviewed and responded to a prepared validated questionnaire about the knowledge and attitude towards Osteoporosis (OP) and its potential complications as fragility fractures and kyphosis.Results: Seventy eight percent (936) of the studied subjects know osteoporosis (of them only 930 agreed to complete the study) while 22% did not know a disease called osteoporosis and did not complete the remaining questions. A positive effect was found for educational level, occupation, and residence on knowledge of osteoporosis (P= 0.000, P= 0.001, P= 00.002 respectively). Among those who completed the questionnaire, the majority (72.2% and 82%) were found to have the misconceptions that OP can lead to joint deformities and bone pain which reflected that their knowledge about the disease lacks the required in-depth awareness.Conclusion: There are variable degrees of knowledge and attitudes towards osteoporosis among patients with musculoskeletal disorders which are affected by multiple factors including educational level, occupation, residence and marital status. However, the in-depth awareness about the disease is highly limited and efforts should be done to overcome this point as a first step to prevent the disease.

Authors

H. Khalifa A Moshrif,H Ali

Journal

international journal of clinical rheumatology

Published Date

2021

The effect of Helicobacter pylori seropositivity and activity on disease outcome in patients with rheumatoid arthritis, systemic lupus erythematosus and ankylosing spondylitis

The association between infection with Gram-negative bacteria and autoimmune diseases has been investigated with controversies about the role of the organisms especially, Helicobacter pylori (H. pylori). To evaluate the impact of the presence and activity of H. pylori on the disease activity in patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and ankylosing spondylitis (AS). This study was carried out on one hundred adult patients and 50 controls. Patients included 40 RA, 40 SLE, and 20 AS. Participants were subjected to clinical examination and laboratory investigations; ESR (spectrophotometric assay), CRP (turbidimetric method), serum H. pylori IgG antibody test (enzyme immunoassay), and H. pylori antigen test (lateral flow immunoassay, rapid onestep test) in stool. Positive test in stool indicated active current H. pylori infection. Mean age of patients was 36.95±10.34; 51.2±6.91, 35.5±3.71, and 48.82±5.81 in SLE, RA, AS, and control groups respectively. Serum H. pylori IgG antibodies was 0.803±0.497 U/mL in SLE group, 1.48±0.637 U/mL in RA group and 0.75±0.68 U/mL in AS group while it was 0.2±0.61 U/mL in the control group with a significant difference (P= 0.000). The H. pylori antigen in stool was found positive in 30%, 70% and 20% of patients of the three groups respectively while it was positive in 10% of the control group with P> 0.001. Patients with active SLE (SLEDAI> 3) and RA (DAS-28> 3.2) demonstrated higher frequency of positive test for H. pylori antigen in stool than patients at remission (66.7% P= 0.02 and 83.3% P= 0.01 respectively). In contrast, 22.2% of patients with active AS (BASDAI> 4 …

Authors

Asmaa E Hamed,Abdelhfeez Moshrif,Mohamed Ryan,Mona M Abdelmaguid,Haitham A Azeem,Mohamed I Abdelkreem

Journal

Egypt J Immunol

Published Date

2021/10/1

Macrophage activation syndrome triggered by systemic lupus erythematosus flare: successful treatment with a combination of dexamethasone sodium phosphate, intravenous …

Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s disease and systemic juvenile idiopathic arthritis. Macrophage activation syndrome is less commonly detected in adult patients with systemic lupus erythematosus, which, if untreated, can be fatal, though determining the optimum treatment strategy is still a challenge. Case presentation Herein, we report a case of macrophage activation syndrome in a 33-year-old Egyptian female as an unusual complication of a systemic lupus erythematosus flare in adult patients. Our patient was initially treated with a combination of intravenous methylprednisolone pulse therapy and intravenous immunoglobulin therapy …

Authors

Wesam Gouda,Faisal Alsaqabi,Abdelhfeez Moshrif,Md Asiful Islam

Journal

Journal of Medical Case Reports

Published Date

2021/10/7

Rheumatology university faculty opinion on coronavirus disease-19 (COVID-19) vaccines: the vaXurvey study from Egypt

