Abdel-tawab AM

Abdel-tawab AM

Ain Shams University

H-index: 12

Africa-Egypt

About Abdel-tawab AM

Abdel-tawab AM, With an exceptional h-index of 12 and a recent h-index of 10 (since 2020), a distinguished researcher at Ain Shams University, specializes in the field of Pharmacology, Psychopharmacology, Neuropharmacology, Depression, Stress.

His recent articles reflect a diverse array of research interests and contributions to the field:

Cognitive effects ‎of the GSK-3 inhibitor “lithium” in LPS/chronic mild stress rat model of depression: ‎Hippocampal and cortical neuroinflammation and tauopathy

Effects of lithium on cytokine neuro-inflammatory mediators, Wnt/β-catenin signaling and microglial activation in the hippocampus of chronic mild stress-exposed rats☆

Abdel-tawab AM Information

University

Ain Shams University

Position

Professor Department of Pharmacology Faculty of Medicine Egypt.

Citations(all)

1041

Citations(since 2020)

385

Cited By

816

hIndex(all)

12

hIndex(since 2020)

10

i10Index(all)

14

i10Index(since 2020)

10

Email

University Profile Page

Ain Shams University

Abdel-tawab AM Skills & Research Interests

Pharmacology

Psychopharmacology

Neuropharmacology

Depression

Stress

Top articles of Abdel-tawab AM

Cognitive effects ‎of the GSK-3 inhibitor “lithium” in LPS/chronic mild stress rat model of depression: ‎Hippocampal and cortical neuroinflammation and tauopathy

Authors

Ahmed M. Abdel-Tawab Mai A. Ebeid a,Mohamed Z. Habib,Ahmed M. Mohamed,Yasser el Faramawy,‎Sherin S.T. Saad,Omnyah A. El-Kharashi,Hekmat M. El Magdoub,Hadwa A. Abd-‎Alkhalek,Sawsan Aboul-Fotouh

Journal

Neurotoxicology

Published Date

2021

Low-dose repeated lipopolysaccharide pre-challenge followed by chronic mild stress (LPS/CMS) protocol has been introduced as a rodent model of depression combining the roles of immune activation and chronic psychological stress. However, the impact of this paradigm on cognitive functioning has not been investigated hitherto.MethodsThis study evaluated LPS/CMS-induced cognitive effects and the role of glycogen synthase kinase-3β (GSK-3β) activation with subsequent neuroinflammation and pathological tau deposition in the pathogenesis of these effects using lithium (Li) as a tool for GSK-3 inhibition.ResultsLPS pre-challenge reduced CMS-induced neuroinflammation, depressive-like behavior and cognitive inflexibility. It also improved spatial learning but increased GSK-3β expression and exaggerated hyperphosphorylated tau accumulation in hippocampus and prefrontal cortex. Li ameliorated CMS …

Effects of lithium on cytokine neuro-inflammatory mediators, Wnt/β-catenin signaling and microglial activation in the hippocampus of chronic mild stress-exposed rats☆

Authors

Mohamed Z Habib,Mai A Ebeid,Yasser El Faramawy,Sherin ST Saad,M Hekmat,Azza A Attia,Sawsan Aboul-Fotouh,Ahmed M Abdel-Tawab

Journal

Toxicology and Applied Pharmacology

Published Date

2020/7/15

Microglial in vivo production of pro-inflammatory cytokines is central to the pathogenesis of multiple neurological disorders including depression, with a rising role of Wnt/β-catenin signaling as potential regulator of microglia-mediated neuro-inflammation. This study aimed at investigating the hippocampal expression of the Wnt/ß-catenin pathway in chronic mild stress (CMS)-exposed rats and the effects of Lithium (Li) on the expression of this pathway as a method to identify a plausible link between exposure to chronic stress, microglial activation, and neuroinflammation.MethodsThe effect of chronic administration of Li was investigated on behavioral changes, hippocampal expression of Wnt-DVL-GSK3β-β-catenin signaling pathway, and microglial activation in CMS-exposed male Wistar ratsResultsCMS induced a depressive-like behavior associated with increased pro-inflammatory microglial activation and reduced …

See List of Professors in Abdel-tawab AM University(Ain Shams University)

Abdel-tawab AM FAQs

What is Abdel-tawab AM's h-index at Ain Shams University?

The h-index of Abdel-tawab AM has been 10 since 2020 and 12 in total.

What are Abdel-tawab AM's top articles?

The articles with the titles of

Cognitive effects ‎of the GSK-3 inhibitor “lithium” in LPS/chronic mild stress rat model of depression: ‎Hippocampal and cortical neuroinflammation and tauopathy

Effects of lithium on cytokine neuro-inflammatory mediators, Wnt/β-catenin signaling and microglial activation in the hippocampus of chronic mild stress-exposed rats☆

are the top articles of Abdel-tawab AM at Ain Shams University.

What are Abdel-tawab AM's research interests?

The research interests of Abdel-tawab AM are: Pharmacology, Psychopharmacology, Neuropharmacology, Depression, Stress

What is Abdel-tawab AM's total number of citations?

Abdel-tawab AM has 1,041 citations in total.

What are the co-authors of Abdel-tawab AM?

The co-authors of Abdel-tawab AM are Maged El-Setouhy, Mariane George Tadros, Samar Kamal Kassim, May Hamza, Haidy E. Michel, Amal Mansour.

    Co-Authors

    H-index: 34
    Maged El-Setouhy

    Maged El-Setouhy

    Jazan University

    H-index: 22
    Mariane George Tadros

    Mariane George Tadros

    Ain Shams University

    H-index: 22
    Samar Kamal Kassim

    Samar Kamal Kassim

    Ain Shams University

    H-index: 15
    May Hamza

    May Hamza

    Ain Shams University

    H-index: 14
    Haidy E. Michel

    Haidy E. Michel

    Ain Shams University

    H-index: 9
    Amal Mansour

    Amal Mansour

    Ain Shams University

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