Abbas Rezaei

About Abbas Rezaei

Abbas Rezaei, With an exceptional h-index of 31 and a recent h-index of 24 (since 2020), a distinguished researcher at Isfahan University of Medical Sciences, specializes in the field of Immunology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Dogs may carry Leishmania tropica and Leishmania major in their blood circulation: a molecular and hematological study

Cardiovascular diseases risk predictors: ABO blood groups in a different role

Contradictory Effect of Lymphocyte Therapy and Prednisolone Therapy on CD3+ CD8+ CD56+ Natural Killer T Population in Women with Recurrent Spontaneous Abortion

Potential Therapeutic Effects of Human Amniotic Epithelial Cells on Gynecological Disorders Leading to Infertility or Abortion

Alterations of lipid profile in COVID-19: a narrative review

Is the neutrophil-to-lymphocyte ratio an exceptional indicator for metabolic syndrome disease and outcomes?

Anti Leishmanial Effect of Plantago psyllium (Ovate) and White Vinegar on Leishmania major Lesion in BALB/c Mice

Prenatal Exposure to L-Citrulline Has Positive Effects on Reflexive Motor Behavior in Newborn Mice

Abbas Rezaei Information

University

Isfahan University of Medical Sciences

Position

___

Citations(all)

3067

Citations(since 2020)

1754

Cited By

919

hIndex(all)

31

hIndex(since 2020)

24

i10Index(all)

79

i10Index(since 2020)

52

Email

University Profile Page

Isfahan University of Medical Sciences

Abbas Rezaei Skills & Research Interests

Immunology

Top articles of Abbas Rezaei

Dogs may carry Leishmania tropica and Leishmania major in their blood circulation: a molecular and hematological study

Authors

Ali Rezaei,Hassan Sharifi Yazdi,Ehsan Rakhshandehroo,Tina Yaghoobpour,Nooshin Derakhshandeh

Published Date

2024/3/27

BackgroundDogs may be infected with species of leishmania parasites that are disseminated through the body by blood circulation and invade the internal organs. Therefore, in this study, we attempted to find out the parasite in the blood of dogs in an area where the disease is more identified as the cutaneous type of leishmaniasis. A total of 135 blood samples were taken from dogs (50 Anaemic and 85 normal) and subjected to PCR reaction using ITS-1 and ITS-2 regions of the ribosomal gene.ResultsTotally, seven samples (5.1%) were positive, six were identified as L. tropica and one sample was L. major. This result was interesting because we did not find any case of L. infantum which is always known for visceral infection. In addition, no sign of cutaneous lesions or a significant disease was seen in the animals infected with both species. From 48 dogs suffered from anemia, 2 cases were Leishmania positive. The mean value of hematological parameters in the infected dogs was within the normal range except for a significant reduction in the platelet measures (p< 0.05).ConclusionsOur data revealed that both Leishmania species, tropica and major, may manifested by viscerotropic leishmaniasis. More investigations are needed to find the conditions that those species decide to select the type of infection. Moreover, our data emphasize the role of asymptomatic dogs to carry the Leishmania parasite.

Cardiovascular diseases risk predictors: ABO blood groups in a different role

Authors

Sina Neshat,Abbas Rezaei,Armita Farid,Salar Javanshir,Fatemeh Dehghan Niri,Padideh Daneii,Kiyan Heshmat-Ghahdarijani,Setayesh Sotoudehnia Korani

Published Date

2024/3/1

Cardiovascular diseases (CVDs) pose a serious threat to people’s health, with extremely high global morbidity, mortality, and disability rates. This study aimed to review the literature that examined the relationship between blood groups and CVD. Many studies have reported that non-O blood groups are associated with an increased risk and severity of coronary artery disease and acute coronary syndromes. Non-O blood groups increase the risk and severity of these conditions by increasing von Willebrand factor and plasma cholesterol levels and inducing endothelial dysfunction and inflammation. They have also been linked with increased coronary artery calcification, coronary lesion complexity, and poor collateral circulation. Blood groups also affect the prognosis of coronary artery disease and acute coronary syndrome and can alter the rate of complications and mortality. Several cardiovascular complications …