Objectives The aim of the present work was to explore the perspectives of Egyptian Rheumatology staff members as regards the coronavirus disease-19 (COVID-19) vaccine. Methods The survey is composed of 25 questions. Some questions were adapted from the global rheumatology alliance COVID-19 survey for patients. Results 187 rheumatology staff members across Egypt from 18 universities and authorizations actively participated with a valid response. The mean time needed to complete the survey was 17.7 ± 13 min. Participants were 159 (85%) females (F:M 5.7:1). One-third agreed that they will be vaccinated once available, 24.6% have already received at least one dose, 29.4% are unsure while 16% will not take it. Furthermore, 70.1% agreed that they will recommend it to the rheumatic diseases (RD …

Authors

Nevin Hammam,Samar Tharwat,Rawhya R El Shereef,Ahmed M Elsaman,Noha M Khalil,Hanan M Fathi,Mohamed N Salem,Hanan M El-Saadany,Nermeen Samy,Amany S El-Bahnasawy,Yousra H Abdel-Fattah,Marwa A Amer,Emad ElShebini,Amira T El-Shanawany,Dina H El-Hammady,Rasha Abdel Noor,Marwa ElKhalifa,Faten Ismail,Rasha M Fawzy,Amany R El-Najjar,Zahraa I Selim,Nouran M Abaza,Ahmed R Radwan,Mervat IAbd Elazeem,Wael Abdel Mohsen,Abdel Hafeez Moshrif,Eman F Mohamed,Loay I Aglan,Soha Senara,Maha E Ibrahim,Iman Khalifa,Rasha El Owaidy,Noha El Fakharany,Reem Hamdy A Mohammed,Tamer A Gheita,Egyptian College of Rheumatology (ECR) COVID-19 Study Group

Journal

Rheumatology International

Published Date

2021/9

Development and validation of a Behçet's Disease Damage Index for adults with BD: An Explicit, Composite and Rated (ECR) tool

Background Behçet's disease (BD) is a chronic multisystem variable vessel vasculitis. Disease damage is irreversible and permanent. Validated tools evaluating damage are limited. Enhancements in the clinical treatment of vasculitis will take place from the development of refined and exclusive indices for individual vasculitic syndromes including BD and attempting their international validation. Objectives This aim was to develop and validate a simple BD Damage Index (BDI). Methods This was a nationwide study including 1252 BD patients. The work consisted of 3 stages. Stage 1: items generation for score content. Stage 2: items selection for the draft score was performed by an expert rheumatologist. Stage 3: the content validity of the draft score was assessed and BDI, Vasculitis Damage Index (VDI), Antineutrophil cytoplasmic antibody‐associated Vasculitis Index of Damage (AVID) and Combined Damage …

Authors

Tamer A Gheita,Nevin Hammam,Samar M Fawzy,Eiman Abd El‐Latif,Iman I El‐Gazzar,Nermeen Samy,Dina H El‐Hammady,Rasha Abdel Noor,Emad El‐Shebini,Amany R El‐Najjar,Nahla N Eesa,Mohamed N Salem,Soha E Ibrahim,Dina F El‐Essawi,Ahmed M Elsaman,Soha Senara,Hanan M Fathi,Rehab A Sallam,Rawhya R El Shereef,Mervat I Abd Elazeem,Rasha M Fawzy,Noha M Khalil,Dina Shahin,Hanan M El‐Saadany,Marwa ElKhalifa,Samah I Nasef,Ahmed M Abdalla,Nermeen Noshy,Emtethal A Said,Ehab Saad,Abdel Hafeez Moshrif,Amira T El‐Shanawany,Yousra H Abdel‐Fattah,Hala A Raafat,Hossam M Khalil,Egyptian College of Rheumatology‐Behçet's Disease Study Group (ECR‐BDSG)

Journal

International Journal of Rheumatic Diseases

Published Date

2021/8

Éléments d’enthésopathie chez les individus sains et leurs relations avec les caractéristiques démographiques: une étude échographique de 147 volontaires

Introduction/ObjectifsÉvaluer la prévalence et la distribution de l’enthésopathie chez les individus sains par échographie (US) et leur relation avec les caractéristiques démographiques.Matériels et méthodesDans cette étude transversale, 147 sujets (1470 enthèses) ont été examinés par échographie selon les critères de jugement des directives de rhumatologie (OMERACT) ; tendon d’Achille, fascia plantaire, insertions rotulienne et quadriceps des deux membres inférieurs. Les résultats ont été corrélés avec les caractéristiques démographiques.RésultatsL’âge moyen (± ET) des participants était de 43,68 (± 14,53) ans et 57,1 % étaient des femmes. L’enthésopathie a été détectée dans au moins une zone chez 113 sujets (76,87 %). L’épaississement (21,6 %) et l’hypoéchogénicité (15,3 %) étaient les signes inflammatoires les plus fréquents, tandis que l’ enthésophyte (10,13 %) était le signe structurel le plus …

