AAM Shimojo

AAM Shimojo

Universidade Estadual de Campinas

H-index: 13

Latin America-Brazil

About AAM Shimojo

AAM Shimojo, With an exceptional h-index of 13 and a recent h-index of 11 (since 2020), a distinguished researcher at Universidade Estadual de Campinas, specializes in the field of Biotecnologia, Engenharia de Tecidos, Medicina Regenerativa.

His recent articles reflect a diverse array of research interests and contributions to the field:

The biomaterial niche of platelet-rich plasma and hyaluronic acid matrices for tissue regeneration

In Vitro Methodologies for Toxicological Assessment of Drug Delivery Nanocarriers

Cellular and molecular toxicology of nanoparticles

New nanotechnologies for the treatment and repair of skin burns infections

Bioactive hybrid nanowires: a new in trend for site-specific drug delivery and targeting

Scaffolds for tissue engineering: A state-of-the-art review concerning types, properties, materials, processing, and characterization

AAM Shimojo Information

University

Universidade Estadual de Campinas

Position

Faculdade de Engenharia Química

Citations(all)

539

Citations(since 2020)

396

Cited By

304

hIndex(all)

13

hIndex(since 2020)

11

i10Index(all)

14

i10Index(since 2020)

12

Email

University Profile Page

Universidade Estadual de Campinas

AAM Shimojo Skills & Research Interests

Biotecnologia

Engenharia de Tecidos

Medicina Regenerativa

Top articles of AAM Shimojo

The biomaterial niche of platelet-rich plasma and hyaluronic acid matrices for tissue regeneration

Authors

Bruna Alice G de Melo,Andrea AM Shimojo,Carla G França,Ângela Cristina M Luzo,José Fabio SD Lana,Maria Helena A Santana

Published Date

2023/1/1

The conjugation of autologous platelet-rich plasma (PRP) and exogenous hyaluronic acid (HA), PRP+HA, has been emerged as a promising regenerative therapy, mainly for musculoskeletal diseases. However, despite the synergistic biological mechanism, its properties depend on PRP and HA quality and conjugate structure. Most studies neglect these relationships, and preparation of PRP+HA is still challenging, being sometimes controversial and lacking standardization. Here, we initially present and discuss the state of the art of PRP+HA in orthopedic applications from the historical background of clinical and in vitro studies. Regarding conjugate structures, we focus on PRP+HA matrices containing HA in microparticles or in a semi-interpenetrating network, with technologies, processing, and in vitro performance. Finally, from the concepts of stem cell and injury niches, we discuss the abilities of PRP+HA …

In Vitro Methodologies for Toxicological Assessment of Drug Delivery Nanocarriers

Authors

Maria C Teixeira,Carolina G Rodrigues,Aleksandra Zielińska,Joana R Campos,Ana R Fernandes,Andrea AM Shimojo,Eliana B Souto

Journal

Nanotoxicology and Nanoecotoxicology Vol. 1

Published Date

2021

Drug delivery nanocarriers (DDNCs) are very suitable systems in drug transport to site-specific targets. The physicochemical characteristics that make DDNCs promising systems for disease therapy can be also correlated with potential adverse effects. In the development of functional DDNCs, both efficacy and safety assessment are crucial. Until now, there is no established testing strategy to perform nanomaterial toxicological evaluation. Several in vitro cell culture models and testing protocols are commonly applied for the safety profile assessment of a nanocarrier; however, a large amount of disperse and conflicting data are generally provided in scientific literature. Thus, systematic research on the toxicological effects of nano-based systems is crucial due to their increasing development, production, and usage. This chapter highlights the critical aspects regarding nanotoxicity assessment, addressing the …

Cellular and molecular toxicology of nanoparticles

Authors

Quaiser Saquib,Mohammad Faisal,Abdulaziz A Al-Khedhairy,Abdulrahman A Alatar

Published Date

2018/2/16

We are pleased to introduce the book entitled Cellular and Molecular Toxicology of Nanoparticles in the Advances in Experimental Medicine and Biology series. This body of work is the melding of a number of ideas and perspectives. Hence, we must thank all the contributors who wholeheartedly welcomed our invitation and agreed to contribute chapters to embellish toxicological information on nanoparticles (NPs). We express our special thanks to King Saud University for all the support. NPs research within the last decade has received tremendous attention due to their unique properties in optics, physical, chemical, and biological processes. Larger NPs surface area and more surface atoms endow them with high chemical reactivity and intrinsic toxicity. As a result, NPs have been adopted in medical biology as an antibacterial agent, DNA structure probes, biosensors in drug and delivery formulations, tissue …