Contradictory Effect of Lymphocyte Therapy and Prednisolone Therapy on CD3+ CD8+ CD56+ Natural Killer T Population in Women with Recurrent Spontaneous Abortion

Authors

Fatemeh Rezayat,Nafiseh Esmaeil,Abbas Rezaei,Roya Sherkat

Journal

Journal of Human Reproductive Sciences

Published Date

2023/7/1

Background:Natural killer T (NKT) cells are influential immune cells in pregnancy failures, including recurrent spontaneous abortion (RSA). Different approaches are used for these disorders due to their effects on maternal immunomodulation.Aims:In the present study, we compared the effects of two typical immunotherapies (lymphocyte immunotherapy [LIT] and low-dose prednisolone) on CD3+ CD56+ CD16+ and CD3+ CD56+ CD8+ cells as two distinct subsets of NKT cells in Women with RSA.Settings and Design:This study was a comparative cohort study conducted from 2021 to 2022. One hundred and five women with RSA were distributed into three treatment groups randomly.Materials and Methods:Fifty women in the group of low-dose prednisolone therapy, fifty women in the LIT group and five women without any treatment as the control group were included in the study. NK and NKT cell subsets were …

Potential Therapeutic Effects of Human Amniotic Epithelial Cells on Gynecological Disorders Leading to Infertility or Abortion

Authors

Fatemeh Rezayat,Nafiseh Esmaeil,Abbas Rezaei

Published Date

2023/2

The induction of feto-maternal tolerance, fetal non-immunogenicity, and the regulation of mother’s immune system are essential variables in a successful pregnancy. Fetal membranes have been used as a source of stem cells and biological components in recent decades. Human amniotic epithelial cells (hAEC) have stem/progenitor characteristics like those found in the amniotic membrane. Based on their immunomodulatory capabilities, recent studies have focused on the experimental and therapeutic applications of hAECs in allograft transplantation, autoimmune disorders, and gynecological problems such as recurrent spontaneous abortion (RSA), recurrent implantation failure (RIF), and premature ovarian failure (POF). This review discusses some of the immunomodulatory features and therapeutic potential of hAECs in preventing infertility, miscarriage, and implantation failure by controlling the maternal …

Alterations of lipid profile in COVID-19: a narrative review

Authors

Abbas Rezaei,Sina Neshat,Kiyan Heshmat-Ghahdarijani

Published Date

2022/3/1

The COVID-19 pandemic has led to over 100 million infections and over 3 million deaths worldwide. Understanding its pathogenesis is crucial to guide prognostic and therapeutic implications. Viral infections are known to alter the lipid profile and metabolism of their host cells, similar to the case with MERS and SARS-CoV-2002. Since lipids play various metabolic roles, studying lipid profile alterations in COVID-19 is an inevitable step as an attempt to achieve better therapeutic strategies, as well as a potential prognostic factor in the course of this disease. Several studies have reported changes in lipid profile associated with COVID-19. The most frequently reported changes are a decline in serum cholesterol and ApoA1 levels and elevated triglycerides. The hyper-inflammatory state mediated by the Cytokine storm disturbs several fundamental lipid biosynthesis pathways. Virus replication is a process that drastically …

Is the neutrophil-to-lymphocyte ratio an exceptional indicator for metabolic syndrome disease and outcomes?