Authors

A Moshrif,A Rasha,H Ali,M Mortada,A Hafez

Journal

Revue du Rhumatisme

Published Date

2021/12/1

Adult systemic lupus erythematosus in Egypt: The nation-wide spectrum of 3661 patients and world-wide standpoint

ObjectiveThe aim of this study was to present the epidemiology, clinical manifestations and treatment pattern of systemic lupus erythematosus (SLE) in Egyptian patients over the country and compare the findings to large cohorts worldwide. Objectives were extended to focus on the age at onset and gender driven influence on the disease characteristics.Patients and methodThis population-based, multicenter, cross-sectional study included 3661 adult SLE patients from Egyptian rheumatology departments across the nation. Demographic, clinical, and therapeutic data were assessed for all patients.ResultsThe study included 3661 patients; 3296 females and 365 males (9.03:1) and the median age was 30 years (17–79 years), disease duration 4 years (0–75 years) while the median age at disease onset was 25 years (4–75 years). The overall estimated prevalence of adult SLE in Egypt was 6.1/100,000 population (1 …

Authors

Tamer A Gheita,Rasha Abdel Noor,Esam Abualfadl,Osama S Abousehly,Iman I El-Gazzar,Rawhya R El Shereef,Soha Senara,Ahmed M Abdalla,Noha M Khalil,Ahmed M ElSaman,Samar Tharwat,Samah I Nasef,Eman F Mohamed,Nermeen Noshy,Dina F El-Essawi,Abdel Hafeez Moshrif,Rasha M Fawzy,Amany R El-Najjar,Nevin Hammam,Faten Ismail,Marwa ElKhalifa,Nermeen Samy,Eman Hassan,Nouran M Abaza,Emad ElShebini,Hanan M Fathi,Mohamed N Salem,Yousra H Abdel-Fattah,Ehab Saad,Mervat I Abd Elazim,Nahla N Eesa,Amany S El-Bahnasawy,Dina H El-Hammady,Amira T El-Shanawany,Soha E Ibrahim,Emtethal A Said,Hanan M El-Saadany,Zahraa I Selim,Samar M Fawzy,Hala A Raafat

Journal

Lupus

Published Date

2021/8

Systemic lupus erythematosus children in Egypt: Homeland spectrum amid the global situation

ObjectivesThis study aims to present the manifestations of juvenile systemic lupus erythematosus (JSLE) across Egypt, to focus on age at onset and gender-driven influence on disease characteristics, and to compare findings to other countries.MethodsThe study included 404 Egyptian children with systemic lupus erythematosus (SLE) presenting to one of the specialized rheumatology centers corresponding to 13 major governorates. Juvenile cases age was ≤ 16°years at the time of recruitment. The SLE Disease Activity Index (SLEDAI) and damage index (DI) were assessed.ResultsThe mean age was 13.2 ± 2.4°years; 355 females and 49 males (7.2:1), and the disease duration was 2.3 ± 1.6 years, while age at disease onset was 11.1 ± 2.5°years. Their SLEDAI was 13.5 ± 12.3, and DI, 0.36 ± 0.78. The overall estimated prevalence of childhood-SLE patients in the recruited cohort in Egypt was 1/100,000 …

Authors

Nahla N Eesa,Hend Abdel Nabi,Rasha El Owaidy,Iman Khalifa,Ahmed R Radwan,Abeer M NourEl-Din,Marwa A Amer,Rawhya R ElShereef,Eman Hassan,Faten Ismail,Iman I El-Gazzar,Noha M Khalil,Abdel Hafeez Moshrif,Esam Abualfadl,Samar Tharwat,Hanan M Fathi,Mervat I Abd Elazeem,Emad El-Shebini,Nermeen Samy,Nermeen Noshy,Amany S El-Bahnasawy,Ahmed M Abdalla,Osama S Abousehly,Eman F Mohamed,Samah I Nasef,Ahmed M Elsaman,Marwa ElKhalifa,Mohamed N Salem,Nouran M Abaza,Hanan M Fathy,Nancy Abdel Salam,Hanan M El-Saadany,Amany R El-Najjar,Dina H El-Hammady,Nevin Hammam,Reem HA Mohammed,Tamer A Gheita,Egyptian College of Rheumatology (ECR) SLE Study Group

