Tomohiko Hayashi

About Tomohiko Hayashi

Tomohiko Hayashi, With an exceptional h-index of 14 and a recent h-index of 11 (since 2020), a distinguished researcher at Kyoto University, specializes in the field of Biophysics, Computational chemistry, Statistical mechanics of solutions, Life phenomena, Water.

His recent articles reflect a diverse array of research interests and contributions to the field:

Physical pictures of rotation mechanisms of F1-and V1-ATPases: Leading roles of translational, configurational entropy of water

A methodology for creating mutants of G‐protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering

A methodology for creating thermostabilized mutants of G‐protein coupled receptors by combining statistical thermodynamics and evolutionary molecular engineering

Development of an Outward Proton Pumping Rhodopsin with a New Record in Thermostability by Means of Amino Acid Mutations

Controlling the Rigidity of Kinesin-Propelled Microtubules in an In Vitro Gliding Assay Using the Deep-Sea Osmolyte Trimethylamine N-Oxide

Development and structural determination of an anti-PrP C aptamer that blocks pathological conformational conversion of prion protein

Methodology for Further Thermostabilization of an Intrinsically Thermostable Membrane Protein Using Amino Acid Mutations with Its Original Function Being Retained

Hydration properties of a protein at low and high pressures: Physics of pressure denaturation

Tomohiko Hayashi Information

University

Position

Institute of Advanced Energy

Citations(all)

526

Citations(since 2020)

352

Cited By

347

hIndex(all)

14

hIndex(since 2020)

11

i10Index(all)

22

i10Index(since 2020)

15

Email

University Profile Page

Google Scholar

Tomohiko Hayashi Skills & Research Interests

Biophysics

Computational chemistry

Statistical mechanics of solutions

Life phenomena

Water

Top articles of Tomohiko Hayashi

Physical pictures of rotation mechanisms of F1-and V1-ATPases: Leading roles of translational, configurational entropy of water

Frontiers in Molecular Biosciences

2023/6/9

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

A methodology for creating mutants of G‐protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering

Protein Science

2022/10

Simon Hikiri
Simon Hikiri

H-Index: 5

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

A methodology for creating thermostabilized mutants of G‐protein coupled receptors by combining statistical thermodynamics and evolutionary molecular engineering

Protein Science

2022/9

Development of an Outward Proton Pumping Rhodopsin with a New Record in Thermostability by Means of Amino Acid Mutations

The Journal of Physical Chemistry B

2022/1/28

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

Yuki Sudo
Yuki Sudo

H-Index: 18

Controlling the Rigidity of Kinesin-Propelled Microtubules in an In Vitro Gliding Assay Using the Deep-Sea Osmolyte Trimethylamine N-Oxide

ACS omega

2022/1/24

Development and structural determination of an anti-PrP C aptamer that blocks pathological conformational conversion of prion protein

Scientific Reports

2020/3/18

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

Takashi Nagata
Takashi Nagata

H-Index: 16

Methodology for Further Thermostabilization of an Intrinsically Thermostable Membrane Protein Using Amino Acid Mutations with Its Original Function Being Retained

Journal of Chemical Information and Modeling

2020/3/10

Hydration properties of a protein at low and high pressures: Physics of pressure denaturation

The Journal of Chemical Physics

2020/2/14

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

Simon Hikiri
Simon Hikiri

H-Index: 5

Structural and Physical Basis for the Higher Affinity to Oncoprotein MDM2 of a Peptide Selected with MRNA Display Over Tumor Suppressor p53

Biophysical Journal

2020/2/7

How Does a Microbial Rhodopsin RxR Realize Its Exceptionally High Thermostability with the Proton-Pumping Function Being Retained?

The Journal of Physical Chemistry B

2020/1/20

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

Yuki Sudo
Yuki Sudo

H-Index: 18

Comparison based on statistical thermodynamics between globule-to-coil transition of poly (N-isopropylacrylamide) and cold denaturation of a protein

Journal of Molecular Liquids

2020/11/1

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

Simon Hikiri
Simon Hikiri

H-Index: 5

Theoretical identification of thermostabilizing amino acid mutations for G-protein-coupled receptors

2020/4

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

Accurate and rapid calculation of hydration free energy and its physical implication for biomolecular functions

2020/4

Tomohiko Hayashi
Tomohiko Hayashi

H-Index: 10

See List of Professors in Tomohiko Hayashi University(Kyoto University)

Co-Authors

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