Aaron T Griffin
Columbia University in the City of New York
H-index: 6
North America-United States
Top articles of Aaron T Griffin
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in … | Cancer Research | Ester Calvo Fernandez Lorenzo Tomassoni Xu Zhang Aleksandar Obradovic Pasquale Laise | 2024/3/22 |
Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations | bioRxiv | Ester Calvo Fernandez Lorenzo Tomassoni Xu Zhang Junqiang Wang Aleksandar Obradovic | 2024/3/17 |
Abstract PR01: Identification and pharmacological targeting of treatment-resistant, stem-like breast cancer cells for combination therapy | Cancer Research | Jeremy Worley Heeju Noh Daoqi You Mikko M Turunen Hongxu Ding | 2024/2/1 |
Immunoproteasome expression and checkpoint blockade response in advanced non-small cell lung cancer | Cancer Research | Vivek Naranbhai Arvind Ravi Matthew Hellmann Monica Arniella Mark Holton | 2023/4/4 |
Network-based inference identifies cell state-specific drugs targeting master regulator vulnerabilities in diffuse midline glioma | Cancer Research | Ester Calvo Fernandez Junqiang Wang Xu Zhang Hong-Jian Wei Hanna E Minns | 2023/4/4 |
NaRnEA: an information theoretic framework for gene set analysis | Entropy | Aaron T Griffin Lukas J Vlahos Codruta Chiuzan Andrea Califano | 2023/3/21 |
Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis | bioRxiv | George Rosenberger Wenxue Li Mikko Turunen Jing He Prem S Subramaniam | 2023/2/16 |
DIPG-49. A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA | Neuro-Oncology | Ester Calvo Fernández Junqiang Wang Xu Zhang Hong-Jian Wei Hanna Minns | 2023/6/1 |
Identifying and Targeting Master Regulators of Drug Resistance in Lung Adenocarcinoma through Network Analysis of Tumor Transcriptomic Data | Aaron Timothy Griffin | 2023 | |
Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer | Nature genetics | Arvind Ravi Matthew D Hellmann Monica B Arniella Mark Holton Samuel S Freeman | 2023/5 |
DIPG-57. A systems biology approach to defining and targeting master regulator dependencies from bulk and single-Cell RNA-seq in diffuse midline glioma (DMG) | Neuro-Oncology | Ester Calvo Fernández Junqiang Wang Aaron Griffin Hanna Minns Hong-Jian Wei | 2022/6/1 |
Abstract A007: Pancreatic cancer comprises co-existing transcriptional states regulated by distinct master regulator programs | Cancer Research | Pasquale Laise Mikko Turunen Hans Carlo Maurer Alvaro Curiel Garcia Ela Elyada | 2022/11/15 |
A systems biology approach to defining tumor heterogeneity, prognostic and targetable master regulator protein signatures from bulk and single cell RNA-seq in diffuse midline … | Cancer Research | Ester Calvo Fernández Junqiang Wang Aaron T Griffin Luca Szalontay Stergios Zacharoulis | 2022/6/15 |
Integrative analysis of checkpoint blockade response in advanced non-small cell lung cancer | bioRxiv | Arvind Ravi Justin F Gainor Monica B Arniella Mark Holton Samuel S Freeman | 2022/3/23 |
Elucidation and pharmacological targeting of master regulator proteins representing mechanistic determinants of breast cancer stem-like tumor initiating cell state | Cancer Research | Jeremy Worley Hongxu Ding Heeju Noh Evan Paull Aaron T Griffin | 2022/6/15 |
Pancreatic cancer comprises co-existing transcriptional states regulated by distinct master regulator programs. | Cancer Research | Pasquale Laise Mikko Turunen Hans Carlo Maurer Alvaro Curiel Garcia Ela Elyada | 2022 |
Identifying synergistic master regulators of pancreatic ductal adenocarcinoma tumorigenesis through CRISPR/Cas9 combinatorial genetic screens | Cancer Research | Aaron T Griffin Mikko Turunen Lorenzo Tomassoni Kenneth P Olive Pasquale Laise | 2022/6/15 |
Clinical characteristics and molecular features of non-small cell lung cancers (NSCLCs) following disease progression on immune checkpoint inhibitors (ICIs). | Justin F Gainor Arvind Ravi Mark M Awad Mark Holton Monica Arniella | 2022/6/1 | |
Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses | Nature biotechnology | Joshua Broyde David R Simpson Diana Murray Evan O Paull Brennan W Chu | 2021/2 |
A genome-wide copper-sensitized screen identifies novel regulators of mitochondrial cytochrome c oxidase activity | Journal of Biological Chemistry | Natalie M Garza Aaron T Griffin Mohammad Zulkifli Chenxi Qiu Craig D Kaplan | 2021/1/1 |