Journal

Lupus

Published Date

2021/11

Impact of COVID-19 pandemic on rheumatoid arthritis from a Multi-Centre patient-reported questionnaire survey: influence of gender, rural–urban gap and north–south gradient

During the coronavirus disease-2019 (COVID-19) pandemic there were several barriers to treatment access and medication adherence in rheumatoid arthritis (RA) patients. There is no information regarding the RA patient health status in Egypt during the COVID-19. Thus,the aim of this work was to study the impact of the pandemic on RA patients through a patient-reported questionnaire and to determine the influence of gender, geographic regions. This multi-centre study initiated by the Egyptian College of Rheumatology (ECR) was conducted on 1037 RA patients attending rheumatology clinics from 10 governorates. The questionnaire provided covered socio-demographic data, health/disease status, information/knowledge about COVID-19 and medical/family history of the infection. Patients mean age was 44.2 ± 12.3 years;855 females and 182 males; 539(52%) from rural and 497(48%) from urban …

Authors

Esam Abualfadl,Faten Ismail,Rawhya R El Shereef,Eman Hassan,Samar Tharwat,Eman F Mohamed,Essam A Abda,Ahmed R Radwan,Rasha M Fawzy,Abdel Hafeez Moshrif,Rasha Abdel Noor,Soha Senara,Mervat I Abd Elazim,Nouran M Abaza,Hala A Raafat,Iman I El-Gazzar,Dina H El-Hammady,Nevin Hammam,Tamer A Gheita,Reem El-Mallah,ECR COVID19-Study Group

Journal

Rheumatology international

Published Date

2021/2

Development of an Arabic version of the Behçet’s Disease Current Activity Form (Ar-BDCAF): cross-cultural adaptation and validation initiative in Egypt

BackgroundBehçet’s disease (BD), commonly seen in the Silk road countries, is a variable vessel vasculitis with no specific investigation that reflects disease activity. The Behçet’s Disease Current Activity Form (BDCAF) is the most famous and acceptable clinical activity score.PurposeTo develop a cross-cultural adaptation of the BDCAF to the Arabic language (Ar-BDCAF)—Egyptian dialect—across the country and to consider preliminary evaluation of its reliability in assessment of BD activity.Patients and methodsThe score was translated to Arabic language and revised by 3 rheumatology consultants. Reliability of Ar-BDCAF was tested among 88 BD patients from 9 Egyptian main city centers. Patients were questioned by two specialists at 30 min interval to evaluate inter-observer rating and twice by the same physician within 24 h to assess the intra-observer rating.ResultsPatients were 64 males and 24 females (2 …

Authors

Tamer A Gheita,Hanan M Fathi,Nahla N Eesa,Emad El-Shebini,Samar Tharwat,Nevin Hammam,Rasha M Fawzy,Rawhya R El-Shereef,Mona H Abd El-Samea,Rasha A Abdel Noor,Mohamed N Salem

Journal

Clinical Rheumatology

Published Date

2021/11

AB0956 VERTICAL NAIL RIDGING IN PATIENTS WITH FIBROMYALGIA: FREQUENCY, PROPOSED GRADING AND CORRELATION WITH OTHER DISEASE FEATURES

Background The vertical nail ridging (VNR) has long been reported to be related to stressful conditions1Objectives to evaluate the frequency of VNS in FM patients and its relation to other disease parameters depending on a proposed grading.Methods VNR has been searched for in 212 FM patients (2016 criteria). The number of fingers, the degree of VNR according to this proposed grading (0: no ridging, 1: ridging only detected by a magnifying lens, 2: ridging seen by naked eye and 3: ridging that can be seen and felt) and other FM features according to the new and old ACR criteria have been recorded. 80 subjects of those consulting for knee osteoarthritis have been examined for VNR and those found positive were asked about the FM features and examined for tender points. Patients aged >50 years and those with psoriasis and fungal infections were excluded.Results the mean age of patients was 32.4±9.9 (73 …

Authors

A Moshrif,M Abdelkareem,M Moneer,A Mosallam,A Ismail,M Elwan,A Saad,T Abdelaziz

Published Date

2020/6/1

THU0466 Early diagnosis is associated with less disease severity and better outcome in fibromyalgia syndrome: a tricentric prospective analysis of a cohort of 370 patients

