A. ABU SHQAIR

A. ABU SHQAIR

Seoul National University

H-index: 2

Asia-South Korea

Professor Information

University

Seoul National University

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Citations(all)

7

Citations(since 2016)

7

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0

hIndex(all)

2

hIndex(since 2016)

2

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0

i10Index(since 2016)

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Research & Interests List

Radiation

Top articles of A. ABU SHQAIR

Computational modelling of γ-H2AX foci formation in human cells induced by alpha particle exposure

In cellular experiments, radiation-induced DNA damage can be quantified by counting the number of γ-H2AX foci in cell nucleus by using an immunofluorescence microscope. Quantification of DNA damage carries uncertainty, not only due to lack of full understanding the biological processes but also limitations in measurement techniques. The causes of limited certainty include the possibility of expressing foci in varying sizes responding individual DSBs and the overlapping of foci on the two-dimensional (2D) immunofluorescence microscopy image of γ-H2AX foci, especially when produced due to high-LET radiation exposure. There have been discussions on those limitations, but no successful studies to overcome them. In this paper, a practical modelling has been developed to simulate the occurrences of double-strand breaks (DSBs) and the formations of γ-H2AX foci in response to individual DSB formations, in …

Authors

Ali Abu Shqair,Ui-Seob Lee,Eun-Hee Kim

Journal

Scientific Reports

Publish By

Nature Publishing Group UK

Publish Date

2022/8/23

Development of a User Application for Stochastic Analysis of Dose to Cell Nucleus from Alpha Particle Exposure

High-linear-energy-transfer (LET) radiation, such as alpha particles, delivers energy in a discrete manner among micron-sized target volumes. Hence, mean dose estimate for the cells in vitro cannot inform the real situation of cellular exposures.Geant4 is an open-source Monte Carlo toolkit that offers several physics models of radiation interactions with matter 1. In this study, a user-application has been developed to simulate the exposure of cells in vitro to alpha particles using the Geant4 simulation modules. The application enables doses to individual cell nuclei to be characterized by the average nucleus dose accompanied by the probability density function of the dose.

Authors

Ali Abu Shqair,Eun-Hee Kim

Publish Date

2021/10/21

Multi-scaled monte carlo calculation for radon-induced cellular damage in the bronchial airway epithelium

Radon is a leading cause of lung cancer in indoor public and mining workers. Inhaled radon progeny releases alpha particles, which can damage cells in the airway epithelium. The extent and complexity of cellular damage vary depending on the alpha particle’s kinetic energy and cell characteristics. We developed a framework to quantitate the cellular damage on the nanometer and micrometer scales at different intensities of exposure to radon progenies Po-218 and Po-214. Energy depositions along the tracks of alpha particles that were slowing down were simulated on a nanometer scale using the Monte Carlo code Geant4-DNA. The nano-scaled track histories in a 5 μm radius and 1 μm-thick cylindrical volume were integrated into the tracking scheme of alpha trajectories in a micron-scale bronchial epithelium segment in the user-written SNU-CDS program. Damage distribution in cellular DNA was estimated …

Authors

Ali Abu Shqair,Eun-Hee Kim

Journal

Scientific Reports

Publish By

Nature Publishing Group UK

Publish Date

2021/5/13

Investigating the stress issue of plant personnel under the extreme condition based on the lessons learned from the Fukushima accident

It has been reported that, in NPPs, the human performance average contribution to risk during events is 62%[1]. Therefore, during NPP severe accidents, the humans’ actions role is critical for the wellbeing of human and the environment. In addition, human role provides resilience toward safe conditions when automatic systems fail [2]. On the whole, to achieve this resilience, human performance must be optimized. However, high stress level is a challenge during emergency operation and accidents [3],[4]; which has been proven to contribute to degradation in human performance.Recently, Fukushima accident has uncovered the insufficiency of human performance under extreme conditions [5], and stress was a significant factor during extreme conditions. A previous study found that, during Fukushima, 41.7% of workers experienced near death conditions, 26% witnessed plant explosion, 29% major property loss, and 66.8% evacuated their homes, 5.8% and 17.3% of workers have a family members or colleague, respectively, who had died during the earthquake or the tsunami. All of which increased the workers’ stress during the accident management. Stress issues seem to have attention in the nuclear industry only during the design stage of the control room. However, apparently in Fukushima, many stressors were experienced, led to much high levels of workers’ stress, and no measures were taken to accommodate for that stress during the accident; heightened stress levels and lack of accommodation for them definitely contributed to severity of the accident propagation.

Authors

Ali Abushqair,Young Sik Yoon

Publish Date

2017/10/1

Development of Level 1 Probabilistic Safety Assessment for Jordan Research and Training Reactor (JRTR) in the Framework of IAEA-led Competence Building Project

Jordan Research and Training Reactor (JRTR) is the first nuclear research reactor in Jordan, it has reached its first criticality on 25-April-2016 and is expected to reach full power operation in the upcoming few months. In addition to its scientific value and utilization applications such as radioisotope production and neutron activation analysis, Jordan wanted to have JRTR as the first step toward the establishment of a nuclear power program, where it will open the way to build the experience and knowledge in different fields related to nuclear energy, eg nuclear industry, regulations, international cooperation, etc. The safety of nuclear installations is one of the most important subjects that Jordan needs to build competence in, starting from this point an extra budgetary competence building project COMPASS-J was initiated by IAEA to develop the technical capabilities in Jordan for safety analysis of nuclear installations using the Probabilistic Safety Assessment (PSA) method.The name “COMPASS-J” is a short for “Competence for Probabilistic Assessment of Safety in Jordan”; it was conducted on the basis of learning by doing technique by developing a realistic PSA model for JRTR. The objective of the project is to build an advanced competence of several stakeholders including the utility and Jordan Atomic Energy Commission (JAEC) staff to promote the appropriate use of PSA methods and its results in decision making and accident management that are applicable for the future NPP project, and to have a PSA model and report for JRTR after the beginning of its operation, which can be used for different utility and regulatory purposes, such as the …

Authors

Khalifeh ABUSALEEM Alaaddin ALNAJJAR,Ali ABUSHQAIR,Firas AHMED,Alaa ALDAHYYAT

Publish Date

2016/10

Preliminary Insights regarding Human Reliability Analysis of New Research Reactors from the PSA Study Performed in the Framework of IAEA-led Competence Building Project

One of the outcomes of the extra budgetary project led by the International Atomic Energy Agency (IAEA) and aimed at building competence for Probabilistic Safety Assessment (PSA) in Jordan is a detailed Human Reliability Analysis (HRA) for the Jordan Research and Training Reactor (JRTR). The competence building project named ‘COMPASS-J’is a ‘learning-bydoing project’, which resulted not only in building advanced competence of the Jordanian team of specialists for PSA, but also in a real independent PSA study that provided interesting results and insights. This paper discusses the importance of outcomes and experience acquired on the human factor engineering from the COMPASS-J project to the Jordanian participants. The three types of human actions were considered; Types A and B in the operation mode, and concentrating on Type C human actions to study the possible human actions after the following initiating events: Loss of electrical power, Reactivity insertion accident, Loss of flow accident, Loss of coolant accident, Fuel channel blockage, and General transient.

Authors

Ali ABU SHQAIR,Ala'aldin ALNAJJAR,Firas AHMAD,Khalifeh ABU SALEEM

Publish Date

2016/10

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