Abdelfattah M selim

Abdelfattah M selim

Benha University

H-index: 26

Africa-Egypt

Professor Information

University

Benha University

Position

Assistant professor of infectious disease Faculty of Veterinary Medicine

Citations(all)

1677

Citations(since 2020)

1580

Cited By

375

hIndex(all)

26

hIndex(since 2020)

25

i10Index(all)

50

i10Index(since 2020)

50

Email

University Profile Page

Benha University

Research & Interests List

Infectious disease of animal

Bacteriology

Molecular biology

Top articles of Abdelfattah M selim

Molecular Characterization of Pasterulla Multocida in Fattening Bovine

Pasteurella multocida infection has serious complications for both human and animal health. In bovines, it is the predominant cause of fatal pneumonia, with a mortality rate up to 100%, especially in severe undiagnosed cases. Therefore, this study was conducted for molecular identification and characterization of P. multocida in nasal swabs and pneumonic lung tissue in cattle calves less than one year  suffered from pneumonia  and respiratory disorders.  The detection of P. multocida was higher in pneumonic lung tissue (40%) than in nasal swabs. Only 37 out of 109 collected samples were positive for P. multocida using bacteriological culture and those samples were confirmed by PCR targeting Kmt1 gene. The phylogenetic analysis of local P. multocida isolate revealed close relation with other P. multocida strains from bovine from Egypt, China, USA and Canada. Consequently, establishing a potent epidemiological surveillance program is necessary to decrease the spreading of disease and the economic losses among fattening calves.

Authors

Ahmed Radwan,Islam Zakria,Rania AboSakya,Faysal Arnaout,Abdelfattah Selim

Journal

Egyptian Journal of Veterinary Sciences

Published Date

2025/2/1

Nanostructure Lipid Carrier of Curcumin Co-Delivered with Linalool and Geraniol Monoterpenes as Acetylcholinesterase Inhibitor of Culex pipiens

(1) Background: A molecular hybridization docking approach was employed to develop and detect a new category of naturally activated compounds against Culex pipiens as acetylcholinesterase inhibitors via designing a one-pot multicomponent nano-delivery system. (2) Methods: A nanostructure lipid carrier (NLC), as a second generation of solid lipid nanoparticles, was used as a carrier to deliver the active components of curcumin (Cur), geraniol (G), and linalool (L) in one nanoformulation after studying their applicability in replacing the co-crystallized ligand imidacloprid. (3) Results: The prepared nanostructure showed spherical-shaped, polydisperse particles ranging in size from 50 nm to 300 nm, as found using a transmission electron microscope. Additionally, dynamic light scattering confirmed an average size of 169 nm and a highly stable dispersed solution, as indicated by the zeta potential (−38 mV). The prepared NLC-Cur-LG displayed competitive, high-malignancy insecticidal activity against fourth instar C. pipiens with an elevated rate of death of 0.649 µg/mL. The treatment, due to the prepared nanostructure, affects oxidative stress enzymes, e.g., hydrogen peroxide (4 ppm), superoxide dismutase (SOD) (0.03 OD/mg), and protein carbonyl (0.08 OD/mg), and there are observable upward and downward fluctuations when using different concentrations of NLC-Cur-LG, suggesting significant problems in its foreseeable insecticidal activity. The acetylcholinesterase activity was assessed by an enzyme inhibition assay, and strengthened inhibition occurred due to the encapsulated NLCs (IC50 = 1.95 µg/mL). An investigation of the gene …

Authors

Ibrahim Taha Radwan,Nirvina Abdel Raouf Ghazawy,Abeer Mousa Alkhaibari,Hattan S Gattan,Mohammed H Alruhaili,Abdelfattah Selim,Mostafa E Salem,Eman Alaaeldin AbdelFattah,Heba M Hamama

Journal

Molecules

Published Date

2024/1/4

Acaricidal Efficacy of Thirty-Five Egyptian Plants Against the Camel Tick, Hyalomma Dromedarii

PurposeAlternative and affordable tick control strategies are crucial to control and prevent tick bites and tick-borne diseases.MethodsIn this study, we evaluated the acaricidal efficacy of 35 aqueous plant extracts (17%) against the camel tick, Hyalomma dromedarii.ResultsThe phytochemical profile indicated the presence of various secondary substances. Plants were classified into three groups according to their mortality percentage 15 days post-treatment with 17%. This highly effective group (91%–95%) comprised Ocimum basilicum, Mespilus germanica, and Viola alpine followed by Carum carvi, Cucurbita pepo (peel), and Peganum harmala. A moderately effective group (80%–90%) included Acacia nilotica, Apium graveolens, Capsicum annuum, Ceratonia siliqua, Cucurbita pepo (seeds), Equisetum arvense, Eruca sativa, Ginkgo biloba, Plantago psyllium, Phyllanthus emblica, Punica granatum, and Ziziphus …