Background Delayed diagnosis of fibromyalgia (FM) has been reported to be associated with more economic burden, healthcare utilization and worse response to treatment1,2. However, its impact on the patients’ symptomatology and disease severity is still underestimated.Objectives to evaluate the effect of diagnostic delay (DD) on FM severity and disease assessment parameters.Methods in this cross sectional study, 370 FM patients were prospectively interviewed. Information about DD, widespread pain index (WPI), symptom severity scale (SSS), total severity scale (SSS+WPI) and number of tender points were collected. We proposed to classify our patients into 3 categories; early diagnosis (ED ≤ 2 years; 83 patients), late diagnosis (LD: >2-7 years; 198) and very late diagnosis (VLD >7 years; 89 patients).Results the mean age of patients was 33.9 (±9.8) and 79.4 % were female. The mean for DD was 5.6 (±3 …

Authors

A Moshrif,W Gouda,MH Abu-Zaid

Published Date

2020/6/1

Subclinical hepatitis C virus infection in Egyptian patients with rheumatic diseases: a multi-center study

Background Hepatitis C virus (HCV) infection is highly prevalent in Egypt. It was found to be 7.0% in a study done in 2015. There are some studies on the prevalence of HCV in rheumatoid arthritis, but to our knowledge, no previous study was done to detect it in other rheumatologic diseases. This study aims at detecting the prevalence of subclinical HCV infection in Egyptian patients with different rheumatic diseases. In the current study, eight hundred and three patients with different rheumatic diseases collected from five—geographically different—Egyptian rheumatology departments were studied. Patients with known current or previous HCV infection were excluded from the study. Screening for the positive anti-HCV antibodies was done for all patients. Screening for the presence of HCV ribonucleic acid (RNA) was done in patients with positive serology by reverse transcriptase-polymerase chain reaction …

Authors

Safaa Ali Mahran,Alaa AA Mohamed,Dalia A Nigm,MZA Abu Rahma,S Abd-Elsalam,Hesham Hamoud,M Hamdy,MI Risha,Ahmad Hamdy,Mohamed M Abdelkareem,Saad Ghanem,Mohamed Hanafy,Abdelhafeez Moshrif,A Fehr,Fatma H ElNouby,A Osman,Manal M Hassanien

Journal

Egyptian Rheumatology and Rehabilitation

Published Date

2020/12

Ischemic stroke as the first presentation of takayasu’s arteritis in young male

Takayasu's arteritis should be kept under the differential diagnosis of stroke in all young patients. Early, proper diagnosis and treatment are necessary to reduce any further progression, morbidity, and mortality rates of the disease.

Authors

Wesam Gouda,Faisal Alsaqabi,Amjad Alkadi,Hanan Abd El‐Aziz Amr,Abdelhafeez Moshrif,Mohammed E Mahdy

Journal

Clinical Case Reports

Published Date

2020/2

Deep friction massage versus local steroid injection for treatment of plantar fasciitis: a randomized controlled trial

Background Deep friction massage (DFM) has long been proven to be effective in treatment of some tendinopathies. The aim of our study was to evaluate the efficacy of this physical modality in the treatment of plantar fasciitis in comparison with local steroid injection. Results Sixty patients were assigned into 2 groups through a computer-based randomization table and completed the treatment and follow-up assessments; thirty in group I received 40 mg local triamcinolone injection and thirty in group II received 7 sessions of DFM. Demographic data showed a statistically insignificant difference in age, female to male ratio, and body mass index (BMI) in both groups. The mean for age was 39.42 years in group I and 41.32 years in group II (P = 0.86); the female to male ratio was 3:1 in group I and 2.75:1 in group II, and the mean for BMI was 32.41 in group I and 33.31 in group II (P = 0.51). At 2 and 6 weeks …

Authors

Abdelhfeez Moshrif,Mohamed Elwan,Osama S Daifullah

Journal

Egyptian Rheumatology and Rehabilitation

Published Date

2020/12

Rheumatologists’ practice during the Coronavirus disease 2019 (COVID-19) pandemic: a survey in Egypt

