Aaron Cheng

Aaron Cheng

Harvard University

H-index: 5

North America-United States

About Aaron Cheng

Aaron Cheng, With an exceptional h-index of 5 and a recent h-index of 5 (since 2020), a distinguished researcher at Harvard University, specializes in the field of genetics, hematology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Impact of Degree and Duration of Iron Overload on Incidence of Diabetes Mellitus, Cardiac Disease, and Death in Congenital Hemolytic Anemias

A case report of mesenteric and portal vein thrombosis in a patient with Fusobacterium nucleatum bacteremia

Dissecting the Genetic Architecture of Fetal Hemoglobin Expression

Aaron Cheng Information

University

Harvard University

Position

Massachusetts General Hospital

Citations(all)

282

Citations(since 2020)

272

Cited By

119

hIndex(all)

5

hIndex(since 2020)

5

i10Index(all)

2

i10Index(since 2020)

2

Email

University Profile Page

Harvard University

Aaron Cheng Skills & Research Interests

genetics

hematology

Top articles of Aaron Cheng

Impact of Degree and Duration of Iron Overload on Incidence of Diabetes Mellitus, Cardiac Disease, and Death in Congenital Hemolytic Anemias

Authors

Aaron Cheng,Hanny Al-Samkari

Journal

Blood

Published Date

2023/11/28

Introduction : Iron overload and its complications are recognized to be morbid and fatal in patients with congenital hemolytic anemias. Much of what is assumed regarding the long-term complications of iron overload in these patients is extrapolated from other patient populations, primarily those with hereditary hemochromatosis. In patients with iron overload caused by congenital hemolytic anemias, there has been no study evaluating the dose-response relationship between serum markers of iron overload and long-term health complications. Filling this critical gap was the aim of the present study.Methods :We evaluated outcomes in a 5-hospital observational cohort study of adults with congenital hemolytic anemias diagnosed with iron overload over a 40-year period (1983-2023). Patients were identified via electronic database query, and eligibility was confirmed and data collection performed via manual chart …

A case report of mesenteric and portal vein thrombosis in a patient with Fusobacterium nucleatum bacteremia

Authors

Aaron N Cheng,Jamie O Brett,Jaspreet Sandhu,Lucy Morse,Rebecca Liu,Junsung Rho,Victor Chiappa,Kathy M Tran

Journal

Thrombosis Update

Published Date

2021/12/1

BackgroundFusobacterium bacteria are fastidious commensals in the human oropharyngeal microbiome. As pathogens, Fusobacterium are associated with diverse infectious and inflammatory conditions, including Lemierre's syndrome, colorectal cancer, and inflammatory bowel disease. Portal and mesenteric thromboses associated with Fusobacterium are case-reportable; due to the rarity of these reports, the full spectrum of presentations and outcomes remains unknown.Case presentationA 71-year-old man presented with two weeks of abdominal pain and night sweats. He was found to have extensive portal and mesenteric venous thromboses and pancolitis. Initial workup for hypercoagulable risk factors was negative; after discharge, blood cultures became positive for Fusobacterium nucleatum. The patient was treated with antibiotics and anticoagulation with complete resolution of symptoms, thromboses, and …

Dissecting the Genetic Architecture of Fetal Hemoglobin Expression

Authors

Aaron Cheng

Published Date

2020

Inducing production of fetal hemoglobin (HbF) is a promising therapeutic approach to ameliorate disease severity in beta-thalassemia and sickle cell disease. While studies have characterized individual genetic factors affecting fetal hemoglobin levels and begun to elucidate some underlying mechanisms, a complete understanding of how these elements interact to influence overall fetal hemoglobin expression levels has yet to be achieved. We hypothesize that varying range of fetal hemoglobin expression in the human population is the result of complex genetic architecture involving the interaction between multiple common and rare genetic variants. To interrogate the underlying genetic architecture of this complex and clinically-relevant trait, we have performed large genome-wide association study (GWAS) from two distinct study populations ascertained in different ways: a Thai population and a Swedish …

See List of Professors in Aaron Cheng University(Harvard University)

Aaron Cheng FAQs

What is Aaron Cheng's h-index at Harvard University?

The h-index of Aaron Cheng has been 5 since 2020 and 5 in total.

What are Aaron Cheng's top articles?

The articles with the titles of

Impact of Degree and Duration of Iron Overload on Incidence of Diabetes Mellitus, Cardiac Disease, and Death in Congenital Hemolytic Anemias

A case report of mesenteric and portal vein thrombosis in a patient with Fusobacterium nucleatum bacteremia

Dissecting the Genetic Architecture of Fetal Hemoglobin Expression

are the top articles of Aaron Cheng at Harvard University.

What are Aaron Cheng's research interests?

The research interests of Aaron Cheng are: genetics, hematology

What is Aaron Cheng's total number of citations?

Aaron Cheng has 282 citations in total.

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