Authors

Parisa Hashemi Moghanjoughi,Sina Neshat,Abbas Rezaei,Kiyan Heshmat-Ghahdarijani

Published Date

2022/3/1

ObjectivesTo show that there is relation between neutrophil-to-lymphocyte ratio (NLR) and metabolic syndrome and also, its components.FindingsMetabolic syndrome is associated with elevated fasting blood glucose, increased blood pressure, central obesity, decreased high-density lipoprotein, and increased triglyceride levels. Because of its growing incidence and prevalence and the effect that it has on developing other noncommunicable diseases, the importance gets even more value. The prediction and control of this disease in its early stages and in the most inexpensive way is of crucial need. Due to the role of chronic low-grade inflammation in metabolic syndrome, cytokines and inflammatory factors (like interleukin-6 and tumor necrosis factor-α) play a critical role on this phenomenon. The NLR is an inflammatory marker that has an unchallenging availability and has a reasonable cost. The NLR is related to …

Anti Leishmanial Effect of Plantago psyllium (Ovate) and White Vinegar on Leishmania major Lesion in BALB/c Mice

Authors

Abdolali Moshfe,Keianoush Karami,Maryam Bahmani,Mohsen Naghmachi,Shahrbanoo Askarian,Abbas Rezaei,Roohallah Zare,Ali Jamshidi

Journal

Journal of Arthropod-Borne Diseases

Published Date

2022/3

Background:Leishmania major is the etiologic agent of zoonotic cutaneous leishmaniasis in Iran, and glucantime injection is currently used for its treatment. This study aimed to evaluate the anti-leishmanial effect of topical Plantago psyllium and white vinegar in L. major infected BALB/c mice.Methods:Thirty infected mice were divided into five groups as follows: Group 1: treated with the combination of ovata powder and white vinegar, Group 2: treated with glucantime, Group 3: treated with white vinegar, Group 4: treated with the combination of ovata powder and water, and Group 5: without any treatment. All the groups were treated for 18 days. Lesion size was measured, and final smears were prepared for microscopic examination.Results:The findings indicated that the difference in the mean areas of the ulcers in all the groups before and after treatment was not significant, except for the second (glucantime) and …

Prenatal Exposure to L-Citrulline Has Positive Effects on Reflexive Motor Behavior in Newborn Mice

Authors

P Haramipour,Hassanpour Sh,A Rezaei

Journal

Archives of Razi Institute

Published Date

2022/10

L-citrulline (L-cit) is a nonessential amino acid that interacts with the veracity of neurotransmitters in the brain and might have a positive effect on fetal growth. However, there is no information about the possible effect of L-cit on reflexive motor behavior. Thus, this study aimed to determine the effects of prenatal exposure to L-cit on reflexive motor behavior in mice offspring. Forty pregnant female mice were allocated into four groups. In the control group, mice received water, while in groups 2-4, female mice orally gavage with L-cit (25, 50, and 100 mg/kg) at 5, 8, 11, 14, and 17 days of gestation (GD). Following delivery, pups were selected, and reflexive motor behaviors were determined using ambulation, hind-limb foot angle, surface righting, hind-limb strength, grip strength, front limb suspension, and negative geotaxis tests. Also, serum Nitric oxide (NO), malondialdehyde (MDA), superoxide dismutase (SOD) and …

The tangled web of dyslipidemia and cancer: Is there any association?

Authors

Sina Neshat,Abbas Rezaei,Armita Farid,Rojin Sarallah,Salar Javanshir,Sarina Ahmadian,Gelayol Chatrnour,Padideh Daneii,Kiyan Heshmat-Ghahdarijani

Published Date

2022/1/1

Cancer is a primary cause of mortality around the world and imposes a significant physiological, psychological, and financial burden on patients. Lipids regulate cell cycle progression and affect cell proliferation, migration, and apoptosis. Therefore, alterations in serum lipid levels might contribute to carcinogenesis. In this article, we review the relationships between triglyceride (TG), total cholesterol, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels and different types of cancer. Then, we examine the association between cancer and familial hypercholesterolemia. Finally, we evaluate the impact of statins on different types of cancer. Increased total cholesterol has been reported to increase cellular proliferation and angiogenesis in tumors and inhibit apoptosis. Increased LDL-C has been reported to induce inflammation and increase susceptibility to oxidative damage …

The context and basis of Amir Kabir's reforms

Authors

Abbas Rezaei

Journal

Socio-political studies of Iran's contemporary history.