Authors

Hanem F Khater,Eman KA Bazh,Samah Abdel Gawad,Abdelfattah Selim,Hanan AA Taie,Ibrahim T Radwan,Shawky A Moustafa,Ameer A Megahed,Mohamed M Baz,Sahar A Kandeel

Journal

Acta Parasitologica

Published Date

2024/4/26

Seroprevalence and associated risk factors for bovine leptospirosis in Egypt

Leptospirosis is caused by pathogenic bacteria of the genus Leptospira and is one of causative agents of reproductive problems leading to negative economic impact on bovine worldwide. The goal of this study was to investigate the seroprevalence of Leptospira spp. in cattle in some governorates of Egypt's Nile Delta and assess the risk factors for infection. A total of 410 serum samples were collected from cattle and examined using microscopic agglutination test. The overall seroprevalence was 10.2% and the most prevalent serovars were Icterohaemorrhagiae, Pomona and Canicola. In addition, the potential risk factors were associated Leptospira spp. infection were age, herd size, history of abortion, presence of dogs and rodent control. Thus, leptospirosis is common in dairy cattle in the Nile Delta and  the presence of rodents in feed and dog-accessible pastures increases the risk of Leptospira spp. infection …

Authors

Abdelfattah Selim,Mohamed Marzok,Hattan S Gattan,Abdelhamed Abdelhady,Mohamed Salem,Abdelrahman M Hereba

Journal

Scientific Reports

Published Date

2024/2/26

Seroprevalence and Assessment of Risk Factors Associated to Borrelia burgdorferi Infection in Egyptian Horses

Q fever or Coxiellosis is a worldwide zoonotic bacterial disease caused by Coxiella burnetii organism. Coxiellosis incriminated in a pronounced economic impact on the veterinary industry, along with presenting serious public health hazards among human. This current study was conducted during the period from October 2022 to December 2023 to assess the seroprevalence and the possible risk factors associated with C. burnetii infection in cattle in Toukh, Qalubyia governorate. The historical background of cattle under investigation indicated contact with small ruminants, and occurrences of reproductive disorder as abortions and stillbirths. Moreover, clinical investigation of animals revealed presence of tick infestation. A commercial ELISA kit (IDEXX) was utilized in the current study and the recorded overall seroprevalence rate of C. burnetii infection was 47%. Moreover, the statistical analysis also revealed that Coxiellosis is significantly associated with numerous risk factors including: the breed of animal, age, contact with small ruminants, and infestation with ticks. These findings indicate that C. burnetii is widely spread in cattle in Toukh, Qalubyia governorate. In conclusion, we recommended establishment of sanitary measures and an appropriate preventive strategy to reduce the spreading of the C. burnetii infection among farm animals and human in Qalubyia governorate.

Authors

Gehad F Elkhaiat,Faisal Arnaout,Hassan FM Mo'awad,Marawan A Marawan

Journal

Benha Veterinary Medical Journal

Published Date

2024/4/1

Design, synthesis, docking study, cytotoxicity evaluation, and PI3K inhibitory activity of Novel di-thiazoles, and bis (di-thiazoles)

A series of novel thiazole hybrids were designed and synthesized using a molecular hybridization approach to develop more potent Pi3k inhibitors for cancer treatment. As a result of the reaction of (phenylthiazol-5-yl)ethylidenehydrazine-1-carbothioamide with the corresponding bis-bromoacetyl derivatives, reasonable yields of novel bis-dithiazoles linked via aliphatic, aromatic, or heterocyclic cores were obtained. The structural details of the new compounds were confirmed using spectral data and elemental analysis. All of the proposed compounds were molecularly docked based on their structural similarity to the alpelisib pi3k inhibitor, and compounds 11e and 11d demonstrated very good binding modes that ranged between hydrogen and pi bonds. All compounds were tested for anticancer activity against HT29 colon cancer cells. The IC50 values for compounds 11d and 11e were 4.4 and 8.3 nM, respectively …

