Shilin Xu

Shilin Xu

University of Michigan

H-index: 11

North America-United States

About Shilin Xu

Shilin Xu, With an exceptional h-index of 11 and a recent h-index of 11 (since 2020), a distinguished researcher at University of Michigan, specializes in the field of Medicinal chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Discovery of Pyrido[2,3-d]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors …

Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor

Discovery of a PROTAC degrader for METTL3-METTL14 complex

Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy

Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis

Discovery of 7H-Pyrrolo [2, 3-d] pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors

Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase

Structure-based discovery of a series of NSD2-PWWP1 inhibitors

Shilin Xu Information

University

Position

___

Citations(all)

506

Citations(since 2020)

295

Cited By

320

hIndex(all)

11

hIndex(since 2020)

11

i10Index(all)

13

i10Index(since 2020)

12

Email

University Profile Page

Google Scholar

Shilin Xu Skills & Research Interests

Medicinal chemistry

Top articles of Shilin Xu

Discovery of Pyrido[2,3-d]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors …

Journal of Medicinal Chemistry

2024/2/22

Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor

Bioorganic Chemistry

2024/2/1

Discovery of a PROTAC degrader for METTL3-METTL14 complex

Cell Chemical Biology

2024/1/18

Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy

Signal Transduction and Targeted Therapy

2023/12/15

Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis

Journal of Medicinal Chemistry

2023/8/18

Discovery of 7H-Pyrrolo [2, 3-d] pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors

European Journal of Medicinal Chemistry

2023/6/5

Qi An
Qi An

H-Index: 6

Shilin Xu
Shilin Xu

H-Index: 7

Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase

European Journal of Medicinal Chemistry

2022/9/5

Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation

Translational Oncology

2021/8/1

Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor

European Journal of Medicinal Chemistry

2021/7/5

Discovery of M-1121 as an orally active covalent inhibitor of menin-MLL interaction capable of achieving complete and long-lasting tumor regression

Journal of medicinal chemistry

2021/7/1

Piperidines as covalent menin inhibitors

2021/6/29

Piperidine compounds as covalent menin inhibitors

2021/4/22

Follicular lymphoma–associated BTK mutations are Inactivating resulting in augmented AKT activation

Clinical Cancer Research

2021/4/15

Small molecule menin inhibitors

2021/11/18

Piperidines as menin inhibitors

2021/9/8

Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin–MLL Interaction with Strong In Vivo Antitumor Activity

Journal of medicinal chemistry

2020/4/27

See List of Professors in Shilin Xu University(University of Michigan)