Yu-Chen Yen

Yu-Chen Yen

Purdue University

H-index: 9

North America-United States

About Yu-Chen Yen

Yu-Chen Yen, With an exceptional h-index of 9 and a recent h-index of 8 (since 2020), a distinguished researcher at Purdue University, specializes in the field of Structural biology, Structure-based drug design.

His recent articles reflect a diverse array of research interests and contributions to the field:

A Ciliary SMOOTHENED-GRK2-PKA Signaling Pathway Initiates Hedgehog Signal Transduction

Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma

Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ

Isoform Specific Regulation of Adenylyl Cyclase 5 by Gβγ

Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias

Seven structures of atypical chemokine receptor 3 reveal the molecular bases for its promiscuity and signaling bias

Exploring the structural determinants for inhibitor selectivity towards the BACE protein family using structure-based molecular design

Cryo‐EM Structure of Atypical Chemokine Receptor 3 (ACKR3) in Complex with its Endogenous Ligand CXCL12

Yu-Chen Yen Information

University

Position

___

Citations(all)

210

Citations(since 2020)

139

Cited By

112

hIndex(all)

9

hIndex(since 2020)

8

i10Index(all)

9

i10Index(since 2020)

8

Email

University Profile Page

Google Scholar

Yu-Chen Yen Skills & Research Interests

Structural biology

Structure-based drug design

Top articles of Yu-Chen Yen

A Ciliary SMOOTHENED-GRK2-PKA Signaling Pathway Initiates Hedgehog Signal Transduction

bioRxiv

2023

Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma

2023/6/1

Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ

bioRxiv

2023

Isoform Specific Regulation of Adenylyl Cyclase 5 by Gβγ

bioRxiv

2023

Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias

Science Advances

2022/7/13

Yu-Chen Yen
Yu-Chen Yen

H-Index: 5

Martin Gustavsson
Martin Gustavsson

H-Index: 11

Seven structures of atypical chemokine receptor 3 reveal the molecular bases for its promiscuity and signaling bias

The FASEB Journal

2022/5

Exploring the structural determinants for inhibitor selectivity towards the BACE protein family using structure-based molecular design

Biophysical Journal

2022/2/11

Yu-Chen Yen
Yu-Chen Yen

H-Index: 5

Margherita Brindisi
Margherita Brindisi

H-Index: 25

Cryo‐EM Structure of Atypical Chemokine Receptor 3 (ACKR3) in Complex with its Endogenous Ligand CXCL12

The FASEB Journal

2021/5

The Open Question of How GPCRs Interact with GPCR Kinases (GRKs)

Biomolecules

2021/3

Yu-Chen Yen
Yu-Chen Yen

H-Index: 5

A structure-based discovery platform for BACE2 and the development of selective BACE inhibitors

ACS chemical neuroscience

2021/2/5

Yu-Chen Yen
Yu-Chen Yen

H-Index: 5

A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor

Molecular Pharmacology

2020/6/1

Yu-Chen Yen
Yu-Chen Yen

H-Index: 5

See List of Professors in Yu-Chen Yen University(Purdue University)