Authors

Mostafa E Salem,Mohamed Samir,Ahmed HM Elwahy,Ahmed M Farag,Abdelfattah M Selim,Aiman A Alsaegh,Marwa Sharaky,Noha Bagato,Ibrahim Taha Radwan

Journal

Journal of Molecular Structure

Published Date

2024/4/5

Serosurvey and Associated Risk Factors for Bovine Viral Diarrhea Virus Infection in Dromedary Camels in Egypt

Bovine viral diarrhea (BVD) is a disease that affects ruminants globally, including camels, and causing significant financial losses. The epidemiology of BVD in camels in Egypt are not well understood. Thus, this study aimed to determine the prevalence of anti-BVD virus (BVDV) antibodies in camels and identify the potential variables associated with the infection. A total of 400 camel sera from three Egyptian governorates were examined using commercial ELISA kit. The total seroprevalence was 4.8% in examined camels and the BVDV seropositivity were more prevalent in camels from Giza governorate. The highest seropositivity was found in aged camels more than 8 years (OR = 8.62, 95%CI: 1.03–71.87), camels from herd size less than 30 (OR = 4.20, 95%CI: 0.89–19.78), previously aborted animals (OR = 5.98, 95%CI: 2.12–16.92), and in animals kept in contact with sheep or goats (OR = 7.48, 95%CI: 2.56–21.86). Consequently, the camels may be a significant source of BVD infection for other ruminant animals in the same herd due to their susceptibility to the viral infection.

Authors

Abdelfattah Selim,Mohamed Marzok,Abdelhamed Abdelhady,Hattan S Gattan,Mohamed Salem,Mohammed Ali Al-Hammadi

Journal

Transboundary and Emerging Diseases

Published Date

2024/2/10

Synthesis of eco-friendly layered double hydroxide and nanoemulsion for jasmine and peppermint oils and their larvicidal activities against Culex pipiens Linnaeus

Mosquito-borne diseases represent a growing health challenge over time. Numerous potential phytochemicals are target-specific, biodegradable, and eco-friendly. The larvicidal activity of essential oils, a jasmine blend consisting of Jasmine oil and Azores jasmine (AJ) (Jasminum sambac and Jasminum azoricum) and peppermint (PP) Mentha arvensis and their nanoformulations against 2nd and 4th instar larvae of Culex pipiens, was evaluated after subjecting to different concentrations (62.5, 125, 250, 500, 1000, and 2000 ppm). Two forms of phase-different nanodelivery systems of layered double hydroxide LDH and oil/water nanoemulsions were formulated. The synthesized nanoemulsions showed particle sizes of 199 and 333 nm for AJ-NE and PP-NE, with a polydispersity index of 0.249 and 0.198, respectively. Chemical and physiochemical analysis of TEM, SEM, XRD, zeta potential, drug loading capacity …

Authors

Ibrahim Taha Radwan,Hanem F Khater,Shaimaa H Mohammed,Abdelwahab Khalil,Mohamed A Farghali,Mohammed G Mahmoud,Abdelfattah Selim,Eman A Manaa,Noha Bagato,Mohamed M Baz

Journal

Scientific Reports

Published Date

2024/3/22

Professor FAQs

What is Abdelfattah M selim's h-index at Benha University?

The h-index of Abdelfattah M selim has been 25 since 2020 and 26 in total.

What are Abdelfattah M selim's research interests?

The research interests of Abdelfattah M selim are: Infectious disease of animal, Bacteriology, Molecular biology

What is Abdelfattah M selim's total number of citations?

Abdelfattah M selim has 1,677 citations in total.

What are the co-authors of Abdelfattah M selim?

The co-authors of Abdelfattah M selim are Prof/ Abdullah D Alanazi, Mashal Almutairi, Ph.D., Roua Alsubki, Abdel-Fattah Ali, Elsayed Galila, Marawan Adel Marawan (マラワン アデル マラワン).

Co-Authors

H-index: 21
Prof/ Abdullah D Alanazi

Prof/ Abdullah D Alanazi

Shaqra University

H-index: 16
Mashal Almutairi, Ph.D.

Mashal Almutairi, Ph.D.

King Saud University

H-index: 13
Roua Alsubki

Roua Alsubki

King Saud University

H-index: 11
Abdel-Fattah Ali

Abdel-Fattah Ali

Benha University

H-index: 10
Elsayed Galila

Elsayed Galila

Menoufia University

H-index: 9
Marawan Adel Marawan (マラワン アデル マラワン)

Marawan Adel Marawan (マラワン アデル マラワン)

Benha University

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