New nanotechnologies for the treatment and repair of skin burns infections

Authors

Eliana B Souto,André F Ribeiro,Maria I Ferreira,Maria C Teixeira,Andrea AM Shimojo,José L Soriano,Beatriz C Naveros,Alessandra Durazzo,Massimo Lucarini,Selma B Souto,Antonello Santini

Published Date

2020/1/8

Burn wounds are highly debilitating injuries, with significant morbidity and mortality rates worldwide. In association with the damage of the skin integrity, the risk of infection is increased, posing an obstacle to healing and potentially leading to sepsis. Another limitation against healing is associated with antibiotic resistance mainly due to the use of systemic antibiotics for the treatment of localized infections. Nanotechnology has been successful in finding strategies to incorporate antibiotics in nanoparticles for the treatment of local wounds, thereby avoiding the systemic exposure to the drug. This review focuses on the most recent advances on the use of nanoparticles in wound dressing formulations and in tissue engineering for the treatment of burn wound infections.

Bioactive hybrid nanowires: a new in trend for site-specific drug delivery and targeting

Authors

AR Fernandes,J Dias-Ferreira,MC Teixeira,AAM Shimojo,Patrícia Severino,AM Silva,Ranjita Shegokar,Eliana B Souto

Published Date

2020/1/1

The current progress of modern medicine is based on the resistance of malignant tumors in advanced medical treatments, as well as on the need to develop new therapeutic approaches. In the last few years, numerous studies have focused their attention on the promising use of nanomaterials, such as nanowires, zinc oxide, or mesoporous silica nanoparticles, among others. All these particles are studied in the treatment of cancer and metastasis prevention with the advantage of operating directly at the biomolecular scale. These are innovative designs of magnetic nanomaterials based on a core/shell approach that started to gain prominence due to their versatility to tailor properties of both core and shell and to offer multifunctionality, such as core protection, biofunctionalization platform, toxicity reduction, and enhanced biocompatibility. These nanowire structural improvements allow the development of new …

Scaffolds for tissue engineering: A state-of-the-art review concerning types, properties, materials, processing, and characterization

Authors

Andréa Arruda Martins Shimojo,Isabella Caroline Pereira Rodrigues,Amanda Gomes Marcelino Perez,Eliana Maria Barbosa Souto,Laís Pellizzer Gabriel,Thomas Webster

Published Date

2020

Given the constant lack of donors for organ transplantation, tissue engineering has been considered a very important tool for regenerative medicine to overcome the limitations of conventional treatments. Tissue engineering is mainly based on obtaining biodegradable three-dimensional (3D) scaffolds. Based on a bibliometric study covering the last three decades of scientific research in scaffolds, this review will address the existing types of scaffolds (solid and fluid); the necessary scaffold properties for adequate tissue regeneration, such as biocompatibility and adequate mechanical properties; the materials that can be used to manufacture the scaffold, from metals to natural and synthetic polymers; scaffold fabrication techniques, considering their advantages and disadvantages and which are the main selection criteria; and finally, the methods of scaffold characterization, such as chemical, morphological …

See List of Professors in AAM Shimojo University(Universidade Estadual de Campinas)

AAM Shimojo FAQs

What is AAM Shimojo's h-index at Universidade Estadual de Campinas?

The h-index of AAM Shimojo has been 11 since 2020 and 13 in total.

What are AAM Shimojo's top articles?

The articles with the titles of

The biomaterial niche of platelet-rich plasma and hyaluronic acid matrices for tissue regeneration

In Vitro Methodologies for Toxicological Assessment of Drug Delivery Nanocarriers

Cellular and molecular toxicology of nanoparticles

New nanotechnologies for the treatment and repair of skin burns infections

Bioactive hybrid nanowires: a new in trend for site-specific drug delivery and targeting

Scaffolds for tissue engineering: A state-of-the-art review concerning types, properties, materials, processing, and characterization

are the top articles of AAM Shimojo at Universidade Estadual de Campinas.

What are AAM Shimojo's research interests?

The research interests of AAM Shimojo are: Biotecnologia, Engenharia de Tecidos, Medicina Regenerativa

What is AAM Shimojo's total number of citations?

AAM Shimojo has 539 citations in total.

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