Published Date

2022/6/22

Among the figures of Iran's contemporary history, Amir Kabir is considered one of the great architects of Iran's reform project, who, by carrying out practical political, economic and social reforms, laid the foundation for modernity in Iran. However, his untimely murder dealt a terrible blow to the changing body of Iran. However, his actions and reforms left an undeniable impact on the process of reforming Iran in the following periods, so that many of the reformed and modern statesmen of the Nasser era, who pushed forward the trend of Iranian modernization in the field of thought and practice, were among the successors of Amir Kabir. Examining the intellectual foundations and model of Amir Kabir's reforms during his presidency is the main issue of this article.

Liver resection promotes (regulates) proinflammatory cytokines in patients with hepatocellular carcinoma

Authors

Farshid Fathi,Behnam Sanei,Mazdak Ganjalikhani Hakemi,Reza F Saidi,Abbas Rezaei

Journal

Canadian Journal of Gastroenterology and Hepatology

Published Date

2021/4/23

Background. Several animal studies have shown the roles of cytokines in regulating liver regeneration following liver resection (LR), which is a type of surgery designed to remove cancerous tumors from the liver. This study investigated how the expressions and serum levels of some pro- and anti-inflammatory cytokines in patients with hepatocellular carcinoma (HCC) were changed during LR. Methods. Liver tissues from 15 patients with HCC were collected and the levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), IL-1α, IL-1 β, IL-10, and transforming growth factor-beta1 (TGF-β1) were assessed using real-time PCR assay at different times before and after LR. The serum values of TNF-α and IL-6 were also measured by ELISA. Results. After 60 and 90 minutes of LR, IL-6 gene expression was significantly increased . The same trend was also observed in TNF-α expression after 90 minutes of LR . No significant changes were observed in the expressions of IL-1α, IL-1β, IL-10, and TGF-β1 before and after LR. In addition, LR had significant effects on TNF-α and IL-6 serum levels . Conclusion. Our data provided further evidence to reveal that IL-6 and TNF-α cytokines are critical to improve liver regeneration.

DOWN-REGULATION OF INFLAMMATORY SIGNALING PATHWAYS DESPITE UP-REGULATIONOF TOLL-LIKE RECEPTORS; THE EFFECTS OF CORTICOSTEROID THERAPY IN BRAIN-DEAD

Authors

Reza Jafari,Reza Aflatoonian,Reza Falak,Gholamreza Pourmand,Sanaz Dehghani,Mojgan Mortazavi,Adeleh Adelipour,Abbas Rezaei,Nader Tajik

Journal

Molecular immunology

Published Date

2018/2/1

BackgroundThe brain death of a potential organ donor induces a systemic inflammatory response, resulting in inferior organ quality and function. Our study aimed to evaluate the effects of methylprednisolone (MPN) therapy on pattern recognition receptor (PRR) signaling in potential brain-dead (BD) kidney donors.Material and methodsTo evaluate the effects of MPN therapy on PRR signaling in BD kidney donors we performed a prospective randomized treatment-versus-control study. Fifty-one potential kidney donors were randomly divided into three groups: brain-dead donors (BDDs) who received 15 mg/kg/d of methylprednisolone (group T1, n = 17), BDDs who received 15 mg/kg/d of MPN at the time of filling consent for kidney donation and 100 mg/2 h until kidney harvest (group T2, n = 17), and normal donors as controls n = 17. Gene expression for Toll-like receptors (TLRs) 1–9 and their signaling …

Phycocyanin C a natural product with impressive therapeutic efficacy for inhibition of breast tumors’ growth and metastasis in vivo

Authors

Amirhosein Kefayat,Mohadeseh Yuosefzadeh,Parvin Goli,Alireza Babayi,Abbas Rezaei,Nafiseh Esmaeil