The aim of this work is to trace how rheumatologists all over Egypt are approaching the COVID-19 pandemic and what changes it has brought about in the patients’ care with special attention to its effect on vulnerable rheumatic disease (RD) patients. This survey further aims to help inform the rheumatology community about the changes in practice during the COVID-19 pandemic. The survey included 26 questions distributed to University staff members across Egypt members of the Egyptian College of Rheumatology (ECR). It takes 5–10 min to fill out. The practice setting of participating rheumatologists included University Teaching Hospitals that are the main rheumatology and clinical immunology service providers for adults and children RD patients. There was an overall agreement across the country in the responses to the survey that took a median time of 7 min to fill in. Potential changes in rheumatology …

Authors

Tamer A Gheita,Mohamed N Salem,Nahla N Eesa,Noha M Khalil,Nada M Gamal,Rasha Abdel Noor,Abdel Hafeez Moshrif,Rawhya El Shereef,Faten Ismail,Nermeen Noshy,Rasha M Fawzy,Emad Elshebini,Iman Khalifa,Hanan El Saadany,Samar Tharwat,Amany El-Najjar,Yousra Abdel Fattah,Rehab Sallam,Amany S El-Bahnasawy,Ola Gharbia,Eman Hassan,Amira ElShanawany,Eman F Mohamed,Soha Senara,Mervat Ismail,Samah I Nasef,Ahmed M Abdalla,Dina Elessawi,Samar M Fawzy,Esam Abu Alfadl,Asmaa Khalifa,Nouran M Abaza,ECR COVID19-Study Group

Journal

Rheumatology International

Published Date

2020/10

THU0490 DEEP FRICTION MASSAGE VERSUS LOCAL STEROID INJECTION FOR TREATMENT OF PLANTAR FASCIITIS: A RANDOMIZED CONTROLLED TRIAL

Background Deep friction massage (DFM) has long been proven to be effective in the treatment of some tendinopathies.Objectives to evaluate the efficacy of DFM in the treatment of plantar fasciitis (PF) in comparison with local steroid injection.Methods In this randomized controlled trial, 60 patients with PF were selected from those attending the rheumatology and rehabilitation outpatient clinic and then randomized to receive either 40 mg triamcinolone local injection (group I: 30 patients; 41 heals) using the medial approach or to receive seven sessions of deep transverse friction massage (10 min each) every other day (group II: 30 patients; 36 heels). The outcome measures were the pain and function assessment by visual analog scale and foot function index, respectively, at 2 and 6 weeks of follow-up.Results Demographic data showed a statistically insignificant difference in age, female to male ratio, and BMI in …

Authors

A Moshrif,M Elwan,U Daifallah

Published Date

2020/6/1

See List of Professors in Abdelhafeez Moshrif University(Al-Azhar University)

Abdelhafeez Moshrif FAQs

What is Abdelhafeez Moshrif's h-index at Al-Azhar University?

The h-index of Abdelhafeez Moshrif has been 10 since 2020 and 10 in total.

What are Abdelhafeez Moshrif's top articles?

The articles with the titles of

Clinical implications of seropositive and seronegative autoantibody status in rheumatoid arthritis patients: A comparative multicentre observational study

Clinical and ultrasonogrpahic evaluation of efficacy and safety of intralesional injection of autologous platelet-rich plasma in morphea: A comparative case series

Evaluating the Effect of Delayed Diagnosis on Disease Outcome in Fibromyalgia: A Multi-Center Cross-Sectional Study

POS1347 EVALUATING THE EFFICACY OF LOCAL CORTICOSTEROID INJECTION, PLATELET-RICH PLASMA, AND EXTRACORPOREAL SHOCKWAVE THERAPY IN PATIENTS WITH PES ANSERINE BURSITIS: A PILOT …

Ultrasound abnormalities of the major salivary glands in Egyptian patients with systemic sclerosis

Efficacy of Autologous Platelet Rich Plasma on Morphea: A Comparative Clinical and Ultrasonographic Follow-up Study

Comparing the Efficacy of Local Corticosteroid Injection, Platelet-Rich Plasma, and Extracorporeal Shockwave Therapy in the Treatment of Pes Anserine Bursitis: A Prospective …

Rheumatoid arthritis study of the Egyptian College of Rheumatology (ECR): nationwide presentation and worldwide stance

...

are the top articles of Abdelhafeez Moshrif at Al-Azhar University.

What are Abdelhafeez Moshrif's research interests?

The research interests of Abdelhafeez Moshrif are: Rheumatology

What is Abdelhafeez Moshrif's total number of citations?

Abdelhafeez Moshrif has 394 citations in total.

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