Aaron T Griffin

Aaron T Griffin

Columbia University in the City of New York

H-index: 6

North America-United States

About Aaron T Griffin

Aaron T Griffin, With an exceptional h-index of 6 and a recent h-index of 6 (since 2020), a distinguished researcher at Columbia University in the City of New York, specializes in the field of Systems Biology, Cancer, Genomics, Bioinformatics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in …

Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations

Abstract PR01: Identification and pharmacological targeting of treatment-resistant, stem-like breast cancer cells for combination therapy

Immunoproteasome expression and checkpoint blockade response in advanced non-small cell lung cancer

Network-based inference identifies cell state-specific drugs targeting master regulator vulnerabilities in diffuse midline glioma

NaRnEA: an information theoretic framework for gene set analysis

Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis

DIPG-49. A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA

Aaron T Griffin Information

University

Position

Columbia University College of Physicians and Surgeons

Citations(all)

237

Citations(since 2020)

161

Cited By

118

hIndex(all)

6

hIndex(since 2020)

6

i10Index(all)

6

i10Index(since 2020)

5

Email

University Profile Page

Columbia University in the City of New York

Google Scholar

View Google Scholar Profile

Aaron T Griffin Skills & Research Interests

Systems Biology

Cancer

Genomics

Bioinformatics

Top articles of Aaron T Griffin

Title

Journal

Author(s)

Publication Date

Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in …

Cancer Research

Ester Calvo Fernandez

Lorenzo Tomassoni

Xu Zhang

Aleksandar Obradovic

Pasquale Laise

...

2024/3/22

Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations

bioRxiv

Ester Calvo Fernandez

Lorenzo Tomassoni

Xu Zhang

Junqiang Wang

Aleksandar Obradovic

...

2024/3/17

Abstract PR01: Identification and pharmacological targeting of treatment-resistant, stem-like breast cancer cells for combination therapy

Cancer Research

Jeremy Worley

Heeju Noh

Daoqi You

Mikko M Turunen

Hongxu Ding

...

2024/2/1

Immunoproteasome expression and checkpoint blockade response in advanced non-small cell lung cancer

Cancer Research

Vivek Naranbhai

Arvind Ravi

Matthew Hellmann

Monica Arniella

Mark Holton

...

2023/4/4

Network-based inference identifies cell state-specific drugs targeting master regulator vulnerabilities in diffuse midline glioma

Cancer Research

Ester Calvo Fernandez

Junqiang Wang

Xu Zhang

Hong-Jian Wei

Hanna E Minns

...

2023/4/4

NaRnEA: an information theoretic framework for gene set analysis

Entropy

Aaron T Griffin

Lukas J Vlahos

Codruta Chiuzan

Andrea Califano

2023/3/21

Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis

bioRxiv

George Rosenberger

Wenxue Li

Mikko Turunen

Jing He

Prem S Subramaniam

...

2023/2/16

DIPG-49. A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA

Neuro-Oncology

Ester Calvo Fernández

Junqiang Wang

Xu Zhang

Hong-Jian Wei

Hanna Minns

...

2023/6/1

Identifying and Targeting Master Regulators of Drug Resistance in Lung Adenocarcinoma through Network Analysis of Tumor Transcriptomic Data

Aaron Timothy Griffin

2023

Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

Nature genetics

Arvind Ravi

Matthew D Hellmann

Monica B Arniella

Mark Holton

Samuel S Freeman

...

2023/5

DIPG-57. A systems biology approach to defining and targeting master regulator dependencies from bulk and single-Cell RNA-seq in diffuse midline glioma (DMG)

Neuro-Oncology

Ester Calvo Fernández

Junqiang Wang

Aaron Griffin

Hanna Minns

Hong-Jian Wei

...

2022/6/1

Abstract A007: Pancreatic cancer comprises co-existing transcriptional states regulated by distinct master regulator programs

Cancer Research

Pasquale Laise

Mikko Turunen

Hans Carlo Maurer

Alvaro Curiel Garcia

Ela Elyada

...

2022/11/15

A systems biology approach to defining tumor heterogeneity, prognostic and targetable master regulator protein signatures from bulk and single cell RNA-seq in diffuse midline …

Cancer Research

Ester Calvo Fernández

Junqiang Wang

Aaron T Griffin

Luca Szalontay

Stergios Zacharoulis

...

2022/6/15

Integrative analysis of checkpoint blockade response in advanced non-small cell lung cancer

bioRxiv

Arvind Ravi

Justin F Gainor

Monica B Arniella

Mark Holton

Samuel S Freeman

...

2022/3/23

Elucidation and pharmacological targeting of master regulator proteins representing mechanistic determinants of breast cancer stem-like tumor initiating cell state

Cancer Research

Jeremy Worley

Hongxu Ding

Heeju Noh

Evan Paull

Aaron T Griffin

...

2022/6/15

Pancreatic cancer comprises co-existing transcriptional states regulated by distinct master regulator programs.

Cancer Research

Pasquale Laise

Mikko Turunen

Hans Carlo Maurer

Alvaro Curiel Garcia

Ela Elyada

...

2022

Identifying synergistic master regulators of pancreatic ductal adenocarcinoma tumorigenesis through CRISPR/Cas9 combinatorial genetic screens

Cancer Research

Aaron T Griffin

Mikko Turunen

Lorenzo Tomassoni

Kenneth P Olive

Pasquale Laise

...

2022/6/15

Clinical characteristics and molecular features of non-small cell lung cancers (NSCLCs) following disease progression on immune checkpoint inhibitors (ICIs).

Justin F Gainor

Arvind Ravi

Mark M Awad

Mark Holton

Monica Arniella

...

2022/6/1

Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses

Nature biotechnology

Joshua Broyde

David R Simpson

Diana Murray

Evan O Paull

Brennan W Chu

...

2021/2

A genome-wide copper-sensitized screen identifies novel regulators of mitochondrial cytochrome c oxidase activity

Journal of Biological Chemistry

Natalie M Garza

Aaron T Griffin

Mohammad Zulkifli

Chenxi Qiu

Craig D Kaplan

...

2021/1/1

See List of Professors in Aaron T Griffin University(Columbia University in the City of New York)

Co-Authors

H-index: 132
Barry Honig

Barry Honig

Columbia University in the City of New York

H-index: 91
Andrea Califano

Andrea Califano

Columbia University in the City of New York

H-index: 35
Kenneth P. Olive

Kenneth P. Olive

Columbia University in the City of New York

H-index: 34
Faiyaz Notta

Faiyaz Notta

University of Toronto

H-index: 24
Alina Iuga

Alina Iuga

University of North Carolina at Chapel Hill

H-index: 23
Sherine Chan

Sherine Chan

Medical University of South Carolina

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