Journal

Middle East Journal of Cancer

Published Date

2021/4/1

Background Several studies have reported the anticancer effect of phycocyanin C, a natural extract isolated from the algae Arthrospira platensis. However, its therapeutic effects on the growth of breast cancer and its metastasis have not been determined yet. Method In this case-control study, we employed phycocyanin C for the treatment of 4T1 breast tumor as an applicable experimental animal model for human mammary cancer and metastasis. BALB/c mice were injected subcutaneously (s.c) into the 4th abdominal mammary fat pad with 1×106 4T1 cells. We randomly divided the mice into two groups; one group of mice were injected with PBS as the control, and the other group was intraperitoneally injected with phycocyanin C (80 mg/kg daily for 20 days). Tumor growth and metastasis were assessed in both groups. Results Phycocyanin C significantly inhibited 4T1 breast tumors growth (P<0.05). The mean tumors volumes at the control group were 2.73 times higher than those of the treatment group. In addition, phycocyanin C treatment could significantly inhibit the formation of metastasis colonies at vital organs like spleen, liver, and lung. Moreover, the survival rate of the tumor-bearing mice increased after about 22 days by phycocyanin C treatment in comparison with the control. Conclusion This is the first report demonstrating the anticancer effects of phycocyanin C on 4T1 breast tumor in vivo. Overall, our findings provided convincing evidence for the application of phycocyanin C as an anticancer therapeutic agent.

INNATE INFLAMMATORY GENE EXPRESSION PROFILING IN POTENTIAL BRAIN-DEAD DONORS: DETAILED INVESTIGATION OF THE EFFECT OFCOMMON CORTICOSTEROID THERAPY

Authors

Reza Gholamnezhadjafari,Nader Tajik,Reza Falak,Reza Aflatoonian,Sanaz Dehghan,Abbas Rezaei

Journal

Innate Immunity

Published Date

2017/7

Our study aimed to assess the influence of common methylprednisolone therapy on innate inflammatory factors in potential brain-dead organ donors (BDDs). The study groups consisted of 50 potential BDDs who received 15 mg/kg/d methylprednisolone and 25 live organ donors (LDs) as control group. Innate immunity gene expression profiling was performed by RT-PCR array. Soluble serum cytokines and chemokines, complement components, heat shock protein 70 (HSP70) and high mobility group box-1 (HMGB1) were measured by ELISA. Surface expression of TLR2 and TLR4 were determined using flow cytometry. Gene expression profiling revealed up-regulation of TLRs 1, 2, 4, 5, 6, 7 and 8, MYD88, NF-κB, NF-κB1A, IRAK1, STAT3, JAK2, TNF-α, IL-1β, CD86 and CD14 in the BDD group. Remarkably, the serum levels of C-reactive protein and HSP70 were considerably higher in the BDD group. In addition …

The role of the Qajar Period Press in Promoting the Position of the Persian Gulf as a Member of the Presidency in the Body of Iran (Emphasis on the Newspapers Habl al-Matin …

Authors

Abbas Rezaei,Qobad Mansourbakht

Journal

Research Journal of Iran Local Histories

Published Date

2021/2/19

The Persian Gulf, as Iran's sea route to the world and vice versa, has been under the political, cultural and economic sovereignty of Iran for most of history. This rule was the natural and logical consequence of the action of the largest country on the northern shores of the Persian Gulf in defense of its existence and security, which has taken place unequivocally in most historical periods. With the rise of colonialism and the arrival of European colonial powers; Portugal, Spain, the Netherlands, and Britain opposed the Persian Gulf, Iranian sovereignty in the Persian Gulf, and confronted Iran with one of the greatest problems of the modern era. Continuation of this led to the reduction of Iran's power and the further consolidation of British power, and eventually the undisputed power of this country throughout the Persian Gulf in the Qajar era. With the British invasion of the Iranian coast and the capture of Bushir during the Herat War, the conflict with Iranian rule in the Persian Gulf and the de-Iranianization of this great waterway reached its peak. From then on, the reaction and extensive efforts of the Iranians to maintain sovereignty in the Persian Gulf and promote its place in the Iranian mentality began through the production of concepts, meanings and ideas appropriate to the new era in the form of a new Persian Gulf discourse. The findings of this study, based on a combination of causal-rational method, show that the Qajar period press played the main role in promoting the position of the Persian Gulf from natural areas to "member of the body of the body of Iran" in the form of a new Persian Gulf discourse.

Spermatozoa induce maternal mononuclear cells for production of antibody with cytotoxic activity on paternal blood mononuclear cells

Authors

Nasrin Sereshki,Alireza Andalib,Mohadeseh Toghyani,Hossein Motedayyen,Mohammad Sadegh Hesamian,Abbas Rezaei,David Wilkinson

Journal

Cell Journal (Yakhteh)

Published Date

2021/8

ObjectiveThe maternal immune response to paternal antigens is induced at insemination. We believe that pregnancy protective alloantibodies, such as anti-paternal cytotoxic antibody (APCA), may be produced against the paternal antigens in the context of stimulated immunity at insemination and that they increase during pregnancy. APCA is necessary for pregnancy. It is directed towards paternal human leucocyte antigens (HLAs) and has cytotoxic activity against paternal leucocytes. The present study aims to determine whether APCA is produced by the maternal peripheral blood mononuclear cells (PBMCs) in contact with the husband’s spermatozoa and to evaluate the relation of APCA production with HLA class I and II expressions by spermatozoa in fertile couples.Materials and MethodsThis cross-sectional study included 30 fertile couples with at least one child. The maternal PBMCs were co-cultured with the …

Thyroid peroxidase in human endometrium and placenta: a potential target for anti-TPO antibodies

Authors

Reyhane Rahnama,Ahmad-Reza Mahmoudi,Somayeh Kazemnejad,Mansour Salehi,Ataollah Ghahiri,Haleh Soltanghoraee,Sedigheh Vafaei,Abbas Rezaei,Amir Hassan Zarnani

Journal

Clinical and Experimental Medicine

Published Date

2021/2

Autoimmune thyroid disease is the most common endocrine disorder during pregnancy. Thyroid autoantibodies (TAs) have been suggested to serve a role in implantation failure and spontaneous abortion. Until now, there are no data on the potential interaction of TAs with human reproductive organs. Here, we set out for the first time to test this hypothesis by studying the expression of thyroid peroxidase (TPO) at gene and protein level in human reproductive organs. Endometrial samples were taken from normal women, and placenta tissues were collected after full-term caesarian section. Expression of TPO messenger RNA (mRNA) was investigated by qRT-PCR. In addition, polyclonal anti-TPO antibodies were produced and the expression of TPO protein in mentioned tissues was evaluated by immunohistochemistry and Western blot analysis. The reactivity of anti-TPO antibody in human embryos was …

Critique of the English version of the Persian Gulf

Authors

Abbas Rezaei,Ghobad Mansoorbakht

Journal

Journal of Historical Researches of Iran and Islam

Published Date

2021/7/23

With the arrival of the new era, the Persian Gulf, like all eastern lands, faced a new problem. With the presence of Portugal, Spain, France, the Netherlands, and the United Kingdom in the region, the old order and balance faced new and unprecedented opposition, and as a result new political, military, and trade relations were established that upset that balance. Eventually, after defeating rivals and absolute sovereignty over India and then the Persian Gulf, Britain became the absolute ruler of this canal.The result was the absolute domination of foreigners over the region. Since then, in order to maintain its presence, the United Kingdom has tried to provide a legitimate picture of its presence in the region and to present a new historiography of the Persian Gulf by presenting an English account of the developments in this region.If the first issue was an objective issue, from here on, mental and epistemological issues arose because a new image of the Persian Gulf was presented, which challenged the old image. The research findings, which are based on a combination of comparative and rational methods, show that despite providing a lot of information, the presented image not only does not correspond to the historical facts of the Persian Gulf and the situation in the region during the creation of these works. Orientalism and the interests of the British East India Company.

Research Article Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma

Authors

Farshid Fathi,Behnam Sanei,Mazdak Ganjalikhani Hakemi,Reza F Saidi,Abbas Rezaei

Published Date

2021

Background Several animal studies have shown the roles of cytokines in regulating liver regeneration following liver resection (LR), which is a type of surgery designed to remove cancerous tumors from the liver. is study investigated how the expressions and serum levels of some pro-and anti-inflammatory cytokines in patients with hepatocellular carcinoma (HCC) were changed during LR. Methods Liver tissues from 15 patients with HCC were collected and the levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), IL-1α, IL-1 β, IL-10, and transforming growth factor-beta1 (TGF-β1) were assessed using real-time PCR assay at different times before and after LR. e serum values of TNF-α and IL-6 were also measured by ELISA. Results After 60 and 90 minutes of LR, IL-6 gene expression was significantly increased (P< 0. 001− 0. 05). e same trend was also observed in TNF-α expression after 90 minutes of LR (P< 0. 01). No significant changes were observed in the expressions of IL-1α, IL-1β, IL-10, and TGF-β1 before and after LR. In addition, LR had significant effects on TNF-α and IL-6 serum levels (P< 0. 05− 0. 0001). Conclusion Our data provided further evidence to reveal that IL-6 and TNF-α cytokines are critical to improve liver regeneration.

Progesterone-induced blocking factor (PIBF) influences the expression of membrane progesterone receptors (mPRs) on peripheral CD4+ T lymphocyte cells in normal fertile females

Authors

Mitra Rafiee,Abbas Rezaei,Razieh Alipour,Nasrin Sereshki,Narges Motamedi,Mohsen Naseri

Journal

Hormones

Published Date

2021/9

PurposeProgesterone-induced blocking factor (PIBF) is a protein secreted by lymphocytes exposed to progesterone (P4). P4 and PIBF have immunomodulatory effects on peripheral CD4+ T cells during normal pregnancy. Membrane progesterone receptors (mPRs) may correlate with the immunomodulatory properties of P4 on T cells. Variation in expression of mPRs may influence P4 regulatory performance during pregnancy. On the other hand, PIBF increases in pregnant normal women compared to women who have experienced abortion. The present study aimed to determine whether PIBF, in addition to having a direct influence on the immune system, can affect P4 performance through its effect on mPR expression. Such novel research findings demonstrate the importance of PIBF in the maintenance of pregnancy.MethodsIsolated peripheral blood mononuclear cells (PBMCs) from 30 healthy women were …

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Abbas Rezaei FAQs

What is Abbas Rezaei's h-index at Isfahan University of Medical Sciences?

The h-index of Abbas Rezaei has been 24 since 2020 and 31 in total.

What are Abbas Rezaei's top articles?

The articles with the titles of

Dogs may carry Leishmania tropica and Leishmania major in their blood circulation: a molecular and hematological study

Cardiovascular diseases risk predictors: ABO blood groups in a different role

Contradictory Effect of Lymphocyte Therapy and Prednisolone Therapy on CD3+ CD8+ CD56+ Natural Killer T Population in Women with Recurrent Spontaneous Abortion

Potential Therapeutic Effects of Human Amniotic Epithelial Cells on Gynecological Disorders Leading to Infertility or Abortion

Alterations of lipid profile in COVID-19: a narrative review

Is the neutrophil-to-lymphocyte ratio an exceptional indicator for metabolic syndrome disease and outcomes?

Anti Leishmanial Effect of Plantago psyllium (Ovate) and White Vinegar on Leishmania major Lesion in BALB/c Mice

Prenatal Exposure to L-Citrulline Has Positive Effects on Reflexive Motor Behavior in Newborn Mice

...

are the top articles of Abbas Rezaei at Isfahan University of Medical Sciences.

What are Abbas Rezaei's research interests?

The research interests of Abbas Rezaei are: Immunology

What is Abbas Rezaei's total number of citations?

Abbas Rezaei has 3,067 citations in total.

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